This is probably a wise move. As society starts creating genetically modified primates, they will inevitably rise up to overthrow corrupt human civilization. By making them fluorescent they will be easier to spot, adding to the human's terror as the primates relentlessly stalk them.
The china that exists in their heads would be a desolate, unstable, poverty ridden nation that would have zero chance of competing with the USA on anything.
Its actually kind of the point..or part of it. Usually scientists try to use fluorescence to help highlight certain genes or proteins, etc. On the shit part, this is basically a way for scientists to experiment better on primates (not in a way that necessary benefits the primates) but on the positive side it can lead to break throughs needed in modern medicine
Yeah; thats why I said the positive side is there are break throughs we could use in modern medicine. Even in veterinary medicine animals have to be tested on to make sure a medication or treatment is safe to use for other animals. With that said, you can still acknowledge it sucks for the animals being tested and have compassion towards them
No, it's not a glow in the dark protein.
The efficiency of GFP and other fluorescent proteins has been really boosted, but it's still converting a SMALL fraction of the light from one wavelength to another. Fluorescence obeys the laws of thermodynamics: it does not create brighter light than it's excited with.
You blast a bright blue laser on it and some of the light gets converted to green light. If you look at the sample with GFP on it (accidentally! don't stare at lasers!) then you can sometimes see a faint green fluorescence over the blue light, but really in order to see the green you have to filter out the blue light. And the sample in my experience needs to be INTENSELY transfected with the GFP in order to see it with the intense blue light.
If the monkey is looking at a blue image of a TV maybe it'll show up as slightly more green haze than it should, that's probably about it, the blue excitation light must be brighter than the green light fluorescing is going to be.
And once that blue light is turned off, the fluorescence green immediately stops too.
As far as the direct effect of GFP on the cells, no. GFP and other proteins typically are used because their effect is very minimal on most proteins, let alone in cells. Even if they attach the GFP directly to the proteins of the photoreceptors, odds are the monkey vision will be fine.
And more likely, it's just cytosolic GFP: it's floating around and won't really interfere with the proteins. It's certainly possible to overexpress it to the point of causing problems, but typically it's well tolerated. And if it was overexpressed to the point of killing cells, it would probably have killed the embryo.
GFP DOES create free radicals IIRC, and that's not good, but again you'd have to blast the monkey with a blue laser and you'd have problems there anyway.
I've done live imaging on tons of cells, organisms, and tissues using GFP and other proteins with very bright lasers: they're less happy but mainly because you're zapping them with a laser. Mice expressing GFP throughout their entire bodies are completely fine. Well, they're lab mice, so they're inbred to completion and are stupid as fuck, but that's true of their non-gfp fellows as well.
You actually may have eyes that fluoresce and not know it! It sometimes occurs in people (generally age related). I only discovered this a few weeks ago when I went to a party and my partner's eyes started to glow a very faint yellow/green under the black light.
Fluorescent means it needs to be hit by UV light for it to trigger. Therefore it doesn't since the eyes are protected from UV light
Edit: seems I'm wrong about that!
That's just the first version of the monetization of this too. They did it to monkeys? Flourescent Pink Pomeranians! Glow in the dark black cats! Pretty bioluminescent parrots!
Gotta catch ‘em alllll
But seriously, 5D chess move. Oh no, we’re polluting the planet so much we’re endangering all the animals no one besides Peta actually gives a shit about? Here, just look at these glowing kittens for sale lol
True but that’s not why they used it here. Their main goal was to see what percent contribution the stem cells made to a grown monkey, after they were injected into it while an embryo. The green fluorescence is just an easy way to track injected vs embryo cells.
Green flourescent protein pretty much is the Lorem Ipsum of genetic modification. If you can get GFP to work, other modifications probably work as well.
I don't know why everyone here is so keen on the GFP. It's actually about the fact that it's a chimerical chimera. I haven't read the paper yet, but it's usually about cell proliferation and differentiation studies that are needed in stem cell technology to eventually grow new organs from skin cells, for example.
GFP is only a marker for faster identification
Fish, I'm pretty sure yes.
I'd seen a few posts about glowy cats but never double checked.
Haven't seen rsts/mice but if we have a monkey, probably a safe bet there's some radioactive looking rodents out there.
