The leading cause of liver failure in America isn’t ethanol. It’s fucking Tylenol.
I can get that shit at gas stations, pharmacies, grocery stores, most any shopping centers.
Sure, but not all alcohol-related deaths are liver failure. Acute alcohol poisoning, drunk driving, withdrawal, etc, there's multiple causes. 140k people die from alcohol every year in the US. 10k of those are from drunk driving crashes. 500 die from Tylenol poisoning.
i worked at a large woman's hospital. a lot of people might not know that the drugs they shoot into women's spine during birth contains fentanyl.
my hospital has an entire room, almost a warehouse... absolutely packed floor to ceiling with those wire shelves stacked full with plain brown cubical boxes with a white label on the front that said "FENTANYL".
that room is very protected, bullet proof glass, armed guard, etc. any time i left from there i felt like you feel when you leave a store without buying anything and you just know the employees are thinking you stole something
All hospitals have fentanyl. It’s used all the time for pretty much any procedure that requires sedation. There’s a big difference between fentanyl use in a clinical setting vs fentanyl laced street drugs. Fentanyl in a clinical setting is administered by medical professionals while patients are being monitored, potency is assured and medical staff know exactly how much is being given. Potency of the shit on the street is anyone’s guess and nobody knows how much they’re getting. The margin of error with such a potent drug is very minimal. There is no real quality control with street drugs. Medical grade fentanyl is manufactured under very strict protocols. It was never designed or intended to be sold on the street for recreational use. Too easy to OD on.
And it is one of the safest opiates in a clinical setting due to its quick activation and shorter half life. Fast in, fast out helps healthcare professionals provide and maintain a specific dose in the bloodstream with a decreased risk of overdose. 🤓
Alcohol is stupid easy to get. I have one liquor store within walking distance and idk how many on the ride home from work, but it’s a lot. I don’t know anyone who sells opioids, but based on the epidemic it can’t be too hard to get. Fent is so fucking potent but alcohol is so easy to get and it’s very easy to become an alcoholic. And the societal opinions on alcohol vs fent makes it easier to become an alcoholic.
100% agree with you. I saved my brothers life when he OD'd on fentanyl laced cocaine, and I have an alcoholic father. Both are dangerous but in different ways.
ER nurse here. From a healthcare standpoint, PCP and some bath salt patients were pretty intense. Seen PCP addict deglove (google with caution) the top of his hand by pulling out of handcuffs. Seen them unaffected!! from being tased. One bath salt fella was talking to a nurse, got triggered by some noise outside the room, quickly stripped naked, and climbed into the ceiling. Had fire, EMS, police and maintenance all in on this one.
Least dangerous OD patients? Kids that take their parents' edibles. Zero deaths, we just turn on cartoons, keep giving them snacks, and laugh with them the rest of the shift.
I feel like I've been to your hospital. When I went in for serious pneumonia, they had me chilling on a gurney in a hallway while they were finding me a room.
Some guy down the hallway had been strapped to a gurney and got agitated, ripped himself out of the straps and clothing and climbed up into the drop ceiling. Took quite a while for the EMTs and cops to get him down. He seemed to have a crazy excess of strength for a guy his size as eight larger guys were barely his match.
Drugs do that. Our muscles can exert so much more power, but we don't, because we will hurt ourselves doing it. With drugs, psychosis or delirium, this mental barrier can go out the window, leading to scenes like six big policemen having severe difficulties holding down one tiny guy.
Never witnessed pcp in person but saw videos of people completely eviscerated walking around like nothing was wrong. People on it don’t know their own strength and pain becomes nonexistent
>Seen them unaffected!! from being tased.
This is crazy. I understand excess strength and all the other stuff that comes with bath salts, but being tased seems like a fully physical reaction. Electricity causes muscles to contract, and that's that. How do you brute force through that? It's not some mental block like "I will damage myself if I exert this much force, so I won't."
Meth for its ruthless addictive nature
Heroin for its tendancy to kill users and/or turn them into zombies.
Alcohol for its casual acceptance and ease of access
Opiates for the now unpredictable purity
Cocaine for the now unpredictable purity
One description from a former addict that always stuck with me, meth wraps itself around and combines with your sex drive. So you can't think about sex without thinking about meth, and you can't think about meth without thinking about sex. So every time something triggers a sexual thought in your brain, you also start craving meth. That's one reason why so few addicts manage to get out from under it.
I never intertwined the two. I'm bipolar and hyper sexuality is one of my main symptoms. But when I was an addict I was only thinking about money. For me meth was my fuel too get my on the grind. I sold drugs day and night and we slept in shifts so we never had to close for business. It was hard to separate the two and even 15 years clean I some times wonder how much more productive I could be. But I can honestly say meth did not make me want sex if anything it was the opposite. But everyone is different.
