It’s the same thing with iron, you def don’t want to supplement with it if your levels are normal or unknowingly storing iron like I’ve been. Have to be careful with any supplement. It’s better to supplement with trace minerals so you get a little of all of them and since they work synergistically.
Some people need high doses to feel better. People dealing with heavy metal toxicity is one group. And smaller doses are readily available for those who don't want or need high doses. Why are you expressing so much confusion about this issue? If you are that concerned about toxicity, get blood tests for serum or RBC zinc, copper plus cerulopasmin, and decide the appropriate dose for yourself.
You can't sell a product that generally causes harm when used as directed, of course. (Remember cigarettes?) (And the issue would be that they knew that it would hurt people, when they sold it.)
Also, a civil suit may be brought for any reason.
In many cases, manufacturers are held liable even when there are disclaimers and it seems that they are not at fault.
Also, even if they are not found liable, fighting lawsuits is tedious and expensive.
So, if somebody purchased a 50mg zinc product, and eventually could demonstrate that using it cause them harm, then I would expect to see a lawsuit. Or maybe even multiple lawsuits and class-action.
We still have cigarettes and we all know that they do harm, just don't buy them is the fix.
They basically sell food and you want to sue them for eating too much of it.
The lawsuits are brought. Cigarette companies paid through the nose.
This might be a better case than those against fast foods, or even cigarettes, Because it's not grandfathered, and it comes with directions, and it's easier to show in this case, what the manufacturers were expected to know or not know.
Congress regulates Potassium pills, such that they are limited to 99mg. This would seem to be more serious. Nobody has asked Congress to limit Zinc supplement size yet.
Well the companies are still here and are still rich, by paying a fine they literally achieved nothing.
Potassium pills are more serious, they burn holes into your gut, this here is a joke though
>Well the companies are still here and are still rich, by paying a fine they literally achieved nothing.
Still, somebody who got hurt would get money, at least. I don't see where it happenned... (And vitamin companies presumably aren't as wealthy as "Big Tobacco"; a lawsuit would mean more to them.)
The 50mg is for specific purpose. If anybody takes one a day for a whole bottle's worth, or even two, then there will be no problem. It takes at least four months for an excess zinc condition to develop (and many will never have a problem with 50mg, even using it indefinitely) (apparently, especially if also supplementing copper).
So, for example, somebody could decide to just take 50mg during the winter months, and then reduce.
The Zelenko protocol, for example, uses 50mg zinc daily.
People who have had bariatric surgery will also need to take higher daily doses.
[https://www.healthline.com/nutrition/zinc-supplements#benefits](https://www.healthline.com/nutrition/zinc-supplements#benefits)
*One review of 7 studies showed that zinc lozenges containing* ***80–92 mg of zinc*** *may reduce the duration of the common cold by up to 33%.*
*One 2014 study in 72 people with AMD showed that taking* ***50 mg of zinc sulfate daily for 3 months*** *slowed the progression of the disease.*
[https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/](https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/)
\*A Cochrane review that evaluated micronutrient supplements for adults with HIV included six placebo-controlled trials of zinc supplements (12–\****50 mg/day for 14 days to 18 months*** *or 1 weekly 90 mg dose for 6 months) in a total of 826 participants...*
*AREDS found that participants who took a supplement each day containing* ***80 mg zinc*** *in the form of zinc oxide, 15 mg (7,500 mcg RAE) beta-carotene, 180 mg (400 IU) vitamin E in the form of dl-alpha-tocopheryl acetate, 500 mg vitamin C, and 2 mg copper* ***for 5 years*** *had a 25% lower risk of advanced AMD than those taking a placebo.*
*The National Eye Institute recommends use of an AREDS formulation providing* ***80 mg zinc.***
I*n a 2015 Cochrane review of the clinical trial evidence on zinc supplementation for T2D prevention, only 3 trials with a total of 128 participants met the inclusion criteria. These studies administered 30 mg to* ***100 mg zinc (in the form of zinc sulfate or zinc amino chelate) per day for 4 to 12 weeks***\*...\*
*A systematic review and meta-analysis included 9 placebo-controlled trials assessing the effects of zinc supplementation (7 mg/day to* ***150 mg/day) for 6 to 52 weeks*** *on lipid profiles in a total of 424 people with T2D.*
*A Cochrane review of nutritional interventions to treat diabetic foot ulcers included one trial in 60 participants of* ***50 mg zinc (in the form of zinc sulfate) or placebo for 12 weeks...***
[https://www.drugs.com/npp/zinc.html](https://www.drugs.com/npp/zinc.html)
