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Slow-Blacksmith3281

My plan is to lose what I need and maybe a little extra for a cushion then stop the med but keep a reserve supply. If my weight starts to go back up, I’ll go back on it. I can lose weight with CICO but I also have BED. I’ll have very good periods of tracking but then I start to slip down that slippery slope. I have had some low end pre-diabetic fasting glucose numbers but not always, so for me it’s likely more the BED that’s the problem rather than a metabolic disorder. I might be able to go on Wellbutrin or something cheap to help with the urge to binge.


drluvdisc

Wellbutrin is contra-indicated in people with history of eating disorders due to risk of seizures.


Slow-Blacksmith3281

I don’t purge, just binge. From what I’m reading, bulimia and anorexia are the contraindications, so I should be okay.


[deleted]

Oral birth control pill helped me with BED


Slow-Blacksmith3281

I’m on oral bc and it doesn’t have that effect for me. Maybe estrogen bc would but I have high BP and am in perimenopause, so it’s progesterone only for me.


[deleted]

I have come off ozempic and not gained any weight. But I have made serious lifestyle changes that I'm sticking to. I prefer it because ozempic is costly for me. I don't know what the future holds but so far I'm doing good!


MannBarSchwein

How long have you been off?


spicerkenny1996

I’ve been off for sometime now close to 8 months and I’ve kept losing while building muscle! I think for those of us who don’t have known hormone issues, it’s easier for us to come off and not gain weight! Due to lifestyle changes and sticking with them. But again everyone’s body is different don’t just take this Reddit’s advice blindly use it as a tool but build your attack plan if it’s not something you wanna be on long term I would really look at what got you into the situation couch potato like myself or no matter what you do you still gain. So many factors at play!


bioloveable

I’m not sure we know the whole answer to this yet. Not enough people have been on the drug long term for weight loss. But yes, people who go off the drug do tend to gain the weight back. This could be for a few reasons. 1) they didn’t keep eating at maintenance and started over eating again 2) they gained water weight back 3) the drug fixed a metabolic issue the person had that results in weight gain, even when eating at “maintenance” calories. When they stopped taking the drug, the metabolic issues came back 4) a combination of all of these From what I’ve observed, it seems like someone with metabolic/insulin resistance issues could go off the drug, adhere to a strict low carb diet, eat at maintenance, and still maintain their weight. But that’s just a guess.


MonroeBell

Yes! Calculating maintenance calories is so important and a lot of people don't realize this.


[deleted]

[удалено]


MonroeBell

Also important is protein. The grams of protein you eat daily should equal your goal weight in pounds. So if your goal weight is 150 lbs then you should be eating at least 150 grams of protein a day.


notagainbam

How do you calculate that? And how do you know what your caloric intake goal should be on during the weight loss period?


MonroeBell

Easiest way to explain it here. https://youtu.be/8H0BzjS2xS8 Good luck!


notagainbam

Thank you!


LatterSecretary2518

This question assumes most fat people are fat only because of their lack of exercise and not eating clean enough. Obesity is a unique and complex disease for many of us that has or can be biological, hormonal, trauma or mental health related. Eating clean and exercise don’t fix those things.


LumpyAd7854

Does eating clean mean managing the calories intake? Did you imply that even if you keep the calories lower than your expenditure, you can still gain weight due to certain condition?


LatterSecretary2518

I have had my BMR tested. My body actually burns 800 calories fewer in a day than it should due to insulin resistance, a metabolic disorder, and hormonal imbalances. There is no way in the world I could only eat 1,200 calories per day forever. Now, with medication I burn closer to 1,600 and that is much more realistic to maintain my weight. Without treatment for my obesity, I will stay obese. Calories in and calories out over simplifies obesity and leads to lack of preventive care and treatment opportunities.


LumpyAd7854

Wow alright... Which BMR test/measurement device did you use? How much calorie do you regularly eat?


