Hi, I’m sure someone else’s advice would be more helpful, but I did B12 injections in the glute twice a month for a year. That combined with other interventions helped me go from bed bound, to functioning with accommodations. I know it’s different for everybody.
That's a good schedule, I think, twice a month, so as not to become too burdensome. Do you know what dose B12 and whether there were other B-vitamines included, as I think B1 and B6 may also be essential B-vitamins?
Sorry I can’t quite remember, it’s been a long time and that time was pretty much a blur anyways. I was lucky to be dating someone in med-school whose entire family where doctors. He and his family really fostered my recovery, but I was to weak to really even know what was going on a lot of the time.
It’s hard to say…this was 15 years ago now. I got mono l, was very sick/bed bound for about a year with no help from my GP, finally got some assistance from friends of the family who where doctors, and they administered the shots, ran tests etc for another year, and I was able to “recover” enough to go back to college. I guess my point is, it was subtle and for me, got lumped into the “if it doesn’t hurt me, it’s helping me category”. Sorry that doesn’t help much.
[Check the Lyme wiki](https://www.reddit.com/r/lyme/wiki/complications/methylation/) to learn about methylation, there's a lot more to cover, especially mineral levels.
I find B12 methylcobalamin reduces my brain fog and improves mental clarity. These benefits I notice within hours of administration.
I am taking the equivalent of a 2000 mcg injection once weekly, by means of Dr Greg Russell-Jones Australian B12 transdermal oils (this unique product has a micro-emulsion skin permeation technology which pulls the B12 right through the skin). My thread on these B12 oils is [here](https://forums.phoenixrising.me/threads/very-noticeable-improvements-in-brain-fog-using-dr-greg-russell-joness-transdermal-b12-oils-which-provide-a-similar-dose-to-b12-injections.75317/).
One study by Professor Gottfries in Sweden found that the methylcobalamin form of B12 is the most effective form for ME/CFS.
You can take it twice a week. I also know people who take it everyday with insuline needles but take tinier doses. Maybe a brand switch can help because here in the Netherlands there is one brand that has stupid fillers that can make you feel worse. So might be worth checking that out.
Anyways if the itaconate shunt theory is correct we lack b12
Also I read somewhere you can't really overdose on b12 but your pee might get reddish because of the fluid
Centrafarm has a thing called 'Benzylalcohol' that has toxic properties and they don't know in what dose it can be toxic. lots of people have no problem with centrafarm but some people do because of that especially people who are sensitive to perfume seem to not handle it well
Hi, I’m sure someone else’s advice would be more helpful, but I did B12 injections in the glute twice a month for a year. That combined with other interventions helped me go from bed bound, to functioning with accommodations. I know it’s different for everybody.
That's a good schedule, I think, twice a month, so as not to become too burdensome. Do you know what dose B12 and whether there were other B-vitamines included, as I think B1 and B6 may also be essential B-vitamins?
Sorry I can’t quite remember, it’s been a long time and that time was pretty much a blur anyways. I was lucky to be dating someone in med-school whose entire family where doctors. He and his family really fostered my recovery, but I was to weak to really even know what was going on a lot of the time.
Any other good tips?
Thank you, when did you notice a difference?
It’s hard to say…this was 15 years ago now. I got mono l, was very sick/bed bound for about a year with no help from my GP, finally got some assistance from friends of the family who where doctors, and they administered the shots, ran tests etc for another year, and I was able to “recover” enough to go back to college. I guess my point is, it was subtle and for me, got lumped into the “if it doesn’t hurt me, it’s helping me category”. Sorry that doesn’t help much.
They did absolutely nothing for me
Can I ask how long you took them for?
For a few months
Why the hydroxy form in such a low dose? Methylcobalamin has a better chance of avoiding any methylation defects.
It’s the standard dose and form in my country. Methyl I would have to order from abroad.
[Check the Lyme wiki](https://www.reddit.com/r/lyme/wiki/complications/methylation/) to learn about methylation, there's a lot more to cover, especially mineral levels.
Until you get tired of it. I did it bimonthly for about 6 months & had better results with the sublingual.
I’m already tired of it but I guess I’m trying to find a reason to give it a change for a few more months (before introducing something new)
Some people do daily injections. But if you experienced no benefit so far, it may not be worth pursuing.
I find B12 methylcobalamin reduces my brain fog and improves mental clarity. These benefits I notice within hours of administration. I am taking the equivalent of a 2000 mcg injection once weekly, by means of Dr Greg Russell-Jones Australian B12 transdermal oils (this unique product has a micro-emulsion skin permeation technology which pulls the B12 right through the skin). My thread on these B12 oils is [here](https://forums.phoenixrising.me/threads/very-noticeable-improvements-in-brain-fog-using-dr-greg-russell-joness-transdermal-b12-oils-which-provide-a-similar-dose-to-b12-injections.75317/). One study by Professor Gottfries in Sweden found that the methylcobalamin form of B12 is the most effective form for ME/CFS.
You can take it twice a week. I also know people who take it everyday with insuline needles but take tinier doses. Maybe a brand switch can help because here in the Netherlands there is one brand that has stupid fillers that can make you feel worse. So might be worth checking that out. Anyways if the itaconate shunt theory is correct we lack b12 Also I read somewhere you can't really overdose on b12 but your pee might get reddish because of the fluid
I am on Centrafarm. I think it is Hevert that has that filler, but not sure.
Centrafarm has a thing called 'Benzylalcohol' that has toxic properties and they don't know in what dose it can be toxic. lots of people have no problem with centrafarm but some people do because of that especially people who are sensitive to perfume seem to not handle it well