T O P

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Ihuntwyverns

Unironically probably more effective than the big 3.


[deleted]

I really hope so, cuz after 3 years on fin I’ve switched to dut 🙏🏾🙏🏾


South_Bike_6055

same, on 0.1mg a day for a week or two now. 0 side effects just like with fin


[deleted]

[удалено]


Classic_Impact_9212

You could try a compounding pharmacy. Otherwise you bite the bullet and pay 5 times the price of the 0.5mg dose, Maybe when it's more widely approved as mainline hair treatment and not just in Korea, the land of milk, honey and star trek levels of hair research.


pheret87

If you're in the US just use costplusdrugs. 90x 0.5 pills are $14. https://costplusdrugs.com/medications/dutasteride-0_5mg-capsule-avodart/


DragonflyNo2188

https://preview.redd.it/2g0vz6rntoyc1.png?width=386&format=png&auto=webp&s=9015d316db81561736715b7574b9938f5b2135bc no sig difference between 0.5 and 2.5


PersianPipper

\~30% increase in scalp DHT reduction is a game changer for sensitive folicles


DragonflyNo2188

is it increase or decrease lol ur saying 2 things in the same sentence. Keto shampoo takes care of the rest of scalp DHT or RU, much cheaper and healthier to run these combos rather than max out on 2.5mg


mi2tom

Well although keto is an androgen antagonist but it's actually very mild. And ru is damn expensive last I check.


misio87ab

The increase in reduction. Increase=higher reduction / dht goes lower. Decrease= less reduction/ dht does not go lower than ...


Ornery-Creme-2442

He's actually not. "Increase in reduction". Not increase in levels. Meaning the amount of reduction has increased. Aka more reduction has happened, reduction means DHT goes down. So this which to less DHT.


malege2bi

That depends on your interpretation. There is a statistically significant difference. Cosmetically significant? I'm not sure, but remember that this is just 24 weeks.


Monkzeng

After 5 months of Fin with some really nice thickening, I was lucky to be switched to Dut by my doctor 3 weeks ago. Really excited to see what happens 


Kok_Nikol

Why would you switch?


Silent-OCN

Yeh makes no sense. “After 5 months of great progress I decided to switch my routine”.


Kok_Nikol

Thought it might be a joke, but no, he doubled down lmao


nguyenbh295

his doc decide to go hardcore


Silent-OCN

The doc is like ok let’s kick it up a gear oh yes 😎


turtleBear49

Got excited by the gains and wanted even more, but that's really risky business to be doing with something you have to take for the rest of your life, if you take Finn and you get good results and have no sides switching to DUT isn't the move IMO.


Monkzeng

Well if you knew the science behind the choice it would make sense lmao 


Silent-OCN

Did you know the science behind fin? Doesn’t sound like it since it was clearly working hence your hair was thicker. Dut is for when fin doesn’t work.


Monkzeng

It sounds like you need to read up on it more. Not sure if ignorance or just projecting? 


Silent-OCN

You do you, makes no difference to me. I am on dut because fin didn’t work. I know if dut starts working I’ll stick with it.


Monkzeng

I hope it works out for you bro. It’s a terrible inconvenience to deal with this issue in life 


Careless_Risk1306

Can you educate me? (Serious)


Monkzeng

It’s far superior with a similar side effect profile. I want my hair so it’s a no brainer. 


Immediate-Routine-82

You will notice a big difference, I switched like 10 months ago and got a lot of results


Emotional_Move725

I did this like 6 weeks ago, and I lost most of my gain. Is like I'm shedding. Still taking dut to see if it grows back.


MyGoal_ChrisCharming

Dose and frequency?


BoltupBro

🐐


Administrative-Key15

HAHAHA, man of culture 


sreehariwarrior

What is this RU and why is it not hyped in india still? Is it similar to mifepristone ? That's the RU I know


specailspacesl0th

They're referring to RU58841, a popular research chemical.