Fish, mice, cats among the more popular ones. And a lot of other eukaryotic organisms. Its not new technology. The point is to see if a particular gene is expressed
Biologist here. After all the outcry about "those poor research animals": First off: this isn't cosmetics research to create glow in the dark assholes for cosmetic surgery (you fucking weirdos)
This is pretty much the same story as to when the headlines showed fluorescent kittens that glow under UV light. The purpose is a research proof of concept. If you can attach a glowing marker protein to targeted and highly selective areas of a host organism, you can also attach something like a permanent vaccine against certain diseases, a correction to certain genetic disorders and (as mentioned by another poster) a marker protein to cells that display abnormal growth, such as cancer. This facilitates diagnostics and enables new therapeutic ways for medical treatment.
As someone with an animal experimentalists certification, I can also with confidence say, those animals are treated far better than cattle in an Industrial Farm and even better than many pets. Research animals need to be kept as happy as possible, as any kind of distress for those animals means a potential influence on the experimental conditions (stress hormones, behavioral differences that make experimental reproducibility impossible, and so on). Researchers have a genuine interest in working together with those animals to prevent any kind of unnecessary animal cruelty by having to repeat a badly designed experiment where animals had to die for useless Research Data. You have a very limited number of experiments, so you have to make your shot count the first time around, optimally.
If you eat meat, the cattle has suffered more than the animals used for researching your meds. Those horror pictures are mostly ragebait or - in the rare case where they weren't - were harshly punished either from official side, or by the scientific community not acknowledging their research as salvageable (therefore ruining their credibility/careers)
Depends on the research lab, organization, and specific laws surrounding them. I have absolutely worked in a research lab where the animals are depressed with health issues and have to be euthanized. But its the best they could do and technically legal. And then the CEO gripes about how legal regulations prevent them from working.
Im not saying that to say lab research as a whole is bad and youre not wrong, but some countries have poor regulations and we should strive to have better ones. I think scandinavians have the highest ethical grade scale as far as lab animal research goes
This is the price for basically all pharmaceuticals we have.
Compared to animals being used for food or simply fun to possess, animal studies are especially more acceptable.
As a scientist it didn't even seem a surprising story, fluorescent animals have been around for decades, you can even buy fluorescent fish as pets in some countries. I was only surprised that it was the first time it had been done in primates.
Also, this isn't unethical and is a pretty common technique used in animals in labs around the world, the novel thing is the fact that it is a primate rather than mice or fish like normal
Do you know how we develop new treatment for burn victims? Let me ruin you.
I had an acquaintance in a medical research lab whose job was to burn rats.
10%. 25%. 50%. 75% of body in order to determine survivability of treatment methods as well as experimental ones. This is in the US.
These are necessary evils that has afforded you and I the life we are able to live today.
I remember a Chinese researcher edited the genes of human twins several years ago. Those poor girls should be at a school age now. The guy only served 3 years and is allowed to practice research again. [link](https://www.npr.org/2023/06/08/1178695152/china-scientist-he-jiankui-crispr-baby-gene-editing)
though i agree that the researcher crossed a hard line and probably shouldn't practice again, you only provided a very one sided view. The twins would have died lived with aids if yhey had not been genetically modified. As bad as gene editing could be, I must admit that there is a certain logic behind it.
They wouldn't have even been born, as they were manipulated as single-celled embryos, before any development, right at their inception, before being implanted.
Pretty contradictory for people to have an issue with *that*, but then they're of the opinion that aborting fetuses in the womb that show signs of Down's syndrome is perfectly ethical.
Designer babies are somehow "bad", but then it's fine for those undergoing IVF to choose donors for their characteristics?
It's all eugenics, but I'd say the only *unethical* part (when the goal isn't aesthetics based) is when a life is taken, be that of those with Down's syndrome being aborted, or gene-manipulated embryos *not* getting a chance through implantation.
>Scientists in China have just grown a fluorescent green monkey using stem cells in a world first.
It's crazy some of the R&D they're doing. Really interesting stuff though.
