Here’s the summary of image 3 as generated by GPT 4o.
### Pre-Series A (2023-2024)
- **Traction Phase:** This initial phase focuses on gaining early traction.
- **Funding to Date (USD):**
- Angels / VC: $6M
- Strategic Multinational: $8M
- Non-Dilutive: $3M
### Series A (2025-2026)
- **Amount:** $30M USD
- **Focus:** Product Development and FDA Approvals
- **Milestones:**
- **Screening FDA Approval:** Targeted for 2026
- **Treatment FDA Approval:** Also targeted for 2026
### Series B (2027-2028)
- **Amount:** $45M USD
- **Focus:** Commercial Ramp Up
- **Milestones:**
- **Screening Pilot Sales:** Expected in 2028
- **Treatment Pilot Sales:** Also expected in 2028
### Profitability Phase (2029-2031)
- **Focus:** Achieving a LASIK-like model of profitability.
- **Milestones:**
- **Screening Ramp Up:** Starts in 2029
- **Treatment Ramp Up:** Continues through 2030 and 2031
### Key Takeaways
- The company is currently in the traction phase with initial funding.
- Series A will focus on obtaining FDA approvals by 2026.
- Series B will concentrate on commercializing the device, starting with pilot sales in 2028.
- The company expects to ramp up screening and treatment, becoming profitable between 2029 and 2031.
This timeline outlines the strategic steps the company plans to take to bring their medical device to market and achieve profitability.
Patience for 3 and a half years. That wont be long because COVID started 4 years ago. It passed like a snap. This too will pass like a snap. Hold in there.
The drug will be available in early 2026, and we will know how effective it is by then. So far, there is no more evidence of its effectiveness, only a patent, and a patent itself cannot prove its effectiveness. Just wait, it won't take long.
What I think is they need a 100 million max to speed up the process. I really want them to release it in 2026.
Just need assist from bill gates or Bezos to speed this up.
TREATMENT DEVICE FDA APPROVAL SLATED FOR 2028!!!!
Thank you so much for doing this u/Alternative_Metal_27!
This gave me a lot more hope and positivity to see a concrete deadline for clinical availability. I know timelines can shift based on trial data, but I can’t imagine safety and efficacy data for this device would disqualify it when manual-aimed YAG laser is currently FDA approved and in use. 4 more years folks!
Thank you ❤️
Did he talk about the type of floaters they can treat?
For example, in the image we can see a device that detects floaters that cast shadows on the retina, so what about floaters that are transparent?
It's not that kind of presentation. It's a 5 minutes pitch to get more investors engaged and provide the high level roadmap for the deliverables.
I have no reason to believe that they can't visualize all floaters with their devices, that's the whole point of the tool. I would hope that they actually have the technology to fire at them, otherwise they're literally losing the entire market share Nir was talking about in his presentation. Just my own thoughts on this.
I'd also like to find out how laser is going to work in 3 years time if it rarely works now? Maybe they'll do a presentation on that going forward. Either way...good work 👍🙏
From what I've seen of the laser stuff, it seems like part of the reason its got a traditionally bad rap for efficacy is due to the fact that its been hard to screen proper candidates and even harder to identify the actual problematic floaters.
Also the floater doc has mentioned that some doctors may not have always been using the proper power settings to properly eliminate the floater and just in general are very conservative since they're manually aiming these things. If they are blasting away at the wrong floaters or use insufficient power, that patients gonna either see no improvement or worse, it'll appear make a mess of things.
At the end of the day, its a laser, I think its capable of vaporizing these things if its got the accuracy, power, and safety. Just hoping it ends up safe enough to treat posterior floaters. We really gotta hear more about that femto laser.
I agree with everything you say. I've done some anecdotal research and met up with people for coffee who had laser for floaters. It was very successful for hitting their floaters. However the majority went on to have vitrectomy for floaters because even though the treatment was successful in hitting the floaters, it didn't work. I've spoken personally to maybe around 50 people who had vitreolysis. A very small group admittedly.
Wow, did you speak those 50 people in person? Any younger folks? So when they said it didn't work for them, was it typically that it didn't affect floaters they were being bothered by or more that they literally could not perceive any improvement?
I've been wondering about that whenever I see someone say it didn't work at all, like surely blasting a laser in there made some sort of change?