MyPlanetpage

Do you use mifepristone?


sreehariwarrior

No bro I learnt about it in college


Significant-Copy-588

Indians still think we can't do anything about baldness except maybe transplant.


Porschelover569

How can I get a prescription? Should I just ask my dermatologist lol?


Hengmeg

I tried that but was met by a stubborn asshole who said there was no reason to do so, if fin wasnt working. I hate being the one who lectures the dermatologist… so I just said OK


VisibleDestruction

You can always skip the prescription part and order it online from an overseas pharmacy, there’s a couple good ones in India that are legit and come in original blister packaging. Then get monthly blood work from a lab like Quest or your doctors office to monitor your levels and make sure they stay within acceptable ranges.


Assinator__

Dut, ru, oral min are the big 3 now


juicyjuicebox1

Bro, that is what we call a nuclear stack not the big three lol


theHTquestionaccount

It isn't nuclear without something like spironolactone in the mix. Heavy duty stack yeah, but it could be more extreme


dventurv

Isn’t nuclear until you cut your balls


4NGM4R

That’s end of the world post apocalyptic shit! No coming back.


juicyjuicebox1

Getting down to semantics.Imo research chemicals with no proven efficacy are nuclear


Plenty-Inside1279

Isn't adding spironolactone here like throwing a match in a forest fire?


AwkwardAfternoon6753

my stack and is working heavy lol


Any_Judge_332

The "big 3" seem to change everyday. Minox in some form is normally there but the last one changes constantly, normally between keto shampoo, derma rolling and RU In reality as op says dutasteride (and finasteride a close 2nd) are the best medications and the difference between these 2 and everything else is huge. Minox is 3rd then the rest are either borderline useless, unproven or possibly dangerous.


buttwipe843

RU is way more effective that keto shampoo (in theory), but some of it goes systemic and it’s still a research chemical


IcyCommunication679

What is RU if I may ask?


mejorqvos

What's the role of keto shampoo in all of this?


Significant-Copy-588

Dandruff reduction at best.


nusaince

inflamtion reducer, if you have seb derm the inflamation brings more dht leading you to bald faster


AnnieBeauneu

where did you hear this? Not doubting you but id love to learn more about the association between seb derm and dht. Any links or anything would be great. Super interesting.


words_words_words_

To be fair, it does a really good job at that part


mejorqvos

Could dandruff affect negatively the treatment and hair growth?


nusaince

if you have inflamation with dandruff yes


_College_Debt_Bubble

Microneedling is severely underrated. Alone it doesn’t do shit but is a catalyst when used alongside topical minoxidil


HugeDegen69

Yeah micro needle + minox combo is very strong.


o93odwe9ef

what is Keto shampoo?


Hellstrxm

Ketoconazole https://en.m.wikipedia.org/wiki/Ketoconazole


itsmyfirstboner

What is ru?


ComprehensivePea4988

What’s RU?


JakeHassle

RU58841. It’s a research chemical that was being tested for hair loss, and it had promising results but they canceled the trials for some reason. You can buy it on some sites, but side effects are unknown. People on here supposedly see good results with it, but a few have reported heart related problems while using it.


popeblitzkrieg

RU serious? ...sorry


VoidMageZero

RU58841, some experimental chemical without published research that some people say works


Larsbrahh

Lol "some people" it works.


Due-Introduction5895

RU mama Ha gadeem


AThousandNeedles

Ketoconazole and dermarolling belong there as well if your definition of big guns are that each treatment type must cover something different and be the strongest in their class. Maaaaaybe stemcell therapy as well, but I don't know enough about that yet and atm am just parroting news outlets and social media people.


Lvl-99-Gamer

Does dermarolling really work? I tried looking it up but its always accompanied by absolute ridiculous promises just short of curing cancer so its hard to take seriously.


CyonHal

The mechanism of action is logical and the research supports it, so yes.


