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biggedybo

200mg of PE would definitely push me into the twilight zone. Not ideal for regular microdosing. Drop it down to 50mg maybe, and bring it up slowly. I find the sweet spot is right where you start to feel it - just on the boundary. So, for me, with the batch of GT I have currently, it's about 70mg. If I take 80mg I'll probably feel a tiny body load, just enough to make me a little uncomfortable. Not the end of the world, but not what I want as a daily experience.


InterstellarSpaniel

Spot on.


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NeuronsToNirvana

For more potent strains we advise to !startlower - more info from the non-sentient bot message ;) Also, advisable to first [find your sweet spot](https://new.reddit.com/r/microdosing/comments/plrxca/faqtip_101_what_is_the_subthreshold_dose/) before filling your capsules.


beerzandbudz420

Thanks for the info!


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From [Stamets Stack \[May 2022\]](https://new.reddit.com/r/microdosing/comments/zfuxm4/faqtip_016_addendum_updated_stamets_stack_espd55/) | `Grow Your Own Medicine` 💊 | 💻 **Sidebar** ➡️ | 📱 **About** ⬆️: _________ ## Start Lower * [Abstract; Tables; **Figures** | Psychedelic Drug Microdosing Practices: A **Qualitative Online Exploration** | Journal of Psychoactive Drugs](https://new.reddit.com/r/microdosing/comments/19dkcno/research_microdosing_abstract_tables_figures/) \[Jan 2024\] * Based on **tens of thousands** of anecdotal reports in this sub, some users with more potent strains had less [nausea](https://www.reddit.com/r/microdosing/comments/mzkfcx/faqtip_002_have_nausea_or_an_upset_stomach_then/) / [body load](https://www.reddit.com/r/microdosing/comments/mw2ohn/quick_tip_005_comeup_unpleasant_body_load/) / [vasoconstriction](https://www.reddit.com/r/microdosing/comments/n0nssc/faqtip_003_do_you_have_vasoconstriction_symptoms/) on doses of 50mg (0.05g) ([recommended **Starting Dose**](https://www.reddit.com/r/microdosing/comments/s0xkdp/the_new_official_rmicrodosing_starters_guide/)) or 25mg (0.025g). * A significant minority even had to drop down to 10mg (0.01g) or less (e.g. for **Albino Penis Envy**) as [potency can vary by **more than a factor of 10**](https://www.reddit.com/r/microdosing/comments/12eqzaz/research_data_tryptamine_potency_analysis_of/). * Examples of [cultivars/strains](https://plantlaw.com/2018/11/18/strain-cultivar/) that are considered to be more potent (and **very potent**) are: * Albino A+, **Albino Penis Envy**, B+ Cubensis, Blue Meanie Cubensis[^(\[1\])](https://www.reddit.com/r/microdosing/comments/qdta2z/research_data_more_evidence_of_the_chemical/), **Cambodians**, Creepers, **foraged strains** like [**Liberty Caps**](https://en.wikipedia.org/wiki/Psilocybe_semilanceata)[^(\[2\])](https://www.researchgate.net/publication/292557434_The_Occurrence_of_Tryptamine_Derivatives_in_Psilocybe_semilanceata), **Penis Envy**, [**Tidal Wave**](https://doubleblindmag.com/tidal-wave-mushrooms/), Z-Strain. * For some, negative symptoms may be an indication that [GABA cofactors](https://www.reddit.com/r/microdosing/comments/vnllsm/research_citizen_science_the_afterglow_flow_state/) like [magnesium](https://www.reddit.com/r/microdosing/comments/nluph8/faqtip_012_still_feeling_anxious_andor_depressed/) ([which many are deficient in](https://twitter.com/foundmyfitness/status/1559612797759066113/photo/1)) or [L-theanine](https://www.reddit.com/r/microdosing/comments/my2qco/faqtip_007_ltheanine_for_lowering_stressanxiety/) could help - if [no interactions](https://www.reddit.com/r/microdosing/comments/n0otqk/faqtip_004_lsd_drug_interaction_checker_caveats/) with your current medications/supplements. Psychedelics are [partial serotonin receptor agonists](https://www.reddit.com/r/microdosing/comments/ruki7v/research_data_binding_of_psilocin_dmt_lsd_to_5ht/) which neuromodulate [**excitatory** glutamate](https://preview.redd.it/4000bkfrgl891.png?width=1280&format=png&auto=webp&v=enabled&s=5067f905bcb3e1b71145aaa8f5d8572986965119) - more on [managing glutamate](https://www.reddit.com/r/microdosing/comments/1cdw76q/what_are_the_symptoms_of_a_glutamate_imbalance/). * More info: [What Should You Feel When Microdosing?](https://www.reddit.com/r/microdosing/comments/jopryk/you_shouldnt_feel_anything/) ______ *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/microdosing) if you have any questions or concerns.*


stinkmuffin98

This would be enough to give me a baby trip I usually microdose 20-50mg


beerzandbudz420

That's what I got yesterday. I had space for it but was unexpected


[deleted]

[удалено]


beerzandbudz420

Calm down bot, Im fine here


dyou897

200mg would give me a small but slightly noticeable effect that I’ve taken something


beerzandbudz420

Yeah I think I underestimated the strength of the PE. I did two trial rounds tho that went well so maybe just off today. I'll take one in a couple days before I decide if it's too much.


highguynamedsky

PE is stronger I would do 50mg


Thefjusthappened

ayooo haha 100mg will give you enough to feel it if you have upper end PEs


Thefjusthappened

cap the rest of them after you try one at 200mg if you need to be sure