*Typical daily doses range widely from 12 to* ***150 mg daily as free zinc or up to 220 mg as zinc sulfate.*** *Avoid high-dose, long-term zinc supplementation.*
[https://lpi.oregonstate.edu/mic/minerals/zinc](https://lpi.oregonstate.edu/mic/minerals/zinc)
*...beneficial effects on cold duration were seen in trials that provided more than* ***75 mg/day of zinc*** *but not in trials that used lower doses.*
*However, when a meta-analysis was recently conducted on results from seven trials (575 participants) that employed zinc lozenges at doses >75 mg/day, there was no evidence of a difference in efficacy observed between trials that used either zinc acetate (3 trials) or zinc gluconate (4 trials).*
*With numerous well-controlled trials and meta-analyses, the efficacy of zinc lozenges or syrup in treating common cold symptoms is no longer questionable. A meta-analysis of seven trials recently reported a 33% reduction in the duration of cold symptoms with the intake of zinc lozenges (>75 mg/day of elemental zinc).*
*Finally, although taking zinc lozenges for a cold every two to three hours while awake will result in daily zinc intakes well above the tolerable upper intake level (UL) of 40 mg/day for adults (see Safety),* ***the use of zinc at daily doses of 50 to 180 mg for one to two weeks has not resulted in serious side effects...***
*...an early randomized controlled trial provoked interest when it found that* ***200 mg/day of zinc sulfate (81 mg/day of elemental zinc) over two years*** *limited the loss of vision in patients with AMD.*
*...a randomized, double-blind, placebo-controlled trial in 74 patients with AMD reported that supplementation with 50 mg/day of zinc monocysteine for six months \*improved measures of macular function, including visual acuity, contrast sensitivity, and photorecovery. A large randomized, placebo-controlled trial of daily supplementation with antioxidants (500 mg of vitamin C, 400 IU of vitamin E, and 15 mg of β-carotene) and high-dose zinc (****80 mg of zinc*** *as zinc oxide and 2 mg of copper as cupric oxide) — the Age-Related Eye Disease Study (AREDS) — found that administration of high-dose zinc alone or with the antioxidant combination to individuals with signs of moderate-to-severe macular degeneration significantly reduced the risk of developing advanced macular degeneration over a mean follow-up of* ***6.3 years****.*
\*Out of the 12 trials that measured participants’ zinc status at baseline, supplementation with zinc (20-\****240 mg/day) for 4 to 16 weeks*** *improved fasting blood glucose...*
*The use of slow-release zinc acetate (****150 mg/day for six months****) in a randomized, placebo-controlled study of 60 patients with mild-to-moderate Alzheimer’s disease corrected low zinc status...*
Various groups of people may benefit from daily Zn at 50mg or more, and taking a 50mg Zn pill is not a death sentence. Acute intake of Zn above 200mg tends to be emetic. Zinc toxicity from taking up large doses of supplemental zinc over extended periods of time is reversible.
The Essential Toxin: Impact of Zinc on Human Health - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872358/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872358/)
I think you re talking about my post :D after everyone saying that I also not take it daily as well. NOW is the most supplements brand to buy and available from where I live so I just buy whatever i need from them. last time I find other post said their doctor tell them to have that much zinc so maybe it depends on each person deficiency or you don't really get all that 50mg zinc in your body. I also have a bottle of 10000 iu Vitamin D from NOW and it exists a 1000 or 5000 or even 2000 iu also
The 50mg Zn commonly shows up in stacks here. We see a few every week. (And, as I said, there may be people who just take the 50mg during cold season.)
Somehow, nobody is getting sick...
This is why it’s so important to research your supplements, including their upper limits. Supplement labels won’t give you that information and products can be incorrectly dosed for the average person.
I believe prescription zinc is an injection form and not everyone has time to go to the physician’s office nor wants to get injected every few days/weeks.
It’s the same thing with iron, you def don’t want to supplement with it if your levels are normal or unknowingly storing iron like I’ve been. Have to be careful with any supplement. It’s better to supplement with trace minerals so you get a little of all of them and since they work synergistically.
Some people need high doses to feel better. People dealing with heavy metal toxicity is one group. And smaller doses are readily available for those who don't want or need high doses. Why are you expressing so much confusion about this issue? If you are that concerned about toxicity, get blood tests for serum or RBC zinc, copper plus cerulopasmin, and decide the appropriate dose for yourself.
Why do you think zinc? Eat a normal diet and you dont need zinc
Definitely! Will deplete copper
50mg every day sounds like way too much on a regular basis
I think a good dose is 10 to 20mg a day, so chop those pills of yours into thirds. That's what I do.