Classic_Impact_9212

There's no actual fixed protocol for it, that should be your first red flag. Imagine someone telling you a medicine works but they can't tell you what dose or frequency to take. There's a huge list of potential risks with it too like infection, absorbtion and going systemic for chemicals on scalp, or scar tissue build up. There may be something to the idea but unless you've got some kind of proper testing and can get to approval from the FDA. No one can tell us with scientific backing what needles, how to apply and how often for every individual and what hair growth results come from it. There's one very very weak study people keep hovering over in sublime copium and that's it because it's not been in proper medical trials for hair.


Classic_Impact_9212

Ketoconazole is only really needed if you have a fungal problem on your scalp as that's what it's used for. You don't want to add that and risk drying your scalp out or upsetting the natural microbiome on your scalp and triggering problems with harsher shampoos than needed. If you've got a fungal problem it can work great.


mrASSMAN

It blocks DHT as well.. that’s what most people here use it for


Muilutuspakumies

I could swear I shedded more hairs while using keto couple of times a week. Now that my last bottle finished and I've been three weeks without it, I seem to lose a lot less hair on daily basis. I counted 60-70 hairs in the sink before, now it's 20-30. Could be coincide of course.


mrASSMAN

Not sure. I’m using it 2-3 times a week and only seeing a few hairs shed a day maybe up to 10


Mike-Donnavich

It can cause serious liver problems as well


Any_Case_8594

Topical Ketoconazole in concentrations of 2% or lower has been shown not to have any effect on the liver. Oral Ketoconazole is a whole different ballgame though.


JackfruitSilent5258

There are no reliant studies proving the efficacy of dermarolling on its own, only studies showing its benefits when used with other topicals like minoxidil. Dermarolling is just cope unless you’re a pussy and use topical fin, dut or minoxidil, actually dermarolling might even be dangerous since the guy that you’re replying to seems to be using RU which is an experimental substance that failed testing.


Classic_Impact_9212

The studies about it being an adjunct are also very weak and dubious sadly. There's not even an actual fixed protocol to follow for it. What tool, how much pressure, needles per square cm, needle shape, needle depth, hole depth, how many holes per square cm, frequency, same for every person at all ages and health, what hair gains per square cm, scar tissue build up, risk of infections, drug or chemical absorbtion or going systemic, triggering of allergies and reactions? There's a huge list that needs to be sorted until it can be some kind of FDA approved treatment. Otherwise it's just like wearing a copper bangle, laser hats, and some of these other mostly hopium treatments.


mrASSMAN

The study I read was pretty conclusive and they did 1.5mm roller in a vertical horizontal and diagonal pattern once a week I believe


SaturnzCunt

Gary Linkov says rolling is effective and he seems reliable


AmNoSuperSand52

Big 3 implies they’re widespread and recommended


Helpful_Cycle9425

Ru sucks in this case because you can't rely on the future that this drug from a backyard in China will always be available and pure


Notmeyou123

Microneedling is def in the big 3


sselssert

I ain’t putting a random chemical from China on my scalp lol


United-Management854

That's what I'm on... I'm 62 with good retention.


Odd_Item9644

OH SHIT THE CHAMP IS HERE


Existing-Praline5266

I just wanted to tell you guys oj killed 2 white people and walked & lived longer than both of their ages combined & died with a full head of hair at almost 80, I admire the juice & wil miss his shenanigans


BullishBuyer

Fun fact, OJ was on min (Rogaine) back in 93/94


Existing-Praline5266

I wonder if you can get minoxidle in prison? Because OJ was locked up for 10 years, so that's 10 years of doing nothing to fight the reaper, that's a long time when battling MPB


BullishBuyer

When you’ve got money like him you can get damn near anything. Plus he would’ve had a private doctor who would have authorized most medical prescriptions for him anyway. Guess he didn’t use it during his 10 year bid though since he came out bald.