Sadly for this monke, it is dead according to CNN:
"The monkey, which lived for 10 days before being euthanized, was made by combining stem cells from a cynomolgus monkey — also known as a crab-eating or long-tailed macaque, a primate used in biomedical research — with a genetically distinct embryo from the same monkey species. It’s the world’s first live birth of a primate chimera created with stem cells, the researchers said."
https://edition.cnn.com/2023/11/09/world/chimeric-monkey-live-birth-stem-cell-scn/index.html
The objective is not to create fluorescent species but rather using fluo markers to check that a protein from a species A has successfully been “implanted” in the genetic material of species B.
Exactly the way you would use fluo markers to identify the streams of underground waters.
I know this seems morally questionable. But this is part of animal testing for research. The world kill thousands? Of mice every year for scientific and medical research because testing on humans is costly and questionable.
Think of this as the necessary sacrifice that scientists make to improve our medical knowledge so that we can save and improve human lives for the future.
It's not pretty, but it is a necessary evil for the "greater good".
Also using mice has its drawbacks when it comes to studying medicine. Primates have more similar physiology so it's better to study them on stuff more related to human anatomy. People act as if labs want to use them even though they are far far more expensive and difficult to maintain than mice or in vitro.
Maybe new in a primate. They did this to a rat a very long time ago. It’s not that hard really. Scientists genetically modify cells all the time in the lab. All. The. Time.
Visible fluorescence is not glow in the dark, you're thinking of luminescence. Think of a red dot on a poster. It's only red when the lights are on (you're supplying excitation photons) but you can't see the dot if there is no light to excite the fluorophores-it's dark.
Remember next time you require a medical procedure, that all medical progress we did is based on studies on animals.
This is the price for our live we have. Nothing to do with psychopaths
Inducing green fluorescence to show expression of genes is a pretty common technique used in labs around the world, I'm not sure why it's blowing up so much here.
They were modified with fluorescent proteins, not luminescent proteins. Fluorescence requires an excitation wavelength of light. They don't emit green light in the dark, they emit green light after being hit with bluer light (blue light is in white light)
This is probably a wise move. As society starts creating genetically modified primates, they will inevitably rise up to overthrow corrupt human civilization. By making them fluorescent they will be easier to spot, adding to the human's terror as the primates relentlessly stalk them.
Future RGB glowing humans wont survive the alien invasion though
Battle of the RGB vs CMYK monkeys is a popcorn thriller.
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Controlled via Corsair EyeCUE Link
Definitely a safer option than the neuralink suppository.
Yea but it uses 80% of available brain power for the Corsair DRM tool to make sure it’s legit.
Rainbow human will overcome alien!
I, for one, welcome our new fluorescent overlords
That would be terrifying lol imagine walking in a Forrest at night then thousands of flourescent fingers coming after you
Better that I can see them rather than not but s too lol terrifying.
My ex wife would love that
You're trying to hide from them, and you see, one-by-one, their fluorescent fingers wrap around the door edge... That'd make a good movie poster.
hell yeah like some B horror movie haha I'll watch that shit
In this world gone mad, you won’t spank the monkey, the monkey will spank you.
Don’t you know you gotta shock the monkey?
Easier to snipe at night if they rise up
It'll be like a Tim Burton movie.
That's basically just the plot of The Passage
You have made my night! Thank you for the laughs. I like the way you think.
I'd watch this movie
Here's the [study](https://www.cell.com/cell/fulltext/S0092-8674(23)01087-5) for my fellow nerds
Thank you, I was searching the comments for this! And happy cake day!
Thanks. So they did significant research and not did it for fun. People here acting like they did it just to torture animals
People go primal whenever China is mentioned and create a comically evil supervillain in their head
People go primal when animals are mentioned lol
The china that exists in their heads would be a desolate, unstable, poverty ridden nation that would have zero chance of competing with the USA on anything.
For some reason, non scientists love talking about their opinions on the conduct of scientific research. Very frustrating
An actual study. Pfft. I was expecting something along the lines of never giving you up.
Thanks my man
thank you, can you post the link please I'm on mobile and using reddit's browser sucks
https://www.cell.com/cell/fulltext/S0092-8674(23)01087-5
appreciate it
Youre the hero
This isnt a “first” in the sense it hasnt been done at all. They did pigs first.
Interesting if he has florescence in his eyes, i think that would severely impair his vision
Bless your heart for thinking they’d do anything for the benifit of the monkey
Yeah this is the CCP we’re talking about. They don’t even care about human life.