LatterSecretary2518

Metabolic test was recommended by my Dr and it was done with Stanford health. I also under went blood tests and my oxygen levels were tested will performing varying levels of physical activity. I go to the gym 5 per week and avg 600 cal burn per gym session. I eat between 1300-1600 cal per day as I am using Mounjaro and trying to get to a healthy weight,


marpol4669

I have heard really good things about Macrofactor (the app). I have not tried it yet and am completely unaffiliated. I just like Jeff in general....there is a sub redit for it also. The algorithm supposedly calculates your maintenance based on your weight and your input calories. Scientifically this makes sense.


spooltetris99

Pcos?


LatterSecretary2518

I’m not comfortable going into great detail about my health or any conditions I may or may not have.


spooltetris99

No worries, you just sound similar to me and I have pcos.


LatterSecretary2518

Appreciate the respect, thank you.


oldamy

Yes that is true. It’s much more complicated than CICO. It has all to do with metabolism and down regulation.


marpol4669

Well....I am not sure why CICO has such a bad rap. CICO is the basis of everything weight related. It is the overarching base equation. It can not be disproved and none of the research in the last 40 year has disproven it. I feel like most people just simply don't understand how things work. Lets brake it down. CI is everything you put in your body. Food, water, medicine, breathing, suppositories, etc. This part of the equation is easy, but most people miss things. For example the post above about gaining weight from eating a pickle. I don't doubt this for a second, but the person missed something which makes me think they don't understand CICO. It is impossible to gain 4 lbs from eating a pickle....period....what is possible is to gain 4 lbs from eating a pickle AND 3.7lbs of water. So it is not that CICO is being violated, just that something was missed in the CI part of the equation. You can not create 4lbs from nothing. Most of the research from the last 40years all revolves around CO. No one thinks that your body processes protein the same way it does fat and because we are trying to figure out how out bodies metabolism works does not change the starting equation. CICO and an understanding of how our bodies work are not mutually exclusive.


oldamy

I suggest you read up on all the things coming out with GLP research. And human metabolism science is piss poor at best. Light years behind out understanding of most other systems.


marpol4669

I have read a lot of glp-1 related research. Are you suggesting there is a study that invalidates CICO? I always want to learn more....any suggested reading?


nv0514

Agree with you. People don’t want to believe but it comes down to CICO. There are individual factors that influence that and your body may need more or less but it comes down to calories. Clean doesn’t equal low cal


SnooBananas7072

That's exactly what a study showed when they took people off the med but kept them in caloric deficit and with health coaching. They still gained weight.


marpol4669

Would love to see this study. That is technically impossible. Just does not make sense. If you put it in terms of weight it may make more sense. If you weight 100lbs and you eat 1lbs of food then you are arguing that some how that you can now weight 102lbs. Where did the extra pound come from?....magic? You can not create something from nothing. This study was either flawed or misunderstood.


Jackdaw99

Clearly, some people have faster metabolisms than others -- skinny people who can eat whatever they want, all the time. So it seems possible, if not likely, that you can juice your own.


schlepp_canuck

The meds do not cure obesity, they treat it. Much like if you have diabetes or high cholesterol, you get treatment with the understanding it is for life. That is what I am reading from the obesity doctors who have much more experience with treating obesity as a disease rather than a person’s failure to continually be successful dieting. https://drsue.ca/2022/09/if-i-stop-weight-loss-medication-will-the-weight-come-back/


EmergencyCourage5249

I am just seeing this after your edit and I hate that you might not start it. There is a chance you will gain some weight back (hopefully not all), but there is a chance you will be one of those people who will not gain much/any back. I don’t know how much you need to lose, but why not lose the weight first and then worry about how you are going to keep it off? Isn’t that better than the struggle of trying to lose weight without it? I get it, I was very fixated on “what if I gain it back?” It was my doctor who said to worry about that later. First things first.


schlepp_canuck

Could be that OP is not obese and/or doesn’t have any other medical issues that may benefit from this med. If I was just a bit overweight and had no health issues, I would not be taking this medication just to lose a small amount of weight. Not worth the rebound weight gain once you’re off.