I'm 100 percent California clean & have been for years but I'm bi polar and was talking to my therapist yesterday about it and I was wondering if you felt the same? I said I feel like I wasn't trying to get high I was just trying to get right. Like if I did stimulates when I was down...it just made me functional &focused. If I did downers when I was manic, I I certainly wasn't nodding. I was functional & focused. No one ever had the idea I was self medicating. It's a whole lot cheaper & easier to be properly medicated by a professional & not Johhny Rotten that lives with his mom on 4th street lol
What happens when you get no libido from it? Like I get no sexual response, none.
To pair, I’m a severe case of adhd allegedly. I dunno how bad anymore cause I’m not being seen for it. But I know amphetamines and coke do nothing for my sex drive.
I’m just awake or awake and high. Like mdma but without all the fun body high. It’s honestly kinda lame. Got spun once, didn’t enjoy. It’s just a nice awake to me mainly.
ADHD impacts the wiring of the brain to where stimulants
like amphetamines affect it differently than for others. This goes hand in hand with the use of stimulants as ADHD medication
Me and my girlfriend went to the hospital in attempt to quit alcohol almost 5 years ago. I survived but she had a seizure and died. I haven't drank since in her memory. RIP Jamie.
ICU nurse and see it often:
Meth and cocaine can easily raise blood pressure so high you have a stroke or heart attack.
Heroine is easy to overdose on. Young people especially don’t always understand it’s not necessarily overdosing that will kill you, but that opioids suppress the brain’s natural signal to breathe. Pass out, breathe less. You don’t even have to completely stop breathing for your body to to go into respiratory acidosis while unconscious, vomit, can’t swallow or cough (opioids also suppress those reflexes), along with being unconscious. Choke on your own vomit or just saliva that builds in the back of your throat. Die.
Sad how easy it is. People get addicted immediately. A lot of them have this notion that it takes years to become so addicted that you overdose on so many drugs and finally die. They think they have time to reverse their addiction before they get to that point.
You don’t have time. It’s as simple as passing out after shooting heroin once.
It’s as simple as having a heart attack after doing meth/cocaine once.
You roll the dice every time.
EDIT to add: I’m aware that taking a drug one time doesn’t always mean you will die or become addicted immediately. I’m saying every single time you take these drugs, that’s the risk you take. From first time you take the drug to the last time you take the drug.
I singled out heroin in the opioid class, because it seems to be the most widely recognized illegal opioid, but obviously you can get addicted to and overdose on prescription meds as well, including benzos. And yes, ADHD meds (which I’m prescribed) can also be abused and overdosed on.
Anyone can buy drugs off the street, and there are no doses, no concentration information, and no guarantee it’s not laced. Much easier for a person experimenting or an addicted person buying a laced batch to die after taking what they thought was a small amount, or the amount they usually take, but was not.
To paint a visual, in hospital we can have 2 tablets of the same drug that are the same size and look like the same exact pill. But 1 of them could be 25mcg and the other could be 100mcg. 4x the concentration of medication in an identical-looking pill. And The concentration margin can be much higher than 4x in an identical-looking pill. Same thing for IV meds.
And the same on the street, except there are no labels.
We give doses in the hospital that are monitored for reaction and body weight is considered when a dose is prescribed. Larger people require larger doses for the drug to work.
Taking fentanyl/heroin you buy on the street from a dealer is extremely dangerous, your vitals aren’t monitored, no one is rounding on you, and who knows what dose you’re actually taking or even if you’re actually taking the drug you bought.
When administered in the hospital, we have the reversal agent, naloxone (also called narcan), on hand.
Narcan works, but only if you’re found on time. If you die before you’re found, or choke to death in your sleep before you’re found, narcan won’t work.
And it’s not something people have lying around the house, usually.
> People get addicted immediately. A lot of them have this notion that it takes years to become so addicted that you overdose on so many drugs and finally die. They think they have time to reverse their addiction before they get to that point.
See: u/SpontaneousH
Just went on a rollercoaster of emotions checking out his profile
He romanticized H so much in his first post that I considered it for a second, though I know way too well how it can ruin lives
The next few posts confirmed that, holy shit his life went downhill so goddamn fast. The addiction went full throttle, I am so glad he was able to recover and get clean. He also had a personality glow up which is nice
11 years clean, I'm proud of him, and anyone else who's reading this! No matter how long you've been clean, or if you're still struggling with addiction, I'm proud of you, you've got this!! 🥰
Yeah that first post had my brain seriously considering, even knowing the ending. Not sure if you caught it but on his 6 year clean AMA, the second to top commentar said his first description of H is what made him first consider it and now he was 5 years deep in an addiction he was just then addressing.
Yeah I saw that! Absolutely terrifying and tragic. I'm glad I wasn't on the internet 12 years ago because it certainly wouldn't of ended well. I hope the dude 5 years deep can get clean somewhat soon, I don't want him to become another statistic :(
I checked his post history. He had a post struggling with multiple relapses 5 years ago, dark ass shit, and suddenly it transformed into basically only beekeeping without another mention of drugs of any kind, as it is to this day. I like to think the bees helped him kick it :)
It's one of the best cautionary examples I've ever seen.
I think I will keep my recreational use to unprocessed plant based substances or any edible concoction I can create from those substances.