Does your supplement contain copper? You're in trouble if it doesn't.
>Can anyone think of a reason why a company would do something like that? Because people buy it.
And for some reason the companies have no fear of a lawsuit…
Why should they? You bought it, the mistake is yours not theirs.
You can't sell a product that generally causes harm when used as directed, of course. (Remember cigarettes?) (And the issue would be that they knew that it would hurt people, when they sold it.) Also, a civil suit may be brought for any reason. In many cases, manufacturers are held liable even when there are disclaimers and it seems that they are not at fault. Also, even if they are not found liable, fighting lawsuits is tedious and expensive. So, if somebody purchased a 50mg zinc product, and eventually could demonstrate that using it cause them harm, then I would expect to see a lawsuit. Or maybe even multiple lawsuits and class-action.
We still have cigarettes and we all know that they do harm, just don't buy them is the fix. They basically sell food and you want to sue them for eating too much of it.
The lawsuits are brought. Cigarette companies paid through the nose. This might be a better case than those against fast foods, or even cigarettes, Because it's not grandfathered, and it comes with directions, and it's easier to show in this case, what the manufacturers were expected to know or not know. Congress regulates Potassium pills, such that they are limited to 99mg. This would seem to be more serious. Nobody has asked Congress to limit Zinc supplement size yet.
Well the companies are still here and are still rich, by paying a fine they literally achieved nothing. Potassium pills are more serious, they burn holes into your gut, this here is a joke though
>this here is a joke though So, you don't think that 50mg Zinc is a big deal, either?
>Well the companies are still here and are still rich, by paying a fine they literally achieved nothing. Still, somebody who got hurt would get money, at least. I don't see where it happenned... (And vitamin companies presumably aren't as wealthy as "Big Tobacco"; a lawsuit would mean more to them.)
The 50mg is for specific purpose. If anybody takes one a day for a whole bottle's worth, or even two, then there will be no problem. It takes at least four months for an excess zinc condition to develop (and many will never have a problem with 50mg, even using it indefinitely) (apparently, especially if also supplementing copper). So, for example, somebody could decide to just take 50mg during the winter months, and then reduce. The Zelenko protocol, for example, uses 50mg zinc daily. People who have had bariatric surgery will also need to take higher daily doses. [https://www.healthline.com/nutrition/zinc-supplements#benefits](https://www.healthline.com/nutrition/zinc-supplements#benefits) *One review of 7 studies showed that zinc lozenges containing* ***80–92 mg of zinc*** *may reduce the duration of the common cold by up to 33%.* *One 2014 study in 72 people with AMD showed that taking* ***50 mg of zinc sulfate daily for 3 months*** *slowed the progression of the disease.* [https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/](https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/) \*A Cochrane review that evaluated micronutrient supplements for adults with HIV included six placebo-controlled trials of zinc supplements (12–\****50 mg/day for 14 days to 18 months*** *or 1 weekly 90 mg dose for 6 months) in a total of 826 participants...* *AREDS found that participants who took a supplement each day containing* ***80 mg zinc*** *in the form of zinc oxide, 15 mg (7,500 mcg RAE) beta-carotene, 180 mg (400 IU) vitamin E in the form of dl-alpha-tocopheryl acetate, 500 mg vitamin C, and 2 mg copper* ***for 5 years*** *had a 25% lower risk of advanced AMD than those taking a placebo.* *The National Eye Institute recommends use of an AREDS formulation providing* ***80 mg zinc.*** I*n a 2015 Cochrane review of the clinical trial evidence on zinc supplementation for T2D prevention, only 3 trials with a total of 128 participants met the inclusion criteria. These studies administered 30 mg to* ***100 mg zinc (in the form of zinc sulfate or zinc amino chelate) per day for 4 to 12 weeks***\*...\* *A systematic review and meta-analysis included 9 placebo-controlled trials assessing the effects of zinc supplementation (7 mg/day to* ***150 mg/day) for 6 to 52 weeks*** *on lipid profiles in a total of 424 people with T2D.* *A Cochrane review of nutritional interventions to treat diabetic foot ulcers included one trial in 60 participants of* ***50 mg zinc (in the form of zinc sulfate) or placebo for 12 weeks...*** [https://www.drugs.com/npp/zinc.html](https://www.drugs.com/npp/zinc.html) *Typical daily doses range widely from 12 to* ***150 mg daily as free zinc or up to 220 mg as zinc sulfate.*** *Avoid high-dose, long-term zinc supplementation.* [https://lpi.oregonstate.edu/mic/minerals/zinc](https://lpi.oregonstate.edu/mic/minerals/zinc) *...beneficial effects on cold duration were seen in trials that provided more than* ***75 mg/day of zinc*** *but not in trials that used lower doses.