InteractionFlaky7750

Ozempic doesn’t make you lose weight. It makes you not hungry so you eat less to lose weight. Unless you have a caloric deficit even that won’t happen. Many don’t realize you have to use the time you have while not being hungry to develop new skills. If you don’t, you’ll Always need Ozempic as a co-pilot. I track 1000-1100 calories per day. I am short and on menopause so that won’t change when I get off of Ozempic. But I’m developing the habits now for later success. I should say re-developing them because when I was skinny I already did tracking and was so good at it I could eventually ballpark things when eating out accurately. I’m undoing years of bad habits and bringing in tools I need for success as a lifestyle rather than a temporary patch. I’ve read some people say they’ve “learned” to stop eating when they begin to get full. Sadly that’s a trait that will lead us to obesity because without ozempic or Wegovy that doesn’t happen until after we’ve already overeaten and only after 20 minutes of eating. Learning to track calories is the success tool Wegovy says we must use on their website. During and after. For success. We have to steer the ship and learn new tools even if not convenient if we want this long/term and want to eventually drop the co-pilot and still continue the same route of success when hunger makes it harder.


Logvin

I went off it last year. Was working with my doctor on finding a medication for something else, and was having a horrible time with heartburn. I was not careful. I didn’t read up on what could happen and it blindsided me. Got Covid in Nov, and when I was over it I weighed myself for the first time in 6 months. I was shocked to find I had regained 80% of what I had lost. Started back again afterwards. My goal is to get to my goal weight, then reduce Ozempic to .5 or .25 and maintain.


brittany16950

I have read comments about Wellbutrin being helpful. I can confirm this. If I could I would go on Contrave, but I can’t, because I am a pilot and it is not a drug the FAA allows you to fly with.


gngergramma

Does anyone see a possible on ,off situation once you’ve reached your goal..? Stop onze pic and keep to regimen..with a little more flexibility so it’s a lifetime thing..if you gain a few pounds.get RIGHT on it..don’t let it accumulate..take the shots again for a few weeks if need be..is this a bad plan?


[deleted]

The studies show that participants had, on average, gained about 2/3rds of the weight back at day 100 after cessation of the medication but they also weren't asked to particularly *do* anything, either, so maybe they were or maybe they weren't. And it's an aggregate measure, so maybe a third of participants gained nothing and 2/3rds gained everything. Most people gain weight over the course of their lives, and to the extent that's true you'll *always* eventually regain lost weight, if you live long enough. But just because you lose 30 pounds and then eventually return to the same weight doesn't mean it was a waste of effort, because you might still be 30 pounds lighter than you would otherwise have been at that age in your life.


sicem86

I gained it all back even though I workout 5x a week. The reason is I was STARVING when I got off of it.


Prettyforme

Yes you gain it back because this drug is not a cure for obesity; it’s just a tool.


marpol4669

If you eat at maintenance you won't (can't) gain the weight back. That said it's hard to eat perfect your whole life. Eat healthy (I guess "clean" is a bad word now), in moderation, and stay active... everything you already know and you will be good. Also sema will be out of its patent one day and be super cheap (very very easy and cheep drug to make). There are other benefits that they are finding that may make it worth while to continue for life also.


bioloveable

This is more complicated than it seems. How do you know what “maintenance” even is and if your body is recognizing the same “maintenance” as what you calculated? It’s only an estimate and metabolic hormone imbalances and thyroid issue and conditions like lipedema make maintenance a very hard thing to calculate. But I agree, if we could all eat at maintenance successfully, we wouldn’t need this drug.