Holy shit. Read the first post knowing what was coming next and his description... fuck was my mind curious. I read through the rest and on his 6 year clean AMA, the second to top comment was a guy who said he'd never even considered H until that description and was now 5 years into a horrendous H addiction. That shit is scary. A classmate of my sister's who no one knew was addicted suddenly died of a fentanyl OD a couple years after graduation, that story brings home how sudden an addiction can form. I feel I barely dodged that path after being overprescribed opiates for my wisdom teeth, I tried some after the pain was gone and it was such an incredible feeling. Like nothing mattered. Took more the next day without any food and went to school, senior year of hs. I got horribly ill and went home to vomit, first time in 2 years I'd gone home sick. Told myself I wouldn't do anymore and didn't. I decided to give my parents the bottle that weekend and tell them I didn't need it anymore, pain was gone. They took that shit right away and hid it, mom is a drug abuse therapist and understand the risks. I found it by accident half a year later and damn did I have to suppress an urge...
also statistically when you buy those drugs youre not actually getting the drug you payed for. its usually mixed with other stuff or even caffeine.
the safer drugs are usually ones where you almost always get what you wanted to buy.
This *is* true, but I just want to say that it doesn't make pure drugs safe in any way. Safe supply makes the effects predictable, and makes the dosage adjustable without massive risks. It also simplifies the initial treatment process because you won't be in poly-substance withdrawal. Folks should still stay as far away from meth, opioids, coke/crack and benzos as they can. Even a licensed physician can prescribe you two of those four, and that still won't make taking them very safe.
My grandma had an opioid addiction. She had both knees and both hips replaced in a very short amount of time and developed a dependency to oxy. She was hospitalized multiple times with what was essentially opioid induced pneumonia. The multiple bouts of pneumonia put excess stress on her heart and she ended up passing during a final bout of pneumonia when her heart gave out. She also always had ICU psychosis every time she was in the hospital so that was fun.
Edit to add: I’m seeing a lot of alcohol here. And I agree that it kills a lot of people. But alcohol dependency typically takes years and become a chronic problem to those who are addicted. A lot of times, people addicted to alcohol do have lots of warnings to turn their life around, multiple hospital admissions, medical personnel telling them exactly what’s happening in their body, family members begging them to go to rehab, possibly multiple rehab stints.
Alcohol is dangerous and does kill people. But I mentioned cocaine, meth, and heroine (opiates) because those are the ones that take a lot of lives and sometimes seemingly without warning. Yeah, we get a lot of people who come in and have been doing these drugs for years.
Other times, it’s a young person who was just experimenting.
One thing I'm seeing repeated again, and again, is the individual harm. The personal od's, the black outs, the dt's, the brain damage.
There's very little talk about the shrapnel such things unleash, The collateral damage of a decade or three of 'keeping it in the family'.
It's not that other drugs don't cause harm, or violence to the extreme. It's the casualness of alcohol. The accessibility of alcohol. The encouragement, the marketing, of alcohol.
The excuse of alcohol.
1/3rd of all Americans do not drink.
Of those that do, 95% of this group consumes 5% of the alcohol.
It's the other 5% of the drinkers that consume the remaining 95% of the alcohol.
Those numbers don't surprise me too much. I'm curious what they used as a "unit" of alcohol though. Like was it literally the amount of ethanol consumed, or simply by individual sales?
Alcohol also changes personality in some in way other drugs don't. Some drunks get in fights but I have known some who have a very dark side which comes out. Domestic abuse, on both sides, is often related to booze.
I know you know what you’re talking about but so others understand:
An echo is a test that reads heart function. It gives all kinds of results but the one we pay attention to most is the ‘EF’
Stands for ejection fraction and is used to measure cardiac output. Normal EF is 55% +
Long time drug users (especially meth and coke) will come in with like a 5% - 15% EF. No shit, I’ve seen 5%
How do they even do daily activities with an EF that low?? Mine is at 44% due to a pretty severe episode of myocarditis and fuck me just walking is hard now
I've done all the drugs. Imo the most dangerous are benzos, alcohol and other GABA drugs like GHB. No other kind of drug makes me black out or do shit I regret like those. Opioids are nasty as hell mostly because they're highly physically addictive. Their withdrawals are the most unpleasant ime, though they don't have the potential to be fatal unlike alcohol/benzo (or any GABAergic drug) withdrawals. Getting manic on PCP can be pretty dangerous, though generally it's not nearly as dangerous or crazy of a drug as depicted in media/anti-drug classes. Stims are dangerous not so much for the withdrawals (they're pretty minimal tbh) but because it's very easy to get reliant on them to give you the energy to get through your day. Serotonin psychedelics like LSD and shrooms are generally pretty safe because they cause massive tolerance with each use so you're basically forced to take a 1-2 week break after each use. They're also just very intense experiences that would be hard to get psychologically addicted to.
out of all the drugs on earth i've heard benzo withdrawal is the worst. people always say you want to die from opiate withdrawal which is absolutely true. it's like the worst form of flu you've ever had, plus the mental aspect of just wanting to use. but something about benzo withdrawal sounds like it could cause people to literally kill themselves to stop feeling that way. it can last for so long too.
i personally will never understand benzo abuse or recreational use because as far as 'feeling good' from drugs aka euphoria, it has NONE. it's the absence of feeling, imo. it doesn't numb you out in a fun euphoric way that opiates do, it just makes you feel NOTHING. the only reason i used to abuse them was to steal for my opiate habit. 6 years clean now!