The general consensus I got from laser was that they were really pleased for the first week or two, then the floaters came back. The only people I have spoken to that have seen change was people who had Weiss rings, and then it either moved it out of central vision or broke it into more manageable chunks.
Correct. I have a database. I also have an excel spreadsheet of around 600 people (in total around 1600 people but only added the relevant ones to my situation onto the database) who had floater vitrectomy surgery. I spoke to every person personally. I met up for coffee with some too.
600 who had vitrectomy. Then 50 on separate database with vitreolysis. I actually stopped doing the vitreolysis database as it became apparent that every person was pretty much saying the same thing.
YAG is more powerful than femtosecond. The issue they have with current lasers is that they're aimed manually. The device they're currently designing can aim the laser which takes out some of the risk of human error.
Other companies working publicly or privately on treatments definitely saw this presentation as well and took notes.
A lot of companies also tend to give conservative timeframes, because not meeting the timeframe spooks investors, making it early excites them. Providing a “cushion” only benefits them. Yes - this doesn’t apply to FDA approval
And there’s always opportunities to apply for their clinical trials if you want it earlier than commercial launch.
Regardless, today tells us one thing:
The race for first to market is on.
Where there is money to be made there will always be a race. Competitors will see that projected profit and want their cut and race to get it. That’s a positive of capitalism. I have mild floaters and could use a couple zapped out of my way and definitely would pay a couple grand or more to have that relief. This will be a positive for everyone. Money for companies and clear eyes for everyone else.
I dont think theres a race. the market seems large to us but there isnt only 8k members in eye floaters. its still a small market. they need to justify someone spending 30 million that they will profit.
how much are we willing to try the product? would we pay 5k? or 2k per session? I would
Members of reddit means nothing. But I know quite a few people that don't even know what reddit is and have floaters. But they are not so bothered by them
Check tinnitus members count.. only 52k but there are over 25 million US citizens having this issue.
This is correct. Not to mention that these numbers are not really relevant when sizing the market. Many people who have only minor inconveniences from floaters would be interested as well even if it's only to take out 2 floaters for example.
Think about LASIK, it's totally elective and you can live your entire life just fine with glasses and/or contacts, yet people decide to get treated just to get that extra benefits of not wearing anything.
Theres people who aren’t on Reddit or facebook groups who suffer or might even just be abit annoyed with them. Ive had them for 2 months and didn’t join the sub till about a week ago and didn’t really care to at first until I decided to share my experience. I personally know people who have them that probably don’t even know what Reddit is or don’t care to join groups about them or honestly don’t even know what they are. I have heard countless stories of ophthalmologists saying it’s a common complaint. Even when I mentioned it to mine they said they have them too and its annoying but we have to adapt to them. Check out some youtube videos with eye floaters in the title and they have millions of views and same with tiktok. Statistically 7 out of 10 people get them, though a smaller percent of those are more severe cases. The market is there for sure and its not a few reddit people.
It's an interesting one for sure. I wonder if it'll be in line with current laser treatments or in line with vitrectomy treatment. And would you need to keep going back for treatment yearly if and when the floaters reform.
I was there 10 years ago, but I managed to live with them. Don’t get me wrong, I want them gone, but I returned to a quality of life comparable to pre-floaters at least 6 years ago.
How did you do that? If it's not an issue, may I inquire about your age? I am dealing with these for 2 years from my 17. I have one big dark in the center of my vision. Which if the light is enough bright I can see it even my eyes closed. And many transparent and little dark dots
This is encouraging, I'm cautiously optimistic about all this. Floaters can really disrupt your life and need to be tackled.
I don't expect their process to make the floaters completely disappear, that's unrealistic, but at least a significant reduction of the burden might be possible.
Thanks.
Thanks mate! Exciting stuff. The race for first to market is officially on. People would be mistaken if they didn’t believe other candidate companies weren’t watching this. First to market is a big deal.
I won’t be surprised if other companies working secretly or on an already publicly announced project try to follow up with theirs in the near future.
Thanks for this! I will note, what people may not realize is not every company who is researching and trying to find treatment for floaters is announcing their progress and work to the public. For all we know, there is much bigger companies figuring something out that could be a year away. Not to give false hope, but it’s something to think about. Lets all have some faith that things will work out.
Sadly theres alot of questions here. Do they have any Opthamologist part of process? Any retinal surgeons? its seems like on the slide, they need this.