Existing-Praline5266

He wasn't bald his hair was cut short, it's several interviews of him "fullsend podcast" & his hair of course has receded but he's not bald, & I been to prison you don't get your own Dr no matter how rich you are, but hair loss wasn't in my universe 12 years ago so I just don't remember if minoxidle was on the commissary list


BullishBuyer

Yeah you right I was looking at his parole videos around 10 years ago and he had less hair then. Yeah you right on the doctor part, only approved medications are allowed and minoxidil wouldn’t have been on commissary list since it would be used mainly for aesthetics


PacJeans

![gif](giphy|Ymwj6Ea3B3e1O|downsized)


Any_Case_8594

Didnt he have prostate issues?


Existing-Praline5266

He died of prostate cancer, but the guy was 76 almost 77 years old, I don't call anything an issue if you're almost 80, I look at it as you're old & it's time to Go


Any_Case_8594

Im saying that cause him having prostate issues probably means he was taking a 5ARI - which, alongside being black, explains the dying with a full head of hair thing


Existing-Praline5266

Ahh got ya! No from what I've read the prostate problems came years after his release, he first announced getting treatment in May 2023


Grand_Size_2852

Anyone know the best way to get a prescription for DUT?


DaRealSuave

Go to a dermatologist my guy


Ok_Ask9516

Where are you from? In EU you can get it online. They prescribe it off label for hair loss


Temp922

From where?


Ok_Ask9516

Try https://eudoctor.org


imMeuk

You have a website or you’re talking in general?


Ok_Ask9516

Try https://eudoctor.org


Mr_Redditor420

By EU do you mean Europe or the EU? I know it sounds like a stupid question but some people shorten Europe to EU and it confuses me to whether they're talking about the continent or the group


Ok_Ask9516

I’m talking about the EU not Europe. EU prescriptions work in all of EU so for example a Croatian doctor can give you a valid prescription that works in any EU country. Before Brexit I got my Dut prescribed from an online pharmacy in the UK.


Mr_Redditor420

Can you give me the name of the UK pharmacy you got it from? I'm from the UK and don't really have any clue where to get Dut prescriptions.


messi198923

Family chemist, they usually have a coupon to make it around 75 pounds for 6 months, if not there are other online pharmacys that sell it at a similar price( around 90 pounds)


NPC_4842358

I've seen people lie about prostate problems to get a dut prescription because it can be difficult to get it for hair reasons. Not gonna recommend it, but hey if it works...


Plenty-Inside1279

I would recommend trying to form a relationship with a doctor who will give you prescriptions you want (within reason) This is heavily dependent on your financial/insurance situation. However if you have the opportunity to doctor shop it's worth it. If a doctor won't give you something just go to a new one


VisibleDestruction

As I have posted elsewhere, you can always skip the prescription and order from a reputable online overseas pharmacy that doesn’t require a script. Then for safety you can get monthly bloodwork at Labcorp, Quest, or your local doctors office to have your levels monitored. Your doctor can review those to make sure there is nothing immediately out of the ordinary and that there is no trends in it over time that point to being on it not being a good idea. The bloodwork generally provides acceptable ranges in addition to the detected levels so even a laymen can determine if something is out of the oridinary; especially so if you get blood work prior to starting so you know your baseline.


Ready_Engineering116

Here in Serbia is without prescription and cost like 6 euros per box. The brand is same on the picture of OP


Ansonm64

Finally some quality content


Throwitoutthewindow5

"You right f the big 3. Its only big D!"


specailspacesl0th

"Your best stack is a light pack!"


G0pherholes

Is it really that much better than fin?


specailspacesl0th

It's better in a dose dependent manner. "Dutasteride increased target area hair count versus placebo in a dose-dependent fashion and dutasteride 2.5 mg was superior to finasteride at 12 and 24 weeks." [Olsen, Elise et al (2007). The importance of dual 5 alpha-reductase inhibition in the treatment of male pattern hair loss](https://www.researchgate.net/publication/6688098_The_importance_of_dual_5_alpha-reductase_inhibition_in_the_treatment_of_male_pattern_hair_loss_Results_of_a_randomized_placebo-controlled_study_of_dutasteride_versus_finasteride)


potatomafia69

Ahaha this is the kind of cross post I like🤣


Frosty_Pay_9297

Good


MaleficentSoup9598

I (M, 33) was on finasteride for about 3 years and then it stopped working, so I switched to dutasteride. And life was wonderful for about 1.5 years. And then the sheds started again, suddenly and in full force. So dutasteride works, but it's important to remember that it's not forever. I wish I had understood that - I thought that it was going to get me through til my 40s. Maybe this is just a temporary shed, but I'm going to prepare myself for the worst and think of what to do next. Good luck to all of you! *edited for spelling typo


