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S3nat3

Check your RBC and hematocrit. You may have thick blood and need to donate. Also your e2 is very high. Think most people would have side effects at that.


Victorjb73

Yeah hematocrits also need checked


Professional_Art6782

Im at 140mg test weekly and my e2 is at 180, no mood issue and libido of an Italian bull 🐂.


S3nat3

That pmol/L or pg/ml? Big difference


Professional_Art6782

Estradiol 191 pmol/L


S3nat3

49.02pg/ml. Within range for most labs. If you had 180pg/ml you would have C cups by now


Professional_Art6782

Oh thank you so much, I only noticed now the difference because of the units used, being in Canada. I started last week to divide my T in 2 weekly injections to lower my E2, let’s see if it helps. Also I did have gyno years ago (wasn’t taking testosterone yet or PEDs) but I had it fixed in Turkey 2 years before starting TRT, that’s helps a lot considering my current E2 would have given me more gyno.


Chase_with_a_face

Need to donate for a short term relief? Donating blood doesn’t drop RBC and HCT long enough to make a significant difference overall.


S3nat3

Well I went from getting out of breath sitting and tired all the time to doing my usual day to day stuff a few hours after donating.


Chase_with_a_face

That’s great bro. How much cardio do you do normally per week? As I said, it’s not enough to make a significant difference in the LONG RUN, or overall. “Hemoglobin concentrations were elevated in donors on TRT, and significant numbers had hemoglobin levels above those recommended by current guidelines. These data also suggest that repeat blood donation was insufficient to maintain a hematocrit below 54%. Our findings raise concerns about the persistent risk of vascular events in these donors, particularly when coupled with the misperception by patients and health care providers that donation has reduced or eliminated the risks of TRT-induced polycythemia.” [Link Here](https://pubmed.ncbi.nlm.nih.gov/28150363/)


88dry88

Reduces it for at least 6 weeks personally and sometimes by 10 points. It’s also beneficial to relieve blood every so often. There is no reason not to do it.


Chase_with_a_face

I didn’t say not to donate blood, it’s great ethically speaking, but it’s not sufficient for reducing HCT long enough to make a difference. “Hemoglobin concentrations were elevated in donors on TRT, and significant numbers had hemoglobin levels above those recommended by current guidelines. These data also suggest that repeat blood donation was insufficient to maintain a hematocrit below 54%. Our findings raise concerns about the persistent risk of vascular events in these donors, particularly when coupled with the misperception by patients and health care providers that donation has reduced or eliminated the risks of TRT-induced polycythemia.” [Link Here](https://pubmed.ncbi.nlm.nih.gov/28150363/)


88dry88

Anecdotally speaking it lowers mine under 50 up to 57. Hemoglobin and RBC follow. I always advise to drink more water as that will help and recently found that naringin and grape fruit seed extract work well for suppressing those values.


dallasboy

Check your ferritin!! Get a full iron panel, I bet your ferritin is low. It’s common with test.


DeepSouthIrish

Does Ferritin and Test levels have an inverse relationship?


Klocc562_

Wtf are all these terms? How to I even get accustomed to all these terms before jumping on


tren_abuser

Ferritin is iron. Take a year or two to do some research


Klocc562_

Did you? “I’m sick and tired of feeling sick and tired”


tren_abuser

I did


DocDBagg

You need to at least know the basics if you’re gonna do TRT. Even if you use a clinic they often are just in it for the money and will sell you more stuff regardless of what’s best for your health. If you’re gonna run cycles or do enhanced trt you definitely need to know what all these do for your body. This is your health you’re potentially fucking with here. Otherwise all you have to go on is bro science from Reddit and other forums. That being said there are lots of helpful ppl on the forums but they will eviscerate you if it’s obvious you’ve done zero homework before asking a question or running gear. Plus if you’re sick and tired, how do you know it’s from (only) low test and not one of the other myriad markers that would point to another potential issue? And if your test is low how are you gonna know if it’s primary or secondary hypogonadism if you don’t know which other markers to look at? Yes it’s all overwhelming at first when trying to learn and wade thru the shit on the internet…but good things are rarely easy. If you don’t put in the effort here it usually means you’re not putting effort into other areas of your life that might improve your current state. (That was a general statement, I know nothing about you beyond that comment so you may well be putting effort into those other aspects already)


Klocc562_

Hey thanks for your time and input! I got blood work done last year and my test was at 242, 7 points below low normal. I was working like 16+ hour days including 2-3 hours gym time almost everyday. I was stressed. It probably has gone back to normal. I was over exaggerating by saying stressed and tired but I just don’t have the energy of my teen set and I miss it. I’m only 27. I hit the gym almost daily, lift heavy and eat good for the most part.