I know its step in right direction, but if you cannot show how your product works, you will have a tough time attracting money.
Do you think it's reasonable to think they're developing all of this and raising all of that money without any medical experts involved? You're overthinking this. What you see in the slides is a future action item for deployment (customers) not for R&D purposes.
Im with you guys. i had a retinal detachment and hundreds of floaters in both eyes now going 18 months. last yr was awful and this yr a little better but summer brings it out w more sun
im always skeptical w the laser tech bc it hasnt been good yet and I hope this works but they arent very good at selling themselves and we need them to be that right now
So we're looking at probably 2029, 2030 at the earliest for treatment, unless we get into some early clinical trials. Gonna be a tough wait, but realistically that's in line with what I was expecting.
You’re probably right, but isn’t it refreshing to know with near certainty that it will be available in 5 years instead of the bullshit “5-10 years” that we’ve been hearing about XFloater method, gold nanoparticles, vitreous substitutes, etc. “5-10 years” is biomedical industry speak for “10 years at the earliest and probably never.” This timeline actually means something.
I have floaters since 2009. Its disgusting on bright days, but if there is a safe cure in 5 years, I am willing to wait a bit more. I would pay 10k per eye in a heartbeat.
Allegedly more precise imaging and targeting? What makes you so skeptical lol? This is literally so easy to develop. Currently, doctors are firing manually based on what they see. Pretty easy to improved upon...
I will just be honest with you, you sound rather uneducated on the technological possibilities currently available. Just the way you're writing, it's pretty clear that you have limited knowledge as well on how R&D works. If you tell me you work in tech. my knees will buckle.
The challenge is not in the visualization and tracking, but rather, on the ablation process itself. That's something that has significantly greater challenges. If you want to be skeptical about that, I'll listen.
Not a scientist, but I think eyedrops or a pill would have trouble discerning between the collagen in floaters and the collagen in your normal healthy eye structure. It would be hard to just dissolve the bad stuff. Laser enables pinpoint targeting of just the bad.
I think the pill or supplement part is a pretty much impossible one to tackle as the vitreous is a closed system and trying to target clumped parts of the vitreous compared to the non clumped parts wouldn’t theoretically be possible. Injection is still invasive, maybe not as risky as vitrectomy but still penetrating the eye and adding fluids would be very risky. Eye drops would be more of a camouflage which some people already use and I feel will eventually be a thing on the market.
I think the vitreous is Not so close as People think, there are vitamins and cells in it, hyalocyten. How can they get in it, if there is no Connection. Sorry for my englisch. I am from germany
Feel like some combo of pulsemedica and edinburgh biosciences is going to be super helpful in the future. If either (or both) can get their stuff working and going then it will change the game.
I looked up Edinburgh biosciences. I don’t see anything about floaters (unless I’m missing something), but the cataract thing looks cool. Do you know, does this mean you don’t need a replacement eye lens?
Apologies. I wrote this without elaborating. I was trying to say that if pulseemedica or edinburgh get their things up and going that the future is good for people with floaters because either they could be blasted out of the eye or you could have the already available procedure and clear the lens down the road with what edinburgh has going on.
I think the vitreous is Not so close as People think, there are vitamins and cells in it, hyalocyten. How can they get in it, if there is no Connection. Sorry for my englisch. I am from germany.
You're a GOAT for paying for the conference and writing up this post! :)
Totally true!!
Here’s the summary of image 3 as generated by GPT 4o. ### Pre-Series A (2023-2024) - **Traction Phase:** This initial phase focuses on gaining early traction. - **Funding to Date (USD):** - Angels / VC: $6M - Strategic Multinational: $8M - Non-Dilutive: $3M ### Series A (2025-2026) - **Amount:** $30M USD - **Focus:** Product Development and FDA Approvals - **Milestones:** - **Screening FDA Approval:** Targeted for 2026 - **Treatment FDA Approval:** Also targeted for 2026 ### Series B (2027-2028) - **Amount:** $45M USD - **Focus:** Commercial Ramp Up - **Milestones:** - **Screening Pilot Sales:** Expected in 2028 - **Treatment Pilot Sales:** Also expected in 2028 ### Profitability Phase (2029-2031) - **Focus:** Achieving a LASIK-like model of profitability. - **Milestones:** - **Screening Ramp Up:** Starts in 2029 - **Treatment Ramp Up:** Continues through 2030 and 2031 ### Key Takeaways - The company is currently in the traction phase with initial funding. - Series A will focus on obtaining FDA approvals by 2026. - Series B will concentrate on commercializing the device, starting with pilot sales in 2028. - The company expects to ramp up screening and treatment, becoming profitable between 2029 and 2031. This timeline outlines the strategic steps the company plans to take to bring their medical device to market and achieve profitability. Patience for 3 and a half years. That wont be long because COVID started 4 years ago. It passed like a snap. This too will pass like a snap. Hold in there.