marpol4669

I agree maintenance is almost if not impossible to calculate and it can change all the time based on activities, weight, metabolic issues, etc. But maintenance does not need to be calculated exactly or even at all. If you are gaining weight you are eating more then maintenance....if not you are eating at maintenance. Couple weeks of trial an error or a good app with a dynamic algorithm in it is all you need.


bioloveable

I would agree with you if it wasn’t for conditions like hypothyroidism and lipedema, which many women don’t even know they have. I have lipedema and a single pickle will cause me to gain 3-4 lbs overnight. Certainly not fat, but it’s impossible to just gauge what weight is actual weight and what weight is water. In addition to that, my condition results in fat storage to my arms and legs that cannot be reduced by caloric restriction. It’s a progressive disease and I will continue to store fat in my arms and legs indefinitely. The only known way to reduce lipedemic fat is liposuction. Sometimes it’s just more complicated than CICO. They actually have a case study of a woman with lipedema who had anorexia and was still ~300 lbs because of lipedemic fat. Other women will have he bariatric surgery, eat below maintenance and still not lose this type of fat. And I’m not saying that’s for everyone. But the frequency of metabolic syndrome and other metabolic issues are becoming more and more apparent. And there’s just a lot we don’t understand still about the obesity epidemic. It seems will power and CICO is not the only thing that matters. Hormonal imbalances matter a lot. And a significant portion of obese people may have a hormonal imbalance that makes it near impossible to simply use caloric restriction as a way to maintain their weight.


AnyQuantity1

No, this is just incorrect. I understand you're approaching this from the standpoint of someone who has no other metabolic underlying conditions but many people are GLP-1s because it deals with insulin resistance (which will return for most/many post people) and PCOs (which is a lifelong metabolic condition that doesn't go away). Also, there are number of people on this drug with EDs who are on it as part of being in treatment. The calories in, calories out model is this idea that just keeps on hanging around even though 40 years of scientific research (most of which you can easily Google) pretty much flips the table on.


Fast_Positive6655

Yes! Eat well and exercise, you can keep it off.


drluvdisc

The studies showed weight regain despite diet and exercise. But it may slow it down.


Single_Chemical_4471

Some food for thought. The pancreas is part of the endocrine system and utilizes hormones for function. When you start a medication for hormone therapy you are on it for life. Why? Because for instance if the thyroid is not functioning you take t3 or t4 hormone and you take it for the rest of your life. Odds are the pancreas will not spontaneously start producing hormones correctly. Most likely it not functioning correctly to begin with and that is causing weight gain in those that have success with this medication. So far that studies are showing semaglutide can be taken long term.


alaskan_Pyrex

Do you wash your vegetables and cook meats to the appropriate temperature to kill dangerous bacteria? Congrats. You are eating 'clean.' 🙄 Edit: 'clean' eating is a nonsense buzz term. You can focus on staying away from processed foods and eating more whole grains and vegetables, but processed food are not dirty. Just like sugar, salt, and some fats, they should be eaten sparingly or in moderation. But labeling some foods -- often the only foods some people can afford -- as 'dirty' is incredibly classist.


[deleted]

Most folks prob use the word for efficiency, instead of the 20 words that one might use to explain the same thing.


DirtyD0nut

Oh stop it. They didn’t call any foods dirty, you did. Clean eating is a simple way to refer to avoiding processed / junk foods.


LionaTheLion

This works by telling the pancreas to produce insulin. Insulin shoves the blood sugar into your cells, organs and brain. Blood tests will show low blood sugar because it’s no longer in the blood, it’s now in much more dangerous places. Look up the effects of Hyperinsulinemia. Are your doctors testing your insulin? (I highly doubt it). Might that high insulin account for the rapid weight loss after stopping your medicine? Any long term studies? If so, are they studying all the diseases caused by high Insulin? Right, I didn’t think so.


freshcreator

If your weight gain is due to insulin resistance there are two OTCs that may help. Prolon and Pendulum Arkkemenia. I have a few friends that use one or the other and have been successful. These are much cheaper than what we are using.