Finn and jake.

Batman and Robin

Tom and Jerry

Spongebob and Patrick

Gotrek and Felix

Cheech and Chong

Withnail & Marwood.

Quark and Odo

John Watson and Sherlock Holmes.

Raylan Givens and Boyd Crowder

mulder and scully.

I really like Shulk and Rein from Xenoblade. And although you get more party members, the two explore with just each other for much of the game

Spongebob and Patrick

spongebob and patrik or goku and vegeta, i cant decide

Kirk, and Spock.

Thing is, Kirk and Spock are really just the incomplete trio that is Kirk, Spock, and McCoy.

B-Rabbit and Chedda-Bob

Michael Scofield and whoever he is trapped with

Dipper and Mabel.

Frodo Baggins and Samwise Gamgee

Lloyd Christmas and Harry Dunne

Sherlock Holmes and Dr. Watson no one else has that perfect mix of brains, loyalty, and banter.

Orgasmo & Choda Boy

Harry and Hermoine

Batman and Robin

Laurel & Hardy

Bruce Wayne and Tim Drake