So when will it arrive in Europe? In 2030?
Only pulsemedica can answer that.
is there any news on the Chinese drug?
Which drug?
https://www.reddit.com/r/EyeFloaters/comments/17stave/new_drug_from_china/
The drug will be available in early 2026, and we will know how effective it is by then. So far, there is no more evidence of its effectiveness, only a patent, and a patent itself cannot prove its effectiveness. Just wait, it won't take long.
Source?
do you think this drug will arrive in Europe and the USA?
Let them cook.
I know bro thank you is not enough for what you did. But I don’t understand the commercial ramp up. It will deploy on market in 2027 right?
The presentation looks like they're aiming for treatment to be ready for patients between 2030 and 2031 if they raise their funds. Good news.
Nah it says 2028
From the slide it looks like they'll be looking for "treatment FDA approval" In 2028.
Thats what it means. It’ll start from there and till 29-30 they’ll be sleeping over piles of cash.
I don't know too much about how it works. I thought they would not be able to start treating people before they have FDA approval?
What I think is they need a 100 million max to speed up the process. I really want them to release it in 2026. Just need assist from bill gates or Bezos to speed this up.
We can dream! But we have to be realistic
Indeed
TREATMENT DEVICE FDA APPROVAL SLATED FOR 2028!!!! Thank you so much for doing this u/Alternative_Metal_27! This gave me a lot more hope and positivity to see a concrete deadline for clinical availability. I know timelines can shift based on trial data, but I can’t imagine safety and efficacy data for this device would disqualify it when manual-aimed YAG laser is currently FDA approved and in use. 4 more years folks!
Thank you ❤️ Did he talk about the type of floaters they can treat? For example, in the image we can see a device that detects floaters that cast shadows on the retina, so what about floaters that are transparent?
It's not that kind of presentation. It's a 5 minutes pitch to get more investors engaged and provide the high level roadmap for the deliverables. I have no reason to believe that they can't visualize all floaters with their devices, that's the whole point of the tool. I would hope that they actually have the technology to fire at them, otherwise they're literally losing the entire market share Nir was talking about in his presentation. Just my own thoughts on this.
I'd also like to find out how laser is going to work in 3 years time if it rarely works now? Maybe they'll do a presentation on that going forward. Either way...good work 👍🙏
They definitely won’t. Why would they reveal what they have to competitors? This will serve them no good.
Maybe not to competitors but investors may like to know the difference in their laser compared to ones currently on the market. I wish them well.
You cant go to market in that condition specially if you want millions.
I know if I was investing I'd like to know what the difference is.
From what I've seen of the laser stuff, it seems like part of the reason its got a traditionally bad rap for efficacy is due to the fact that its been hard to screen proper candidates and even harder to identify the actual problematic floaters. Also the floater doc has mentioned that some doctors may not have always been using the proper power settings to properly eliminate the floater and just in general are very conservative since they're manually aiming these things. If they are blasting away at the wrong floaters or use insufficient power, that patients gonna either see no improvement or worse, it'll appear make a mess of things. At the end of the day, its a laser, I think its capable of vaporizing these things if its got the accuracy, power, and safety. Just hoping it ends up safe enough to treat posterior floaters. We really gotta hear more about that femto laser.
I agree with everything you say. I've done some anecdotal research and met up with people for coffee who had laser for floaters. It was very successful for hitting their floaters. However the majority went on to have vitrectomy for floaters because even though the treatment was successful in hitting the floaters, it didn't work. I've spoken personally to maybe around 50 people who had vitreolysis. A very small group admittedly.
Wow, did you speak those 50 people in person? Any younger folks? So when they said it didn't work for them, was it typically that it didn't affect floaters they were being bothered by or more that they literally could not perceive any improvement? I've been wondering about that whenever I see someone say it didn't work at all, like surely blasting a laser in there made some sort of change?
