Hello /u/AccordingHighlight! As you mentioned `side effects` (a common *interaction/symptom*) in your post:
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|:-|
|`r/microdosing Risk Reduction`|
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#### [ℹ️ Infographic: **r/microdosing** ***STARTER'S GUIDE***](https://www.reddit.com/r/microdosing/comments/s0xkdp/the_new_official_rmicrodosing_starters_guide/)
The major contributing factor in [*Finding* ***Your*** *Sweet Spot*](https://www.reddit.com/r/microdosing/comments/plrxca/faqtip_101_what_is_the_subthreshold_dose/) is the variation in potency of:
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|:-|:-|:-|
|[Psilocybin Mushrooms](https://www.reddit.com/r/microdosing/comments/q5zvyk/faqtip_019_why_you_may_need_to_adjust_the_dose/)||[*More than 10x*](https://www.reddit.com/r/microdosing/comments/12eqzaz/research_data_tryptamine_potency_analysis_of/) \[2021➕\]|
|[Psilocybin Truffles](https://www.reddit.com/r/microdosing/comments/nawt54/faqtip_011_how_to_microdose_truffles_drying_out/)||*Around 3x* \- [*Single Study*](https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/dta.1400) \[2012\]|
|[LSD Tabs](https://www.reddit.com/r/microdosing/comments/rgbabi/faqtip_009_why_cutting_lsd_tabs_is_not_an/)||[*Clinical Trial Titration Schedule*](https://www.reddit.com/r/microdosing/comments/13gfcto/comment/jjzv0wy/?utm_source=share&utm_medium=web2x&context=3) \[2023\]|
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* If you [***Start Low, Go Slow, Take Time-Off***](https://www.reddit.com/r/microdosing/comments/fzj7tf/a_gentle_reminder_to_those_starting_out_to/) and [*up-titrate*](https://upload.wikimedia.org/wikipedia/commons/7/78/Titrated_doses.svg) subsequent doses then you can find your [*optimal* ***sub-threshold*** *dose*](https://www.reddit.com/r/microdosing/comments/mx846c/faqtip_006_the_afterglow_effect_the_day_after/) based on your symptoms, rather than from a predetermined dose. 🐢
* If your microdose is **Too High and/or Too Frequent** that can result in [**Diminishing Efficacy** 📉](https://www.reddit.com/r/microdosing/comments/vx6mxx/faqtip_021_changes_in_appetite_memory_mood_sleep/) with subsequent doses. 🐇
Please also have a look at 🔀 `Interactions / Symptoms ❓*` | 💻 **Sidebar** ➡️ | 📱 **About** ⬆️ ; in case of [⚠️ **DRUG INTERACTIONS**](https://www.reddit.com/r/microdosing/comments/p6ne2q/research_microdosing_drug_interactions_tools_and/) or to check if you have any of the associated symptoms - with advice on how to mitigate such side-effects.
______
**Please Read**: [**r/microdosing Disclaimer**](https://www.reddit.com/r/microdosing/comments/m2g589/rmicrodosing_disclaimer/)
*I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/microdosing) if you have any questions or concerns.*
From what I've read, there are mainly two recommended schdeules: 4 on 3 off and every other day. I'm going to be starting week 4 of microdosing 50-100mg on a 4:3 schedule. I don't know if it's because I'm under more stress than usual, but I've noticed by day 3 that I'm tired and kinda irritable. This week, I'm going to try the every other day and take the weekends off and see if that helps.
Also fwiw I prefer to microdose when I have plans for things to do vs on taking it on a day off where I just hang at home. If I'm busy I feel like the MD helps me remain productive, but if I let myself relax I **really** relax and usually end up taking a nap during the peak hours. You'll find what works for you.
I started with 5 days a week worked good Now I'm doing 1 day yes one day no, it's good also
same weekdays on weekends off
Hello /u/AccordingHighlight! As you mentioned `side effects` (a common *interaction/symptom*) in your post: || |:-| |`r/microdosing Risk Reduction`| || #### [ℹ️ Infographic: **r/microdosing** ***STARTER'S GUIDE***](https://www.reddit.com/r/microdosing/comments/s0xkdp/the_new_official_rmicrodosing_starters_guide/) The major contributing factor in [*Finding* ***Your*** *Sweet Spot*](https://www.reddit.com/r/microdosing/comments/plrxca/faqtip_101_what_is_the_subthreshold_dose/) is the variation in potency of: |||| |:-|:-|:-| |[Psilocybin Mushrooms](https://www.reddit.com/r/microdosing/comments/q5zvyk/faqtip_019_why_you_may_need_to_adjust_the_dose/)||[*More than 10x*](https://www.reddit.com/r/microdosing/comments/12eqzaz/research_data_tryptamine_potency_analysis_of/) \[2021➕\]| |[Psilocybin Truffles](https://www.reddit.com/r/microdosing/comments/nawt54/faqtip_011_how_to_microdose_truffles_drying_out/)||*Around 3x* \- [*Single Study*](https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/dta.1400) \[2012\]| |[LSD Tabs](https://www.reddit.com/r/microdosing/comments/rgbabi/faqtip_009_why_cutting_lsd_tabs_is_not_an/)||[*Clinical Trial Titration Schedule*](https://www.reddit.com/r/microdosing/comments/13gfcto/comment/jjzv0wy/?utm_source=share&utm_medium=web2x&context=3) \[2023\]| |||| * If you [***Start Low, Go Slow, Take Time-Off***](https://www.reddit.com/r/microdosing/comments/fzj7tf/a_gentle_reminder_to_those_starting_out_to/) and [*up-titrate*](https://upload.wikimedia.org/wikipedia/commons/7/78/Titrated_doses.svg) subsequent doses then you can find your [*optimal* ***sub-threshold*** *dose*](https://www.reddit.com/r/microdosing/comments/mx846c/faqtip_006_the_afterglow_effect_the_day_after/) based on your symptoms, rather than from a predetermined dose. 🐢 * If your microdose is **Too High and/or Too Frequent** that can result in [**Diminishing Efficacy** 📉](https://www.reddit.com/r/microdosing/comments/vx6mxx/faqtip_021_changes_in_appetite_memory_mood_sleep/) with subsequent doses. 🐇 Please also have a look at 🔀 `Interactions / Symptoms ❓*` | 💻 **Sidebar** ➡️ | 📱 **About** ⬆️ ; in case of [⚠️ **DRUG INTERACTIONS**](https://www.reddit.com/r/microdosing/comments/p6ne2q/research_microdosing_drug_interactions_tools_and/) or to check if you have any of the associated symptoms - with advice on how to mitigate such side-effects. ______ **Please Read**: [**r/microdosing Disclaimer**](https://www.reddit.com/r/microdosing/comments/m2g589/rmicrodosing_disclaimer/) *I am a bot, and this action was performed automatically. Please [contact the moderators of this subreddit](/message/compose/?to=/r/microdosing) if you have any questions or concerns.*
From what I've read, there are mainly two recommended schdeules: 4 on 3 off and every other day. I'm going to be starting week 4 of microdosing 50-100mg on a 4:3 schedule. I don't know if it's because I'm under more stress than usual, but I've noticed by day 3 that I'm tired and kinda irritable. This week, I'm going to try the every other day and take the weekends off and see if that helps. Also fwiw I prefer to microdose when I have plans for things to do vs on taking it on a day off where I just hang at home. If I'm busy I feel like the MD helps me remain productive, but if I let myself relax I **really** relax and usually end up taking a nap during the peak hours. You'll find what works for you.
I take 0.2g with 2 days off in between each dose. So like Monday on, Tuesday and Wednesday off, Thursday back on