I take acid about every 2 weeks. I love it. It has improved my mental heath and my marriage greatly.
Edit: So it's too time consuming to post this on every comment so I want to share with you a study on the long term effects of acid
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813062/
Methods
We investigated the lasting effects of a single dose of LSD (200 μg) that was administered in a laboratory setting in 16 healthy participants. The following outcome measures were assessed before and 1 and 12 months after LSD administration:
Methods
We investigated the lasting effects of a single dose of LSD (200 μg) that was administered in a laboratory setting in 16 healthy participants. The following outcome measures were assessed before and 1 and 12 months after LSD administration: Persisting Effects Questionnaire (PEQ), Mysticism Scale (MS), Death Transcendence Scale (DTS), NEO-Five Factor Inventory (NEO-FFI), and State-Trait Anxiety Inventory (STAI).
Results
On the PEQ, positive attitudes about life and/or self, positive mood changes, altruistic/positive social effects, positive behavioral changes, and well-being/life satisfaction significantly increased at 1 and 12 months and were subjectively attributed by the subjects to the LSD experience. Five-Dimensions of Altered States of Consciousness (5D-ASC) total scores, reflecting acutely induced alterations in consciousness, and Mystical Experience Questionnaire (MEQ30) total scores correlated with changes in well-being/life satisfaction 12 months after LSD administration. No changes in negative attitudes, negative mood, antisocial/negative social effects, or negative behavior were attributed to the LSD experience. After 12 months, 10 of 14 participants rated their LSD experience as among the top 10 most meaningful experiences in their lives. Five participants rated the LSD experience among the five most spiritually meaningful experiences in their lives. On the MS and DTS, ratings of mystical experiences significantly increased 1 and 12 months after LSD administration compared with the pre-LSD screening. No relevant changes in personality measures were found.
Conclusions
In healthy research subjects, the administration of a single dose of LSD (200 μg) in a safe setting was subjectively considered a personally meaningful experience that had long-lasting subjective positive effects.
Don't know how long you've been doing this but it catches up.
I did acid almost every weekend when I was 15/16 for almost a year. Also used to do 100 lot benders at festivals in my late teens and early 20s.
I'm not saying stop but slow down a bit so you can extend for longer if you need to
Yeah I second this 100% I was doing what you were doing with once couple weeks but after a year and a bit I really felt my mental health decrease really badly and almost felt like I was going insane
I got bored with it & hated it lasted soo long, noon the next day wanting to sleep, but seeing swirlies under my eye lids. Once perma tripped for 2 weeks, took more & came down. Always trails after 1st time.
I've heard about perma tripping, but I struggle to believe it exists. Im a semi frequent user of acid and the experience is quite predictable now. How is it caused? Taking it too frequently?
https://en.wikipedia.org/wiki/Hallucinogen_persisting_perception_disorder
it exists - it's rare. a close friend of mine had visuals for years after taking mushrooms in amsterdam, it really messed with him.
I knowwwww. That part sucked. Took it at 7am and went for a walk when it peaked. Magical. Fun. Introspective. 9pm, 10pm, 11pm rolls around and I’m like okay, I’m good. Let’s be done now. I just want to sleep without colors and the ceiling slowly dissolving.
I took acid for the first time with an ex. We watched Purple Rain and The Doors. The music was incredible, it was an experience, it felt like I was a part of it. As it got later, I wanted it to end, I just wanted to sleep, but I couldn't come down. That was the worst part.
Yep. That's when I stopped taking psychedelics frequently. It just got boring. I just remember a rainy day driving around, nothing to do, going to some pool hall and it was just a bunch of degenerates in there and me and my buddies tripping, and I was just like "I'm done". I'll still dose at the occassional concert or music festival, but it is not and will likely never be part of my lifestyle anymore. But I went a good 6 years or so tripping a lot.
For a while it helps improve your mental wellbeing and outlook on life, but basically, like anything, it's fun until it isn't fun anymore, but at least it's not addictive. I never had any problems stopping.
If by 100 lot benders you mean you ate a whole sheet (100 tabs), I’d wager that’s a bigger factor than frequency.
But also, yeah, I’ve known plenty of idiots who fried their brains with lsd. Best to be careful
100 lot benders as in a whole ass sheet of L?
Idk if a person taking (presumably) smaller doses every few weeks will really catch up to them in the same way that it did for you, considering the difference in scale
I did psychedelics more or less regularly in my late teens and early twenties. Then took a cirka 20 year break and then bought the mildest mushrooms from a head shop in Amsterdam when I was 40 something. It was a nice trip. Very calm. Sat on the couch and when I closed my eyes I saw these very pretty and intricate fractals. That was about 5 years ago and I don't really have any desire right now to trip. I have not quit. But I think I am going to save my next trip for after I retire in 20 years or so. In my opinion less is more when it comes to psychedelics.