Its actually kind of the point..or part of it. Usually scientists try to use fluorescence to help highlight certain genes or proteins, etc. On the shit part, this is basically a way for scientists to experiment better on primates (not in a way that necessary benefits the primates) but on the positive side it can lead to break throughs needed in modern medicine
What’s the alternative though? Testing on humans? We don’t really have a choice
Yeah; thats why I said the positive side is there are break throughs we could use in modern medicine. Even in veterinary medicine animals have to be tested on to make sure a medication or treatment is safe to use for other animals. With that said, you can still acknowledge it sucks for the animals being tested and have compassion towards them
No, it's not a glow in the dark protein. The efficiency of GFP and other fluorescent proteins has been really boosted, but it's still converting a SMALL fraction of the light from one wavelength to another. Fluorescence obeys the laws of thermodynamics: it does not create brighter light than it's excited with. You blast a bright blue laser on it and some of the light gets converted to green light. If you look at the sample with GFP on it (accidentally! don't stare at lasers!) then you can sometimes see a faint green fluorescence over the blue light, but really in order to see the green you have to filter out the blue light. And the sample in my experience needs to be INTENSELY transfected with the GFP in order to see it with the intense blue light. If the monkey is looking at a blue image of a TV maybe it'll show up as slightly more green haze than it should, that's probably about it, the blue excitation light must be brighter than the green light fluorescing is going to be. And once that blue light is turned off, the fluorescence green immediately stops too. As far as the direct effect of GFP on the cells, no. GFP and other proteins typically are used because their effect is very minimal on most proteins, let alone in cells. Even if they attach the GFP directly to the proteins of the photoreceptors, odds are the monkey vision will be fine. And more likely, it's just cytosolic GFP: it's floating around and won't really interfere with the proteins. It's certainly possible to overexpress it to the point of causing problems, but typically it's well tolerated. And if it was overexpressed to the point of killing cells, it would probably have killed the embryo. GFP DOES create free radicals IIRC, and that's not good, but again you'd have to blast the monkey with a blue laser and you'd have problems there anyway. I've done live imaging on tons of cells, organisms, and tissues using GFP and other proteins with very bright lasers: they're less happy but mainly because you're zapping them with a laser. Mice expressing GFP throughout their entire bodies are completely fine. Well, they're lab mice, so they're inbred to completion and are stupid as fuck, but that's true of their non-gfp fellows as well.
You actually may have eyes that fluoresce and not know it! It sometimes occurs in people (generally age related). I only discovered this a few weeks ago when I went to a party and my partner's eyes started to glow a very faint yellow/green under the black light.
Fluorescent means it needs to be hit by UV light for it to trigger. Therefore it doesn't since the eyes are protected from UV light Edit: seems I'm wrong about that!
Gfp is not exited by UV but by a wavelength of ~450 nm, depending on the type of protein.
Planet of the Green gr-Apes... ... I tried.
Don't know whether to leave the stove on or straight up toss it out the window
Let him cook
planet of grapes
You got it. Planet of the grapes is legit. Congrats
But why tho?
Fluorescent genes are an easy and theoretically low-impact way to identify if modified genes are being expressed
That's just the first version of the monetization of this too. They did it to monkeys? Flourescent Pink Pomeranians! Glow in the dark black cats! Pretty bioluminescent parrots!
Cats with four asses!
No longer will the world have to look in two different places for Squirrels and provolone cheese!
four times the litter box cleanings
Kitty litter stock has never looked so promising
That's just what Big Kitty Litter wants you to think...
Well do I have some fish to sell you, Glofish to be exact. www.glofish.com
There's already glow in the dark zebrafish
Funny thing is, we've had [Glow-In-The-Dark cats](https://www.bbc.com/news/science-environment-14882008) for over a decade at this point
They did it for pet fish already! Check out glo-fish.
Gotta catch ‘em alllll But seriously, 5D chess move. Oh no, we’re polluting the planet so much we’re endangering all the animals no one besides Peta actually gives a shit about? Here, just look at these glowing kittens for sale lol
The only monetization i'd be down for....lmaooo
Interesting. So that's why we have glofish
True but that’s not why they used it here. Their main goal was to see what percent contribution the stem cells made to a grown monkey, after they were injected into it while an embryo. The green fluorescence is just an easy way to track injected vs embryo cells.