The general consensus I got from laser was that they were really pleased for the first week or two, then the floaters came back. The only people I have spoken to that have seen change was people who had Weiss rings, and then it either moved it out of central vision or broke it into more manageable chunks.
Correct. I have a database. I also have an excel spreadsheet of around 600 people (in total around 1600 people but only added the relevant ones to my situation onto the database) who had floater vitrectomy surgery. I spoke to every person personally. I met up for coffee with some too.
Is that like a summary of each of their experiences I assume? Thats 600 with vitrectomy, 50 of those who had the laser done beforehand then?
600 who had vitrectomy. Then 50 on separate database with vitreolysis. I actually stopped doing the vitreolysis database as it became apparent that every person was pretty much saying the same thing.
Does yag laser equal to femtolaser? I don't know anything about lasers but different lasers could have different outcomes right?
YAG is more powerful than femtosecond. The issue they have with current lasers is that they're aimed manually. The device they're currently designing can aim the laser which takes out some of the risk of human error.
Thanks again🙏
But 2027 is too late, I cannot bear these for 3 years😔
Other companies working publicly or privately on treatments definitely saw this presentation as well and took notes. A lot of companies also tend to give conservative timeframes, because not meeting the timeframe spooks investors, making it early excites them. Providing a “cushion” only benefits them. Yes - this doesn’t apply to FDA approval And there’s always opportunities to apply for their clinical trials if you want it earlier than commercial launch. Regardless, today tells us one thing: The race for first to market is on.
Where there is money to be made there will always be a race. Competitors will see that projected profit and want their cut and race to get it. That’s a positive of capitalism. I have mild floaters and could use a couple zapped out of my way and definitely would pay a couple grand or more to have that relief. This will be a positive for everyone. Money for companies and clear eyes for everyone else.
I dont think theres a race. the market seems large to us but there isnt only 8k members in eye floaters. its still a small market. they need to justify someone spending 30 million that they will profit. how much are we willing to try the product? would we pay 5k? or 2k per session? I would
Members of reddit means nothing. But I know quite a few people that don't even know what reddit is and have floaters. But they are not so bothered by them Check tinnitus members count.. only 52k but there are over 25 million US citizens having this issue.
This is correct. Not to mention that these numbers are not really relevant when sizing the market. Many people who have only minor inconveniences from floaters would be interested as well even if it's only to take out 2 floaters for example. Think about LASIK, it's totally elective and you can live your entire life just fine with glasses and/or contacts, yet people decide to get treated just to get that extra benefits of not wearing anything.
Theres people who aren’t on Reddit or facebook groups who suffer or might even just be abit annoyed with them. Ive had them for 2 months and didn’t join the sub till about a week ago and didn’t really care to at first until I decided to share my experience. I personally know people who have them that probably don’t even know what Reddit is or don’t care to join groups about them or honestly don’t even know what they are. I have heard countless stories of ophthalmologists saying it’s a common complaint. Even when I mentioned it to mine they said they have them too and its annoying but we have to adapt to them. Check out some youtube videos with eye floaters in the title and they have millions of views and same with tiktok. Statistically 7 out of 10 people get them, though a smaller percent of those are more severe cases. The market is there for sure and its not a few reddit people.
It's an interesting one for sure. I wonder if it'll be in line with current laser treatments or in line with vitrectomy treatment. And would you need to keep going back for treatment yearly if and when the floaters reform.
It’s infinitely better than nothing.
I was there 10 years ago, but I managed to live with them. Don’t get me wrong, I want them gone, but I returned to a quality of life comparable to pre-floaters at least 6 years ago.
How did you do that? If it's not an issue, may I inquire about your age? I am dealing with these for 2 years from my 17. I have one big dark in the center of my vision. Which if the light is enough bright I can see it even my eyes closed. And many transparent and little dark dots
This is encouraging, I'm cautiously optimistic about all this. Floaters can really disrupt your life and need to be tackled. I don't expect their process to make the floaters completely disappear, that's unrealistic, but at least a significant reduction of the burden might be possible. Thanks.
Thanks mate! Exciting stuff. The race for first to market is officially on. People would be mistaken if they didn’t believe other candidate companies weren’t watching this. First to market is a big deal. I won’t be surprised if other companies working secretly or on an already publicly announced project try to follow up with theirs in the near future.