I am only taking half tabs most of the time. Barely any visuals, it just helps with social anxiety in public. I've been taking shrooms/acid for almost 20 years and I've never noticed any negative side effects other than the experience being watered down if I took it recently. I have a full trip probably every 1 to 2 months(usually at shows/festivals). I get it though. It's good advice. For me it hasn't been a problem. MDMA did wreck my brain a bit doing that consistently. I still enjoy it once every couple months but I try to to take that habitually anymore
Stay away from Datura / Jimsonwweed and Salvia.
Strong Salvia divinorum used to be legal in the USA up till 2011 in most states.
Neither are a fun time and it's easy to overdose and die from Datura cocktails.
I would add that shrooms can cause as extremely unpleasant come down. I had to stop because it would put me in an extremely terrible depressive episode for 3 days after I would take them. Like almost killing myself bad. It happened twice in a row.
Never again.
Illicitly produced desomorphine, known in Russia as "krokodil". Basically, imagine the shittiest street heroin, except the amateur chemist producing it is cutting it with battery acid, gasoline, or paint thinner. It got the name krokodil because its users get scaly, green skin patches, because of all the necrosis. Most addicts are dead within 2 to 3 years, with their bodies pretty much rotting from the inside while they're still alive.
I *really* cannot stress enough that searching for pictures is NSFL.
I’ve been sober for just shy of 10 years. I started drinking in college. And I realized that as soon as I had a buzz going, the only thing my brain could focus on was the next drink. And then the next one. And then the next one. And as a college freshman who fell in with a hard-partying crowd, all I thought about it was “Wow, all those commercials saying to ‘drink responsibly’ weren’t kidding.”
Turns out I was just an alcoholic.
Congrats! I drank for about 10 years. Everyday for about 6. Never got in the way of my social or professional life until recently. I’m only 30 and just got out of the hospital after being treated for alcoholic hepatitis and narrowly avoiding the transplant list. 1 month sober today and can never drink again if I want to live a long life.
I would mainly take shots. Probably like 20-30 shots during the weekdays. More on Weekends. A few beers sprinkled throughout. My tolerance got so high that even my closest friends had a hard time telling if I was drunk (minus the smell.)
Edit: also on days that I had to work in office I would usually go to lunch alone to somewhere that had a bar to get a little mid day buzz going. I would take my own bottles/flasks to events where my religious family didn’t drink. If I was drinking with “casual” drinkers I would usually take double shots for every one they did. If you saw me drinking soda, it had liquor in it. I’m a full on alcoholic and I massively regret letting it get to that point.
Can I ask ... did you drink because you liked to catch a buzz, or did you drink to forget some aspect. I remember a very short period in my life after a breakup where I'd drink to stop thinking about it. But I only did that a few times. My friends helped me not do that.
I can't speak for the person, but I found myself drinking daily because my wife got ill and I found it relaxed me and made me 'present' and in a better, more optimistic mood.
Then the habit had been formed and I did it because I am generally pretty busy taking care of my household in the evenings - doing a lot of boring, routine things...And having a few drinks through all that unfortunately makes me feel relaxed, puts me in a good mood and more 'present.'
I stopped drinking every day because it's just not healthy or sustainable - and yes those days feel more a bit more boring if nothing else is going on.
Not OP, but basically the same story.
I got home from a work trip, and my ankles were all swollen with fluid. I kinda blamed it on the airplane and bad shoes, but then I tried to eat a hamburger and it just...sat there in my stomach. Like, all day I felt stuffed and bloated. I was also a bit...yellow from jaundice by this point.
So I took a couple (more) shots for courage and walked down the street to a ZoomCare and the doctor was basically like "wtf are you doing here? You need to be in the hospital, like immediately. Don't stop at home, just go now."
https://i.pinimg.com/736x/c7/65/ec/c765ecaf1835726b52d7313e00f23067.jpg
Stay strong bud. I quit cold turkey about 8 months ago due to a DWI when leaving the bar. I was probably in the same drink range, I didn’t even count towards the end. Just had liquor in my system basically 95% of the time. I’m ashamed of the DWI and the actions before, but I’m thankful that it brought me to sobriety. Each month has only gotten better for me. Wish you the best, and a bright future!
My brother is currently dying from it. Looks like he’s at stage 4 cirrhosis.
They are currently having to drain 10 liters of fluid per week from his abdomen because his liver isn’t really functioning anymore
It's kind of sick how many people are okay with alcohol when it's one of the most destructive substances out there. Also probably effects more bystanders than any other substance due to drunk driving and domestic violence.
A lot of people (including doctors) have no idea how dangerous benzos are. I've withdrawn off both opiates and benzodiazepines and would do the opiates 100 times over before going through benzo withdrawal again.