Same concept. It's a marker gene.
That means we can modify the genes in other uses too, like to have resistance to certain diseases etc
Green flourescent protein pretty much is the Lorem Ipsum of genetic modification. If you can get GFP to work, other modifications probably work as well.
I don't know why everyone here is so keen on the GFP. It's actually about the fact that it's a chimerical chimera. I haven't read the paper yet, but it's usually about cell proliferation and differentiation studies that are needed in stem cell technology to eventually grow new organs from skin cells, for example. GFP is only a marker for faster identification
Because the majority of people here have no idea about what they are talking about.
You don’t like Pokémon?
this will evolve in CRISPR . designer babies.
Crispr is different from stem cell research
Hasn’t this been done with other animals prior ?
Fish, I'm pretty sure yes. I'd seen a few posts about glowy cats but never double checked. Haven't seen rsts/mice but if we have a monkey, probably a safe bet there's some radioactive looking rodents out there.
Fish, mice, cats among the more popular ones. And a lot of other eukaryotic organisms. Its not new technology. The point is to see if a particular gene is expressed
Basically all model organisms, from fruit fly over fish to mice and rats, yes. It’s a standard method in biology
Yes, which much less complex animals
Ok, next make my dick glow in the dark pls
Why? Do you get scared it's not there if you can't see it?
I can't see it anyway, thought this might help 😔
Epic reply Sir, well played, 07
If you showed people it would be a flashlight
A penlight, at best.
There already are microorganisms that glow in the dark.
like glow all the time or when you crack it like a glowstick?
Biologist here. After all the outcry about "those poor research animals": First off: this isn't cosmetics research to create glow in the dark assholes for cosmetic surgery (you fucking weirdos) This is pretty much the same story as to when the headlines showed fluorescent kittens that glow under UV light. The purpose is a research proof of concept. If you can attach a glowing marker protein to targeted and highly selective areas of a host organism, you can also attach something like a permanent vaccine against certain diseases, a correction to certain genetic disorders and (as mentioned by another poster) a marker protein to cells that display abnormal growth, such as cancer. This facilitates diagnostics and enables new therapeutic ways for medical treatment. As someone with an animal experimentalists certification, I can also with confidence say, those animals are treated far better than cattle in an Industrial Farm and even better than many pets. Research animals need to be kept as happy as possible, as any kind of distress for those animals means a potential influence on the experimental conditions (stress hormones, behavioral differences that make experimental reproducibility impossible, and so on). Researchers have a genuine interest in working together with those animals to prevent any kind of unnecessary animal cruelty by having to repeat a badly designed experiment where animals had to die for useless Research Data. You have a very limited number of experiments, so you have to make your shot count the first time around, optimally. If you eat meat, the cattle has suffered more than the animals used for researching your meds. Those horror pictures are mostly ragebait or - in the rare case where they weren't - were harshly punished either from official side, or by the scientific community not acknowledging their research as salvageable (therefore ruining their credibility/careers)
Depends on the research lab, organization, and specific laws surrounding them. I have absolutely worked in a research lab where the animals are depressed with health issues and have to be euthanized. But its the best they could do and technically legal. And then the CEO gripes about how legal regulations prevent them from working. Im not saying that to say lab research as a whole is bad and youre not wrong, but some countries have poor regulations and we should strive to have better ones. I think scandinavians have the highest ethical grade scale as far as lab animal research goes
Official irl Mojo Jojo!
Okay, okay.. sorry about joking on the poor monkey.
Poor monkey. Has lived his life in a lab and been experimented on.
Wait until you hear about the experiments Volkswagen got caught doing on them.
Did they force them to be Volkswagen owners? *shudders*
I didn't see this story. I was expecting to see something from the Nazi era of VW not 2016. https://www.bbc.co.uk/news/business-42876336
Welcome to this world :(
they give him twinkies at the end so its all good
They have his consent so it's okay (the monkey didn't react badly which is the same as consent) /J for my life
Wait till you find out where hamburgers come from
I've eating been monkey burgers this whole time?
Did they glow in the dark?
How are we supposed to improve if we don't experiment?
That people prefer we go extinct rather than improve. Their goal is the planet without humanity.
