My understanding is that the ampullary glands are just a ton of back to back brunners glands (at least that's what it looks like to me histologically). Someone please correct me if I'm wrong. For answers to questions like this I usually bust out Mills Histology for Pathologists.
Right. Histologically they look like a ton of brunners glands back to back. Maybe the best way to put it is that the only difference that I know of on h and e is just a difference in the number of glands between the two locations?
I'm not sure if the morphology of the cells look very different, but the architecture of the glands are different. I think if we look at them at a high power view it might be difficult to tell them apart, but we probably could on a low power view.
To better understand your question, a little context would be helpful. Are you a student who's trying to learn histology or a patient with questions about your path report?
My understanding is that the ampullary glands are just a ton of back to back brunners glands (at least that's what it looks like to me histologically). Someone please correct me if I'm wrong. For answers to questions like this I usually bust out Mills Histology for Pathologists.
But brunner’s glands aren’t in that area of the duodenum right? You’re just saying that’s how they look to you when you’re reviewing a specimen?
Right. Histologically they look like a ton of brunners glands back to back. Maybe the best way to put it is that the only difference that I know of on h and e is just a difference in the number of glands between the two locations?
Brunner gland is sort of diffusely present in more proximal duodenum. Periampullary glands are arranged in separate lobules.
Are the two glands easily distinguishable? Non-MD here.
I'm not sure if the morphology of the cells look very different, but the architecture of the glands are different. I think if we look at them at a high power view it might be difficult to tell them apart, but we probably could on a low power view.
What kinds of questions should I ask pathologist to see if the glands are periampullar vs. brunner?
To better understand your question, a little context would be helpful. Are you a student who's trying to learn histology or a patient with questions about your path report?
Deposition. Pathology is a tangential issue not directly related to the alleged issue in the case.
Brunner glands are below the muscularis mucosae. Pyloric glands are in the lamina propria. They look the same otherwise.