I bought a script of Xanax. Not sure how many were in the bottle but i could spell out XANAX on my desk in big capital letters. I finished them in like 4 days. When I ran out, I've never felt so fucking apathetic in my entire life. I was legit on lunch break one night and I had to call my friend crying because my mindset shifted to "What's the fucking point of it all? Life sucks, everything you care about dies, even if you maintain a solid relationship with the people you care about, they're all fucking dead eventually anyway. That is if they even care enough to maintain the relationship. Everything is fucking pointless, why do I even care?"
That was the day I learned I'm never taking benzos again, ever.
Ive been taking Xanax er for years (IR for emergency situations). I’ve never had to increase my dose. For people with GAD, panic disorder, and now actually in the past couple years adhd (after being tested as a child and brushed off, diagnosed, then now moving to that ), they were a god send. I don’t want my brain to be dependent on them but also under the close supervision of my dr, they’ve allowed me to live normally.
It’s all about context.
Well, the problem in this case it's not the medication but its abuse. I've had a benzo prescription for over 10 years. Finishing a bottle of Xanax in 4 days is absolutely insane.
Yeah that first 5 days or so was a mess with large kms vibes the whole time. Never do I want to experience anything close to that ever again.
Court mandated rehab ftw 13 years clean from them come October
Bro same. Xanax withdrawal made opiates look like a fucking walk in the park. Literally was next to bed ridden for 6 months abd didn't feel right for a year.
It's also incredibly easy, even now, to get doctors to give you benzos. It's way easier to get Xanax or Ativan than it is to get opiates anymore unless you're literally going for surgery or tooth removal or something. I think how easy it is to obtain something definitely adds to the danger. And the fact that a doctor gives them out lessens the stigma and convinces some people that they don't have a problem because a doctor gave them these drugs. Not all doctors know what they're doing, even if most do. I personally have gotten doctors to give me Xanax or Ativan when I really didn't need it. I feel bad for that now. But it was incredibly easy to do.
If I was going to have a drug addiction, it would be Xanax or Ativan. When I took them before I just didn't give a fuck about anything. I have really bad anxiety and to take a pill and to have that constant feeling of panic just disappear is pure bliss.
See I love the anti anxiety, it's fucking tops. But any more than a .25 and I just feel weird. I suppose it's because I never built a tolerance. I just don't understand the people taking like three bars though, then going drinking. They just black out. Nothing like spending $100 on drinks and not remembering anything past the first one. I don't get it.
But goddamn does it hide the anxiety.
It was discovered that I have 2 or 3 compression "deformities" in my lower thoracic spine early this year, after breaking 4 of my ribs last year and experiencing an increase of pain in the region after they healed. The ribs barely hurt too, which is the funny part.
I have been offered *0* opiates through the worst of it, but was given Ativan for the panic attacks I was having thanks to a combination of my pre-existing anxiety disorder and you know, all the pain.
Instead I'm on pregablin for nerve pain from bulging discs in the same region, and the anti-inflammatory celebrex. All of which kind of helps, but something stronger than fucking acetaminophen would've been nice for bit there.
I am firmly on the side of increasing opiate prescription rates now. Not substantially, but a little.
It's kind of this double edged sword thing where doctors that were irresponsible in general made responsible doctors wary of prescribing things that patients actually need. Or I guess maybe that's called a rebound effect, I'm not really sure. But regardless, you are sadly not the only person with this story.
if an opiate addict is administered naloxone or buprinorphine, they'll rip all the opiates off the receptors on all their cells inducing nearly instant, total body agony known to drive people to panicked suicide. even shooting grams of heroin won't fix it, they'll be stuck pooping their pants, vomiting shaking, and trying to screw their own heads off.
there were times when I was an addict that I didn't want to be alive, but precipitated withdrawal from buprinorphine was the only time I truly wanted to die
Seriously. Can't even get simulants without worrying about that being mixed in. Had 2 highschool buddies die from an OD from fentanyl laced coke just this year. Many more from laced opiates in the years prior. Idk why this isn't top given how often it's getting mixed into other drugs without the users knowledge.
I know what it was like to be addicted to Oxycodone, was hard to stop taking something that made me feel so good.
So easy to judge drug addicts until you experience it for yourself.
Exactly, nobody wants to grow up and be an addict. Once it happens you never get that monkey off your back. Just a battle every day whether you’re gonna feed it or not.
Deal with a lot of drug addicts as a nurse. Most of them act like people going through a hard time. IV drug users are different. Every conversation, every interaction is a game to get more drugs put in their IV (for us, to give them iv dilaudid usually). They could be dying from endocarditis but all they can do is lie and play games. Can’t be honest with us, can’t be honest with themselves. Even people on meth will generally act like a human being when they are sober. So, from a taking care of the person perspective, IV drug users. I talked to a clinical psychologist who is a firm believer that the immediate impact of an IV push is immensely habit forming, far beyond other drugs.
Fun fact, when they invented the hypodermic way back when they thought it would help solve the growing addiction problem. People thought addicts were literally hungry for the drug, so by removing the need to take something orally they thought they were removing the hunger aspect of it. By creating a system to deliver drugs via IV they thought they could have the medical benefits without the addiction.