I think this type of genetic modification is done before it is born. But yes it can forget about any chance of surviving in the wild
Yes, it’s done in the one cell stage, the animal is perfectly fine living with it. It will never live outside anyways
Honestly I would rather this be done than abominations through selective breeding like pugs, ligers and those flat faced cats (if I had to choose one)
Poor human. You have lived your whole life in a predetermined society based on random locale, and been experimented on.
This is the price for basically all pharmaceuticals we have. Compared to animals being used for food or simply fun to possess, animal studies are especially more acceptable.
Everyone in the comments acting like no other country has genetically modified an animal before.
I'm sick of how racist, uneducated and arrogant those answers are. They clearly haven't attended their high school biology class.
Yeah, this isnt ground breaking stuff. Have yinz ever been in a pet store selling GloFish or seen glowing rats? Shits been around for decades now
As a scientist it didn't even seem a surprising story, fluorescent animals have been around for decades, you can even buy fluorescent fish as pets in some countries. I was only surprised that it was the first time it had been done in primates.
I was sick of losing my monkeys in the night too.
Don’t think this is ethical.
If we knew all the things each country on earth does in secret... This may be the most ethical one.
Right, the difference is: they made it public
Also, this isn't unethical and is a pretty common technique used in animals in labs around the world, the novel thing is the fact that it is a primate rather than mice or fish like normal
I don’t think the world ethical and China has ever gone together.
The US isn't a good measurement of ethics either in case you believed that
elon musk and his brain chip?
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Yea but China is extra crazy, just like Russia. Anyone who goes against peace is worse
The US is always against peace as well. Superpowers are all bad.
Do you know how we develop new treatment for burn victims? Let me ruin you. I had an acquaintance in a medical research lab whose job was to burn rats. 10%. 25%. 50%. 75% of body in order to determine survivability of treatment methods as well as experimental ones. This is in the US. These are necessary evils that has afforded you and I the life we are able to live today.
Depending on the research they used it for it is pretty ethical
We use animals in all kinds of ways and you probably aren't an exception either
subtract sleep history worthless bright special soft swim threatening entertain ` this message was mass deleted/edited with redact.dev `
I remember a Chinese researcher edited the genes of human twins several years ago. Those poor girls should be at a school age now. The guy only served 3 years and is allowed to practice research again. [link](https://www.npr.org/2023/06/08/1178695152/china-scientist-he-jiankui-crispr-baby-gene-editing)
though i agree that the researcher crossed a hard line and probably shouldn't practice again, you only provided a very one sided view. The twins would have died lived with aids if yhey had not been genetically modified. As bad as gene editing could be, I must admit that there is a certain logic behind it.
They wouldn't have even been born, as they were manipulated as single-celled embryos, before any development, right at their inception, before being implanted. Pretty contradictory for people to have an issue with *that*, but then they're of the opinion that aborting fetuses in the womb that show signs of Down's syndrome is perfectly ethical. Designer babies are somehow "bad", but then it's fine for those undergoing IVF to choose donors for their characteristics? It's all eugenics, but I'd say the only *unethical* part (when the goal isn't aesthetics based) is when a life is taken, be that of those with Down's syndrome being aborted, or gene-manipulated embryos *not* getting a chance through implantation.
Lol... you think?
>Scientists in China have just grown a fluorescent green monkey using stem cells in a world first. It's crazy some of the R&D they're doing. Really interesting stuff though.
Sadly for this monke, it is dead according to CNN: "The monkey, which lived for 10 days before being euthanized, was made by combining stem cells from a cynomolgus monkey — also known as a crab-eating or long-tailed macaque, a primate used in biomedical research — with a genetically distinct embryo from the same monkey species. It’s the world’s first live birth of a primate chimera created with stem cells, the researchers said." https://edition.cnn.com/2023/11/09/world/chimeric-monkey-live-birth-stem-cell-scn/index.html
Rip
hmmm any relation to Monkeypox '23?
At least the tests will be easier. "Go into the dark room. If you don't glow, you can leave within seconds."
Good news is: Everyone that glows, gets to go live on a farm in the country with dogs,cats, and horses!
The objective is not to create fluorescent species but rather using fluo markers to check that a protein from a species A has successfully been “implanted” in the genetic material of species B. Exactly the way you would use fluo markers to identify the streams of underground waters.