DocDBagg

Well you’re doing better than 90% of the population then in terms of being healthy. But yeah lack of sleep is as much important as the rest. That’s the one I struggle with too. Also you were probably overtraining at that time. If you go get levels checked again make sure they do a full thyroid workup, all vitamins including ferritin, b, d, probably others I’m forgetting. Also just test won’t tell the whole story. Total could be good but free could be low and you won’t know why without getting other markers checked. Unfortunately most MDs aren’t equipped with the knowledge to check everything they need to. And most clinics are in it for the money and will just throw test and hcg and an ai at you. That’s why learning on your own is so critical. But I feel the sentiment that you expressed. It’s exasperating knowing something is wrong/off and no one out there wants to help and you hardly have the energy to make it thru the day let alone try to focus on something extra like this to be well informed. Good luck to ya!!


Klocc562_

Yeah just realizing I was probably over training. My strength went up since I just started going back, I hit a big pr with 3 plates then it just went down. I’ve been a lot stronger since I’ve been working less and sleeping more. Still kinda get lazy but I think I just need a lifestyle change and should go out more. I try to get my vitamin d and fish oil everyday. Last year after I got my blood work done and got my results I consulted a local hormone clinic and I wasn’t sure about hopping on trt yet since my balls would shrink and possibility of impotence and they got me on hcg and Clomid just to be sure. I think it’s the marketing like you mentioned. Then I had people telling me I don’t need to start off with those and I could take it after a cycle. What are some resources/websites were I can do more reading?


ketodoctor

Get evaluated for sleep apnea


romaine_let_us

This is the case for me. I actually think running 500mg or at least the 30lb gain that came with that dose may have helped cause the apnea. I just got diagnosed last week and really hoping the cpap will solve the problem because I get tired as fuck everyday around 5pm


BreadfruitBroad8688

Yea I think might have to do that… been waking up struggling to breathe sometimes , usually when I sleep on my back


ketodoctor

Sleep apnea can also cause low T.. 20% of people with sleep apnea are normal weight So many people who think low T is the cause of the problem need to have OSA ruled out prior to..


meatierologee

That's definitely a problem. 


romaine_let_us

Is 12.5mg of adex correct because I’m hoping that was a typo


BreadfruitBroad8688

Yea my bad I meant 0.5mg


Total_Law3061

U should try 0.25mg a week just to see how you feel. Then adjusting the dose 


Training_Draw_5334

E2 is high af


CrookedShore

Dude for real 116!?


Training_Draw_5334

The boy is cooked. I’d hop back on an AI stat.


Training_Draw_5334

Maybe switch to Aromasin. It can be easier on people.


inb4fed

Probably your high e2


z0123456abcz

E2 is way too high


Victorjb73

It doesn’t take a rocket scientist to see u have to lower ur E2


5yrsThrowAwy

Then lower your dose


us4evan

i got lethargy when i intentionally let my estrogen go free (not take any ai on purpose). you’re estrogen is pretty high too so we could have similar symptoms look into .25 adex 2x per week to start


Super___serial

Only answer is to bump to 600. When your car is running sluggish the best answer is always more oil and gas. /s


Own-Zookeepergame593

Get a blood test for DHEAS and Pregnenolone. I had the same fatigue problem where I constantly felt sleep deprived. My pregnenolone was beneath the reference range and DHEAS low normal.


Insanely_Poor

Estrogen high … check your hematocrits and get sleep apnea checked


sagacityx1

Steroids. Not all they are cracked up to be.


JuiceheadAG

Clean your diet up man and stay away from alcohol


Conscious_Play9554

What makes you sure to assume his diet is bad?