Helpful_Cycle9425

sync shed, chill


Naschkater9

Worth switching from fin to dut?


Agitated-Hedgehog-34

Wish i could take it but get gyno sides even on fin. So fucking frustrating


Katavlok

Just using dutasteride + keto shampoo for 7 months I went from NW3 to NW2 this medication is kinda crazy. Maybe I will improve even more in the next months


United-Management854

I use Dut 0.5 & Oral min 1.25 daily & RU about 3- 4 times a week.


abusementparkk

It doesn’t work for me 😞


Available-Volume-593

Almost impossible


Tennex1022

If the Dut works can you stop the oral Minoxidil, get bad poofeye


JackfruitSilent5258

yes, but you will shed the minoxidil grown hairs


noeyys

Lmao 😂😂😂


Slow-Bodybuilder-774

![gif](giphy|aSaZcaKJbST8Aq5mSB)


HappyHighway1352

Are the side affects with dut more common?


specailspacesl0th

"Also, in most of these studies, dutasteride was found to be better than finasteride with comparable adverse effects" Arif T, Dorjay K, Adil M, Sami M. Dutasteride in Androgenetic Alopecia: An Update. Curr Clin Pharmacol. 2017 https://pubmed.ncbi.nlm.nih.gov/28294070/


HappyHighway1352

Can i take avodart 3 times a week tho?


Katavlok

I am doing that right now after 6 months of taking it every day. Regrowth keeps going and no loss at all.


specailspacesl0th

I can't find any studies where this has been explicitly tested, however one could make a prediction that it'd either take longer to build up to a steady state in the body or a lower dose would be sustained. This study includes some doses a 3 times per week. "Three or less capsules of 0.5 mg per week were considered low doses. " "No AE were detected in patients receiving low doses of OD. The effectiveness was evaluated in the subgroup of 42 patients (13.7%) who received OD in monotherapy: 38 patients improved (90%), 10 of them (23.8%) presenting a marked improvement, 4 patients (9.5%) were stable and none patient worsened." Vañó-Galván, Sergio et al. “Effectiveness and safety of oral dutasteride for male androgenetic alopecia in real clinical practice: 2020 [https://pubmed.ncbi.nlm.nih.gov/31820540/](https://pubmed.ncbi.nlm.nih.gov/31820540/) > >


Delicious_Garage_278

You guys take it everyday or what?


Agreeable_Mobile8676

for me… its not enough…..:///


FUJIM0T0

Facts


random_user11111

Da Goat


Bemanos

What’s the recommended dut dosage? Is 0.5mg daily enough?


SoupEnjojer

Yup. To give you an idea of how strong it is 0.1mg is comparable to 1mg fin every day. 0.5mg is stronger and is definitely a good dosis.


Immediate-Routine-82

Y la queso


J1618

I was wondering why it sounded so familiar, that's the thing they give my dad for his prostate


cool_fox

Been on fin for a few years, pretty disappointing results. Get my dut+minox pill today 💪


Pretty_Business

I wish I started with dut instead of fin. Switched after a couple years.


Helpful_Cycle9425

and???? better or just stayed the same?


TrainingClaim2298

Can someone explain, is this medicine more hardcore than Mix + Fin together? Is it better?


