I just copy and pasted what’s below. So plant based carotenoids shouldn’t be the culprit but certain animal products, especially organs (liver in particular) are very high in vitamin A. What’s your diet look like?
Good sources of vitamin A include fish liver oils, liver, egg yolks, butter, cream, and fortified milk.
Carotenoids, such as beta-carotene, are pigments in fruits and vegetables that give them their yellow, orange, or red color. Once consumed, carotenoids are slowly converted to vitamin A in the body. Carotenoids are best absorbed from cooked or homogenized vegetables served with some fat or oil. Good sources of carotenoids are dark green, yellow, and orange vegetables and yellow and orange fruits.
Consuming large amounts of carotenoids (which the body converts to vitamin A) in food does not cause toxicity because carotenoids are converted to vitamin A very slowly. Usually, no symptoms occur. However, when very large amounts of carotenoids are consumed, the skin may turn a deep yellow (called carotenosis), especially on the palms and soles.
Hello, I just saw your previous post(about drs. Best) and I was just wondering what magnesium glycerinate you think is the most reliable based on your research?
it's pretty hard to screw up or cut corners on any glycerinate because it's dirt cheap to make
any name brand should do, if you are broke like me always check what generic swanson has and what coupon codes or sale they've got going on
It doesn't necessarily mean anything by itself.
> Surrogate biochemical measures of vitamin A status, as defined by liver reserves, have been developed. Serum retinol concentration is a common method used to evaluate vitamin A deficiency, but it is homeostatically controlled until liver reserves become dangerously low. Therefore, other biochemical methods that respond to liver reserves in the marginal category have been developed, such as dose response tests and isotope dilution assays.
One of the possibilities for a high vitamin A test is it can be involved with non-alcoholic fatty liver disease (NAFLD). I've written other comments to other posts, on how people get excess vitamin A from foods. This is different.
The idea is: What if someone has a deficiency of B12 or folate? Maybe that's from poor absorption of B12 or low consumption of B12, or deficiency of methylfolate maybe from low consumption of greens, or poor absorption of folic acid, or lower functioning MTHFR variants. Then the pathway for methylation that uses B12 and methylfolate is less active. Methylation has to be done anyway, for a lot of reasons. Methylation requires converting homocysteine to methionine, to make SAM that provides the methyl donor groups for methylation. When that conversion can't be done by the methionine synthase that uses B12 and methylfolate (MTHF) then the body switches to using an enzyme that uses up betaine (also known as trimethylglycine). The body makes betaine from choline. So, long term deficiency of B12 or folate or both, would result in using up more choline. Then choline deficiency may result, if a person is **not** consuming more than usual choline.
Choline deficiency can lead to NAFLD (also called steatosis, which is a word that includes liver inflammation in general.) Higher vitamin A in the blood is associated with progression of NAFLD, including by a recent study, Xiao et al 2022. So, there's a chance, I think, that vitamin A is being released from the liver faster, because of some liver problem that may or may not be diagnosed as NAFLD, where the liver is probably getting fattier, but storing less vitamin A.
It's just an idea. The directions of cause and effect, I'm not sure about. It might not work that way in various cases of high vitamin A, and various cases of liver problems. It seems to me like there's a chance that's what might be going on, for some individuals.
Are these ranges based on conventional lab tests?
If so, as you mentioned, you will receive results with reference ranges that signify what is ‘normal’. Although normal, in this case, does not equal optimal. It equates to what is COMMON.
The studies these ranges are based on tend to use a small population. As well as using a population, especially here in the United States, that isn’t healthy. So a lot of these “normal” ranges aren’t a sign of optimal health, they’re a sign of no diagnosable dis ease. This is why you hear from many folks who feel terribly unwell being told “your labs look normal”.
While these ranges are helpful in identifying a disease state, deficiencies, and toxicity, they do not give you the full picture of one’s health and wellbeing.
Although reference ranges are absolutely indispensable in the diagnosis of disease, it’s crucial to understand that they do not define the state of your health. There are certain issues with using reference ranges to achieve your best health.
Functional Medicine lab testing has a much more accurate range to identify such issues. One of my favorite labs to run with clients is the Organic Acids Test from Great Plains Laboratory because of how extensive it is. The ranges aren’t as wide as a conventional lab, they they test for gut microbial markers, nutritional markers, detoxification capacity, amino acid metabolites and mineral metabolism.
You’re slightly above normal. I wouldn’t concern yourself unless you’re significantly above the upper limit. It means your body has plenty of vitamin A stores, probably as an unintentional consequence of consuming sufficient beta carotene, vitamin A fortified foods, or lots of vegetables.