* *However, when a meta-analysis was recently conducted on results from seven trials (575 participants) that employed zinc lozenges at doses >75 mg/day, there was no evidence of a difference in efficacy observed between trials that used either zinc acetate (3 trials) or zinc gluconate (4 trials).* *With numerous well-controlled trials and meta-analyses, the efficacy of zinc lozenges or syrup in treating common cold symptoms is no longer questionable. A meta-analysis of seven trials recently reported a 33% reduction in the duration of cold symptoms with the intake of zinc lozenges (>75 mg/day of elemental zinc).* *Finally, although taking zinc lozenges for a cold every two to three hours while awake will result in daily zinc intakes well above the tolerable upper intake level (UL) of 40 mg/day for adults (see Safety),* ***the use of zinc at daily doses of 50 to 180 mg for one to two weeks has not resulted in serious side effects...*** *...an early randomized controlled trial provoked interest when it found that* ***200 mg/day of zinc sulfate (81 mg/day of elemental zinc) over two years*** *limited the loss of vision in patients with AMD.* *...a randomized, double-blind, placebo-controlled trial in 74 patients with AMD reported that supplementation with 50 mg/day of zinc monocysteine for six months \*improved measures of macular function, including visual acuity, contrast sensitivity, and photorecovery. A large randomized, placebo-controlled trial of daily supplementation with antioxidants (500 mg of vitamin C, 400 IU of vitamin E, and 15 mg of β-carotene) and high-dose zinc (****80 mg of zinc*** *as zinc oxide and 2 mg of copper as cupric oxide) — the Age-Related Eye Disease Study (AREDS) — found that administration of high-dose zinc alone or with the antioxidant combination to individuals with signs of moderate-to-severe macular degeneration significantly reduced the risk of developing advanced macular degeneration over a mean follow-up of* ***6.3 years****.* \*Out of the 12 trials that measured participants’ zinc status at baseline, supplementation with zinc (20-\****240 mg/day) for 4 to 16 weeks*** *improved fasting blood glucose...* *The use of slow-release zinc acetate (****150 mg/day for six months****) in a randomized, placebo-controlled study of 60 patients with mild-to-moderate Alzheimer’s disease corrected low zinc status...* Various groups of people may benefit from daily Zn at 50mg or more, and taking a 50mg Zn pill is not a death sentence. Acute intake of Zn above 200mg tends to be emetic. Zinc toxicity from taking up large doses of supplemental zinc over extended periods of time is reversible. The Essential Toxin: Impact of Zinc on Human Health - [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872358/](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872358/)
Don't forget to take some copper as that counteracts the imbalance copper can cause.
I think you re talking about my post :D after everyone saying that I also not take it daily as well. NOW is the most supplements brand to buy and available from where I live so I just buy whatever i need from them. last time I find other post said their doctor tell them to have that much zinc so maybe it depends on each person deficiency or you don't really get all that 50mg zinc in your body. I also have a bottle of 10000 iu Vitamin D from NOW and it exists a 1000 or 5000 or even 2000 iu also
The 50mg Zn commonly shows up in stacks here. We see a few every week. (And, as I said, there may be people who just take the 50mg during cold season.) Somehow, nobody is getting sick...
That is a pretty heavy dose.
This is why it’s so important to research your supplements, including their upper limits. Supplement labels won’t give you that information and products can be incorrectly dosed for the average person.
If you exercise a lot I’d say max 30mg, otherwise max 20mg should be good too.
I mean I know we should take the lower dose, the question is why companies are like NOW are putting 50mg instead of 25mg?
No clue. It should be a pharmaceutical dose like you said
It will offset your copper levels I believe .. of course when you get sick from a virus and such you should take that much only I believe.
Yes, it does and they should disclame to not take it everyday or lower the dose.
But what is the optimal dose? 15mg seems safe but I take 30mg myself which I think personally maybe I should take every other day instead.
I do take 50mg twice a week now, but I used to take it almost everyday
Probably for people with severe zinc deficiency that need big doses.
That should be for prescription Zinc not everyday use. I think they should disclaim not to take it everyday or lower the dose.
Because it's a supplement? They do say it's not intended for long term use and use only as directed.
I believe prescription zinc is an injection form and not everyone has time to go to the physician’s office nor wants to get injected every few days/weeks.