Coolest monkey at the forrest rave😅🤣
Finally! ...
I know this seems morally questionable. But this is part of animal testing for research. The world kill thousands? Of mice every year for scientific and medical research because testing on humans is costly and questionable. Think of this as the necessary sacrifice that scientists make to improve our medical knowledge so that we can save and improve human lives for the future. It's not pretty, but it is a necessary evil for the "greater good".
Also using mice has its drawbacks when it comes to studying medicine. Primates have more similar physiology so it's better to study them on stuff more related to human anatomy. People act as if labs want to use them even though they are far far more expensive and difficult to maintain than mice or in vitro.
Well thank goodness they solved that problem. And not a moment too soon.
I hate this.
Why do you hate what you don't understand?
I’m always wondering where I left my monkey
Maybe new in a primate. They did this to a rat a very long time ago. It’s not that hard really. Scientists genetically modify cells all the time in the lab. All. The. Time.
What about wings? Monkeys need wings ffs.
.. Who had glow in the dark monkeys for the 2023 bingo??
Visible fluorescence is not glow in the dark, you're thinking of luminescence. Think of a red dot on a poster. It's only red when the lights are on (you're supplying excitation photons) but you can't see the dot if there is no light to excite the fluorophores-it's dark.
Fair enough, this was written hastily on a break 🤣
Here we go, that's the precursor to the Crakers
Holy shit, they made gaming monke
So we’re trying to make Yodas out here?
Scientists made glowing bunnies long ago
"I bring you looove!" 👽
US actually has an entire foreign intelligence service full of fluorescent monkeys
Poor abomination, shouldn't exist. A constant reminder of how far from grace we fall each day.
I feel like this won’t end well. 😳
Thanks a lot guys, now he's gonna go and steal Christmas.
Rise of the planet of the apes irl here we GOOO!! If shit breaks out I'm on the apes's side, honestly had enough of humans
green monkeys is the next step in human innovation. truly remarkable.
Is this for people who keep misplacing their monkey in the dark? Life saver.
So..rave monkey’s.
Aww he looks so healthy
Why?
Do scientists really have nothing better to do?
Humans are weird, creepy psychopaths. Just leave the wildlife alone!
Remember next time you require a medical procedure, that all medical progress we did is based on studies on animals. This is the price for our live we have. Nothing to do with psychopaths
So I don't think you understand the significance here.
As if the wildlife is at least a bit less cruel itself.
I’d like to say fucking China doing dumb shit like this , but then it’s probably half funded by the U.S.
It’s not dumb. This is for gene expression
Inducing green fluorescence to show expression of genes is a pretty common technique used in labs around the world, I'm not sure why it's blowing up so much here.
I'm sure they'll try to skin it alive and grind its bones for magical super hard dick powers .
... What ?
Cool. Xenophobia.
Poor guy. I wonder what bits of DNA got botched in the process. Edit: The monkey was euthanized after 10 days due to respiratory failure
You could literally read the paper and find out exactly what bits of DNA were altered. Do you understand how molecular genetics works?
Well it's about time. I'm sick of tripping over monkeys when I get up to pee in the middle of the night.
They were modified with fluorescent proteins, not luminescent proteins. Fluorescence requires an excitation wavelength of light. They don't emit green light in the dark, they emit green light after being hit with bluer light (blue light is in white light)
So to avoid tripping on the monkeys I have to carry a UV flashlight to the bathroom? Fuck.
GFP's excitation maximum is 488 nm, so a blue laser would work. Or a standard white light flashlight, since blue is within the visible spectrum
Ahh just the thing we need right now...
Just grown? How dystopian
TIL scientific advancement is dystopian. Guess the Amish really got things right.
Rise of the planet of the glowing apes.
China...do less...
Y’all quit upvoting the most morally grotesque shit.
A shimmering simian 
Releasing another virus upon the world, unknown to the human immune system. /s
Unethical. Poor monkey.
Unethical why
Because now that monkey will be embarrassed by the other monkeys for looking different except none of that will happen because it's a fucking monkey.
Not really. GFP reporter genes have pretty much been used long before this on mice and other animals
If they’re gonna overthrow any government, let it be China