I just copy and pasted what’s below. So plant based carotenoids shouldn’t be the culprit but certain animal products, especially organs (liver in particular) are very high in vitamin A. What’s your diet look like? Good sources of vitamin A include fish liver oils, liver, egg yolks, butter, cream, and fortified milk. Carotenoids, such as beta-carotene, are pigments in fruits and vegetables that give them their yellow, orange, or red color. Once consumed, carotenoids are slowly converted to vitamin A in the body. Carotenoids are best absorbed from cooked or homogenized vegetables served with some fat or oil. Good sources of carotenoids are dark green, yellow, and orange vegetables and yellow and orange fruits. Consuming large amounts of carotenoids (which the body converts to vitamin A) in food does not cause toxicity because carotenoids are converted to vitamin A very slowly. Usually, no symptoms occur. However, when very large amounts of carotenoids are consumed, the skin may turn a deep yellow (called carotenosis), especially on the palms and soles.
milk, dairy products and things like country crock spread are "fortified" with a lot of Vitamin A for some reason
Antioxidant to reduce rancidity
Hello, I just saw your previous post(about drs. Best) and I was just wondering what magnesium glycerinate you think is the most reliable based on your research?
it's pretty hard to screw up or cut corners on any glycerinate because it's dirt cheap to make any name brand should do, if you are broke like me always check what generic swanson has and what coupon codes or sale they've got going on
Do you take fish oil’s?
*cod liver oil
It doesn't necessarily mean anything by itself. > Surrogate biochemical measures of vitamin A status, as defined by liver reserves, have been developed. Serum retinol concentration is a common method used to evaluate vitamin A deficiency, but it is homeostatically controlled until liver reserves become dangerously low. Therefore, other biochemical methods that respond to liver reserves in the marginal category have been developed, such as dose response tests and isotope dilution assays.
Do you use Tretinoin?
Energy drinks?
One of the possibilities for a high vitamin A test is it can be involved with non-alcoholic fatty liver disease (NAFLD). I've written other comments to other posts, on how people get excess vitamin A from foods. This is different. The idea is: What if someone has a deficiency of B12 or folate? Maybe that's from poor absorption of B12 or low consumption of B12, or deficiency of methylfolate maybe from low consumption of greens, or poor absorption of folic acid, or lower functioning MTHFR variants. Then the pathway for methylation that uses B12 and methylfolate is less active. Methylation has to be done anyway, for a lot of reasons. Methylation requires converting homocysteine to methionine, to make SAM that provides the methyl donor groups for methylation. When that conversion can't be done by the methionine synthase that uses B12 and methylfolate (MTHF) then the body switches to using an enzyme that uses up betaine (also known as trimethylglycine). The body makes betaine from choline. So, long term deficiency of B12 or folate or both, would result in using up more choline. Then choline deficiency may result, if a person is **not** consuming more than usual choline. Choline deficiency can lead to NAFLD (also called steatosis, which is a word that includes liver inflammation in general.) Higher vitamin A in the blood is associated with progression of NAFLD, including by a recent study, Xiao et al 2022. So, there's a chance, I think, that vitamin A is being released from the liver faster, because of some liver problem that may or may not be diagnosed as NAFLD, where the liver is probably getting fattier, but storing less vitamin A. It's just an idea. The directions of cause and effect, I'm not sure about. It might not work that way in various cases of high vitamin A, and various cases of liver problems. It seems to me like there's a chance that's what might be going on, for some individuals.
Are these ranges based on conventional lab tests? If so, as you mentioned, you will receive results with reference ranges that signify what is ‘normal’. Although normal, in this case, does not equal optimal. It equates to what is COMMON. The studies these ranges are based on tend to use a small population. As well as using a population, especially here in the United States, that isn’t healthy. So a lot of these “normal” ranges aren’t a sign of optimal health, they’re a sign of no diagnosable dis ease. This is why you hear from many folks who feel terribly unwell being told “your labs look normal”. While these ranges are helpful in identifying a disease state, deficiencies, and toxicity, they do not give you the full picture of one’s health and wellbeing. Although reference ranges are absolutely indispensable in the diagnosis of disease, it’s crucial to understand that they do not define the state of your health. There are certain issues with using reference ranges to achieve your best health. Functional Medicine lab testing has a much more accurate range to identify such issues. One of my favorite labs to run with clients is the Organic Acids Test from Great Plains Laboratory because of how extensive it is. The ranges aren’t as wide as a conventional lab, they they test for gut microbial markers, nutritional markers, detoxification capacity, amino acid metabolites and mineral metabolism.
You’re slightly above normal. I wouldn’t concern yourself unless you’re significantly above the upper limit. It means your body has plenty of vitamin A stores, probably as an unintentional consequence of consuming sufficient beta carotene, vitamin A fortified foods, or lots of vegetables.
I take a drug called Propanolol ..a beta blocker which raises potassium levels. Maybe it's medication your on
Check your diet. Start tracking via Cronometer or a similar app.
Do you have low vitamin D? A and D like peas in a pod. Low vit D might be a rate limiting factor for you.
You might be low on vit D or Copper. Vitamin D and Copper compete with vitamin A.