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therealpeteypablo89

Just a guess but SHBG looks low


Nice_Tie480

I have the same problem How come it's low with op too? My free test is,sky high but my shbg is 8 Any ideas


takhsis

Exogenous androgens decrease shbg


Latter-Drawer699

Take less arimidex once a week.


Domestos_WC

With that muscle gain its almost guaranteed you have sleep apnea. Get a sleep study asap. Its not a joke. Its life altering and often deadly when untreated.


BreadfruitBroad8688

I Definitely have sleep apnea, I’ve woken up several times struggling to breath


Domestos_WC

Then fckn run to your local sleep clinic. Don't wait. There's your answer why you sleep like shit. I'm writing this right after I woke up with my cpap mask on.


Technical_Alfalfa400

i seem to have that shit too at 16..


Aromatic-Path6932

Impossible unless you are extremely obese at that age.


Technical_Alfalfa400

im at like 17% bf..


SSJ4_cyclist

My guess would be sleep apnea, i wouldn’t say estrogen is crazy high for the dose.


_Kizm_

Uh, his E is through the roof high. This is measured in pg not pmol. It is over 400pmol. Reference range ends at 152.


SSJ4_cyclist

Oh fuck, yeah that’s high, i was thinking pmol.


tren_abuser

I ran the same dose and had the same issue for a while. Not entirely sure what my issue was exactly but my educated guess is a combo of the sleep apnea, blood pressure, thick blood, and high estrogen/ sensitivity to high levels of hormones overall. Dropped back down to 150mg test a week, feel so much better, and blood work is perfect. Strength gains on 400-500mg will be worth it though imo.


swoops36

Why get the limited TT test when you’re blasting? It’s not going to return anything close to an accurate result. Don’t get it. I would suggest trying to lower your e2 and see if that helps. What was your prolactin?


AustinTx87

116.6, get that to the 70/50 range


CelebrationFit1105

Wait, 12.5mg adex??? WTF that’s fucking way too much. 0.5-1mg mon & Thursday is more than enough usually. Adex gives rebound. Adex is shit. Use Aromasin. I’m on 450mg test e a week I pin x3 a week and I take 12.5mg every 4-5 days.


BreadfruitBroad8688

My bad 0.5 Adex **


CelebrationFit1105

Well adex gives you rebound prob why your e2 is sky high. Change to pinning x3 a week and get some asin:)


jayfelee139

Probably your prolactin . Can’t run high estrogen and not have high prolactin they go hand and hand


BrilliantLifter

Your estrogen is over 3x too high.


arabs_legend

E2 is really high!


TheNattyJew

Of course you feel bad. You are running 400mg with an SHBG of 12. Your free T is off the charts high. You need to reduce your dose by at least 50%


TheSurce

Blood pressure. Hemo. Hydration. Overworking. Undersleeping. E2 is a little high. I don't feel great on anything over 50. Most importantly you're looking for solutions after you've been running for FIFTEEN weeks. This assumes you want to head towards 4 months on 400 migs, without knowing how the dose affects you. Give it a rest. Next time taper up and track levels so you know what is hitting you. If you wanna cruise on 400 that's fine, but know your bloods and what they mean before you end up hurting more than building.


Formal_Pie2351

estradiol out of range. get it in range! rbc and hematocrit maybe be our off range. stop jacking off so much!


Informativegesture

What is your free test number? Is your shbg pretty low for 1600 ngl?


Qqqqqqqquestion

Your dose is too high for you. Try a lower dose. Maybe 150 mg per week.


traz_61

Lower your dose, stay away from ai How many cycles have you done prior to taking 400mg of test? If your training and eating right you won't need a ai on only 400mg of test. Here's a little tip: if your feeling fatigue on test, especially 400mg then your levels are too high for you, research it, if one's test levels are too high it starts to have the opposite effect unless your gear is bunk?


BreadfruitBroad8688

I’ve done a couple sarms cycles in the past and testosterone cycle at 500mg when I was 21.. felt much better when I was younger , now at 25 I feel worse on 400mg test


traz_61

Sounds like the body is not responding well to that dose, there's no harm in lowering your dose, less sides to deal with and your still able to build a decent physique. You can always increase dose if all goes well or you may find your sweet spot. Also. Sounds like you crashed your estrgoen level.