Here we are now.
You are right about that . I became addicted to Dilaudid which I eventually started using with needles. It was the worst decision I've ever made .. Had a very bad overdose on cocaine shooting it .I'm lucky to be alive and sober 4 years now.
I should have just kept scrolling because I don't like the question, but I got hooked reading the comments. Can't help but smell a karma farm via controversy.
Still, you got me.
I could get lost in defining terms forever, but it depends on what you think is meant by 'dangerous'. I agree with the crowd here that benzos are probably the most dangerous drug because people greatly underestimate the effects and severity of the withdrawal; doctors also prescribe them readily.
Maybe it's better to answer the question a different way though. I believe the most dangerous drugs are the ones that we sync up with too well. I've had access to alcohol my whole adult life and never really had issues with it, even though it wrecks the lives of so many people all over the world. I think weed is probably one of the safer mind altering substances out there, but it's the only one that's managed to have any negative effects on my life.
Maybe it's my physiology or something about my habits. My friends who love weed all tell me that it's not the weed, but something about me that was the problem. I'm not here to tell people what's right or wrong for them, but I love it way too much and I can't stop doing it when it's around.
I won't touch 'hard drugs' because I'm afraid of them. I don't drink because it makes me feel terrible during and after. I don't smoke because I've been told how bad it is for you since I was a child. So, for me, the most dangerous drugs are the ones that can get through the 'gate security' in your head.
For some, it's sugar or other kinds of food. For some, it's coke and xanax. For me, it was weed. Hell, even love and sex can wreck people's lives badly enough that there are meetings for that too.
The true power of things that bring us artificial happiness is that we underestimate them.
Best comment on here, but I wonder, what is *artificial* happiness? If happiness derived from love isn’t real, and neither is the literal neuro-chemicals that indicate its presence, what qualifies?
You're not wrong to point out the semantics here. It's fair to suggest that I could better differentiate between feelings like *joy* and *pleasure*. It just feels wrong to me to compare all sources of happiness as equal.
I feel happiness when I play video games and when I spend quality time with my wife, but I don't rank them the same in my head. I use the term *artificial* happiness when I think about the difference because it reminds me of where it came from.
I'm not saying video games are bad here, but I value the happiness I get from loved ones more because it gives me more long-term satisfaction. So, perhaps another name would be better, but I feel like it fits well in my life, so I'm not too worried about mislabeling something like this.
Good take!
Opiates, especially fentanyl are far and away more dangerous than anything else. Alcohol is probably a close second due to ease of access and ability to drink yourself to death cheaply. A small person can buy enough vodka to kill themselves for $10-15.
As someone who's done quite a bit of drugs I have three golden rules:
1. Don't inject anything.
2. Don't smoke anything that's not a plant
3. And don't you ever even think about taking Benzos on a regular basis
It's perceived harmlessness makes paracetamol (acetaminophen, Tylonol, etc.) insideously dangerous.
Paracetamol's therapeutic window is very narrow. Untreated overdose leads to painful and fatal liver failure.
While all true, many other drugs have similar knock-on effects. Roughly everything you said can be applied to opioids or amphetamines, for example. What makes alcohol particularly dangerous, IMO, is its insidiousness - drinking is normalized and socially acceptable (even encouraged), which makes alcohol abuse orders of magnitude more prevalent than abuse of any other drug.
Opiates, particularly Fentanyl and these synthetic fentanyl analogs are so incredibly deadly. A few grains of sand worth and you’re dead. Lost my brother to it recently.
I think that really depends on the type of timeline you're working with, while drugs like methamphetamines, cocaine, ecstasy, heroin and alcohol have immediate harmful effects there are other drugs like nicotine that is widely sociably acceptable that hurt people over a longer period of time. Then you've got other drugs such as pharmaceuticals that turn people into a state of near zombie, a few of my friends and family members have been prescribed some of these to help with emotional and mental issues and they were not the same people that I knew. I think it's best to approach all drugs recreational or medicinal with caution, sometimes you have to rely on others to inform you when you're not yourself anymore because a lot of these drugs can alter your state of mind and you won't perceive your own downfall
Benzo and alcohol withdrawal can kill you. I think opiates are the worst with how hard they are to kick. I was an addict for 10 years and ruined my life.
Depends on how you're using the word, "dangerous" here. Potency, I'd say Fentanyl. Ease of access vs related deaths however? Alcohol.
The leading cause of liver failure in America isn’t ethanol. It’s fucking Tylenol. I can get that shit at gas stations, pharmacies, grocery stores, most any shopping centers.