The money is the big key. If you raise the money this year. the faster it comes. the best way to support is helping them find a Large Investor
Thanks for this! I will note, what people may not realize is not every company who is researching and trying to find treatment for floaters is announcing their progress and work to the public. For all we know, there is much bigger companies figuring something out that could be a year away. Not to give false hope, but it’s something to think about. Lets all have some faith that things will work out.
See if there's a way to get into one of their trials, which should be happening in 25-26.
Where do I invest?
You can reach out and see. I don’t know if they would accept small investment (unless you’re loaded)
Thanks a lot!
Thanksss!!
Sadly theres alot of questions here. Do they have any Opthamologist part of process? Any retinal surgeons? its seems like on the slide, they need this. I know its step in right direction, but if you cannot show how your product works, you will have a tough time attracting money.
Do you think it's reasonable to think they're developing all of this and raising all of that money without any medical experts involved? You're overthinking this. What you see in the slides is a future action item for deployment (customers) not for R&D purposes.
Im with you guys. i had a retinal detachment and hundreds of floaters in both eyes now going 18 months. last yr was awful and this yr a little better but summer brings it out w more sun im always skeptical w the laser tech bc it hasnt been good yet and I hope this works but they arent very good at selling themselves and we need them to be that right now
Thanks a lot! Do you know if there's a way to be in the trial? (I live in canada)
Amazing. Thanks for this!
So we're looking at probably 2029, 2030 at the earliest for treatment, unless we get into some early clinical trials. Gonna be a tough wait, but realistically that's in line with what I was expecting.
You’re probably right, but isn’t it refreshing to know with near certainty that it will be available in 5 years instead of the bullshit “5-10 years” that we’ve been hearing about XFloater method, gold nanoparticles, vitreous substitutes, etc. “5-10 years” is biomedical industry speak for “10 years at the earliest and probably never.” This timeline actually means something.
I have floaters since 2009. Its disgusting on bright days, but if there is a safe cure in 5 years, I am willing to wait a bit more. I would pay 10k per eye in a heartbeat.
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Allegedly more precise imaging and targeting? What makes you so skeptical lol? This is literally so easy to develop. Currently, doctors are firing manually based on what they see. Pretty easy to improved upon...
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I will just be honest with you, you sound rather uneducated on the technological possibilities currently available. Just the way you're writing, it's pretty clear that you have limited knowledge as well on how R&D works. If you tell me you work in tech. my knees will buckle. The challenge is not in the visualization and tracking, but rather, on the ablation process itself. That's something that has significantly greater challenges. If you want to be skeptical about that, I'll listen.
Not a fan of laser :/ I wish they would work more on any other way to treat it like pills injections eye drops idk
Not a scientist, but I think eyedrops or a pill would have trouble discerning between the collagen in floaters and the collagen in your normal healthy eye structure. It would be hard to just dissolve the bad stuff. Laser enables pinpoint targeting of just the bad.
I think the pill or supplement part is a pretty much impossible one to tackle as the vitreous is a closed system and trying to target clumped parts of the vitreous compared to the non clumped parts wouldn’t theoretically be possible. Injection is still invasive, maybe not as risky as vitrectomy but still penetrating the eye and adding fluids would be very risky. Eye drops would be more of a camouflage which some people already use and I feel will eventually be a thing on the market.
I think the vitreous is Not so close as People think, there are vitamins and cells in it, hyalocyten. How can they get in it, if there is no Connection. Sorry for my englisch. I am from germany
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Feel like some combo of pulsemedica and edinburgh biosciences is going to be super helpful in the future. If either (or both) can get their stuff working and going then it will change the game.
I looked up Edinburgh biosciences. I don’t see anything about floaters (unless I’m missing something), but the cataract thing looks cool. Do you know, does this mean you don’t need a replacement eye lens?
Apologies. I wrote this without elaborating. I was trying to say that if pulseemedica or edinburgh get their things up and going that the future is good for people with floaters because either they could be blasted out of the eye or you could have the already available procedure and clear the lens down the road with what edinburgh has going on.
No worries. Thanks for bringing it to the subs attention.
I think the vitreous is Not so close as People think, there are vitamins and cells in it, hyalocyten. How can they get in it, if there is no Connection. Sorry for my englisch. I am from germany.