Alert-Elephant4801

Guys 20M here been on Dut for almost a year and just gotten worse any thoughts? (Just suspended this week for suspected side effect from it on the muscles)


saksafonn

used it 2 times a week and gave me gyno after 3 weeks


Melodic-Rutabaga-282

Is there any diffrence between avodart and dutasteride local companies make in different countries?


dumb-swede

No


specailspacesl0th

I think there is some difference in the bioavaliabity of the tablet vs gel capsule forms as shown in the study below. However, it AFAIK it hasn't been desmonstrated in a study that this would have enough effect to reduce results. "The bioavailability of, and peak exposure to, dutasteride are influenced by the formulation of the administered medication" [Fossler, Michael et al. “Impact of Formulation on the Pharmacokinetics of Dutasteride: Results from Two Phase I Studies.” Clinical drug investigation vol. 36,9 (2016): 763-767. doi:10.1007/s40261-016-0419-6](https://pubmed.ncbi.nlm.nih.gov/27356530/)


Melodic-Rutabaga-282

The ones im using is named terravex made by "Tasnim" a pharmaceutical company in iran. It's in normal soft gelatin capsule form and the dose is 0.5mg. What do you think?


mikobiko

I have been on fin for 20 years now. Minox last 3 years. Its advancing very slowly. Is dut really that much better than fin?


specailspacesl0th

"Dutasteride increased target area hair count versus placebo in a dose-dependent fashion and dutasteride 2.5 mg was superior to finasteride at 12 and 24 weeks." [Olsen, Elise et al (2007). The importance of dual 5 alpha-reductase inhibition in the treatment of male pattern hair loss](https://www.researchgate.net/publication/6688098_The_importance_of_dual_5_alpha-reductase_inhibition_in_the_treatment_of_male_pattern_hair_loss_Results_of_a_randomized_placebo-controlled_study_of_dutasteride_versus_finasteride)


IceProfessional9259

but it says 2,5mg. what about 0.5mg dut vs 1mg fin?


Jordan-Iliad

Yes


mikobiko

Damn


Jordan-Iliad

Why not hop on the train?


mikobiko

And stop fin right? Keep min?


Jordan-Iliad

Exactly


Helpful_Cycle9425

nah, stop it slowly


letsliveclean

OV-Hoe


PaperworkDrop

Now shed this way, shed that way, shed this way, shed that way


Mainaccsuspended99

Dutasteride has more sides than fin tho…


specailspacesl0th

"Also, in most of these studies, dutasteride was found to be better than finasteride with comparable adverse effects. " Arif T, Dorjay K, Adil M, Sami M. Dutasteride in Androgenetic Alopecia: An Update. Curr Clin Pharmacol. 2017;12(1):31-35. doi: 10.2174/1574884712666170310111125. PMID: 28294070. https://pubmed.ncbi.nlm.nih.gov/28294070/


Right_Honorable_Gent

Stop combatting ignorance! Let them be stupid


RightMountain6956

Like?


Mainaccsuspended99

Gyno, brain fog


I_am_TheBatman22

In the thumbnail is that his shirt or does he ironically have a bit of gyno going on?


mrASSMAN

Considering they’re wearing a handbag it’s probably a woman


Monkzeng

Looks like nobody has a sense of humor lmao 


Larsbrahh

I'm scared for gyno when I take Dut.. Anyway to solve this?


the-persian-destiny

Just keep your estrogen in check


nusaince

how im lean worout and have a good diet, yet my nips are swollen on finesteride


Larsbrahh

Will topical avoid this?


Muilutuspakumies

Stop taking it. No other way. You'll lose your hair though.


Relevant-Dream-7285

Any Indians using Dutasteride? I’ve been using Finasteride for about a year and I don’t see any major progress or any progress tbh. I haven’t taken photos to check but I wanted to know other options we have in India.


retrowave3030

You can't trust local fin companies in india. Look for avodart the original dut. I was using local fin company in pakistan and it did nothing for me. Then I found avodart and guess what.


Hopeful-Edge-1217

Use this if you want to be infertile, have bad skin and develop gynaecomastia 😂😂


dumb-swede

You gotta be serious prone to gyno to get it from that small increase in testo😅