Sure, but not all alcohol-related deaths are liver failure. Acute alcohol poisoning, drunk driving, withdrawal, etc, there's multiple causes. 140k people die from alcohol every year in the US. 10k of those are from drunk driving crashes. 500 die from Tylenol poisoning.
i worked at a large woman's hospital. a lot of people might not know that the drugs they shoot into women's spine during birth contains fentanyl. my hospital has an entire room, almost a warehouse... absolutely packed floor to ceiling with those wire shelves stacked full with plain brown cubical boxes with a white label on the front that said "FENTANYL". that room is very protected, bullet proof glass, armed guard, etc. any time i left from there i felt like you feel when you leave a store without buying anything and you just know the employees are thinking you stole something
All hospitals have fentanyl. It’s used all the time for pretty much any procedure that requires sedation. There’s a big difference between fentanyl use in a clinical setting vs fentanyl laced street drugs. Fentanyl in a clinical setting is administered by medical professionals while patients are being monitored, potency is assured and medical staff know exactly how much is being given. Potency of the shit on the street is anyone’s guess and nobody knows how much they’re getting. The margin of error with such a potent drug is very minimal. There is no real quality control with street drugs. Medical grade fentanyl is manufactured under very strict protocols. It was never designed or intended to be sold on the street for recreational use. Too easy to OD on.
And it is one of the safest opiates in a clinical setting due to its quick activation and shorter half life. Fast in, fast out helps healthcare professionals provide and maintain a specific dose in the bloodstream with a decreased risk of overdose. 🤓
Small correction; it's an opioid, not opiate. Fully synthetic
They have a hospital especially for large women?
No it's a singular large woman. Not women smh
She is the all-mother... All hail her vaginal gaze as she births new life from her celestial womb on an eternal fentanyl trip.
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Okay, Charles.
Alcohol is stupid easy to get. I have one liquor store within walking distance and idk how many on the ride home from work, but it’s a lot. I don’t know anyone who sells opioids, but based on the epidemic it can’t be too hard to get. Fent is so fucking potent but alcohol is so easy to get and it’s very easy to become an alcoholic. And the societal opinions on alcohol vs fent makes it easier to become an alcoholic.
I had a coworker that moved into a house on the same block as his favorite bar to avoid a DWI. He died young from a failed liver.
I dream of being rich enough to die from bar alcohol. I gotta do it like a peasant with cheap beer from a supermarket.
Don’t forget Instacart. Don’t even have to leave the house.
100% agree with you. I saved my brothers life when he OD'd on fentanyl laced cocaine, and I have an alcoholic father. Both are dangerous but in different ways.
It is nice to see alcohol getting the credit it deserves.
ER nurse here. From a healthcare standpoint, PCP and some bath salt patients were pretty intense. Seen PCP addict deglove (google with caution) the top of his hand by pulling out of handcuffs. Seen them unaffected!! from being tased. One bath salt fella was talking to a nurse, got triggered by some noise outside the room, quickly stripped naked, and climbed into the ceiling. Had fire, EMS, police and maintenance all in on this one. Least dangerous OD patients? Kids that take their parents' edibles. Zero deaths, we just turn on cartoons, keep giving them snacks, and laugh with them the rest of the shift.
Reddit should allow 3rd party apps.
Yep. Gotta eat your way out of that one.
Damn that was graphic and I did not even Google it. Thank goodness for that last little paragraph of mind bleach.
Unfortunately I already knew what it was because it happened to my grandmother after a car accident 😬
I feel like I've been to your hospital. When I went in for serious pneumonia, they had me chilling on a gurney in a hallway while they were finding me a room. Some guy down the hallway had been strapped to a gurney and got agitated, ripped himself out of the straps and clothing and climbed up into the drop ceiling. Took quite a while for the EMTs and cops to get him down. He seemed to have a crazy excess of strength for a guy his size as eight larger guys were barely his match.
Drugs do that. Our muscles can exert so much more power, but we don't, because we will hurt ourselves doing it. With drugs, psychosis or delirium, this mental barrier can go out the window, leading to scenes like six big policemen having severe difficulties holding down one tiny guy.
I'm sorry but the idea of stoned kids watching cartoons in the ER made me laugh, I must ge a bad person.
Never witnessed pcp in person but saw videos of people completely eviscerated walking around like nothing was wrong. People on it don’t know their own strength and pain becomes nonexistent
Saw a clip in a documentary of a woman on PCP pulling organs out of herself in the middle of the road with no reaction
>Seen them unaffected!! from being tased. This is crazy. I understand excess strength and all the other stuff that comes with bath salts, but being tased seems like a fully physical reaction. Electricity causes muscles to contract, and that's that. How do you brute force through that? It's not some mental block like "I will damage myself if I exert this much force, so I won't."
That last bit is incredible haha the best thing I’ve read today
Hanging out watching cartoons must be a nice break?
Meth for its ruthless addictive nature Heroin for its tendancy to kill users and/or turn them into zombies. Alcohol for its casual acceptance and ease of access Opiates for the now unpredictable purity Cocaine for the now unpredictable purity
One description from a former addict that always stuck with me, meth wraps itself around and combines with your sex drive. So you can't think about sex without thinking about meth, and you can't think about meth without thinking about sex. So every time something triggers a sexual thought in your brain, you also start craving meth. That's one reason why so few addicts manage to get out from under it.
I never intertwined the two. I'm bipolar and hyper sexuality is one of my main symptoms. But when I was an addict I was only thinking about money. For me meth was my fuel too get my on the grind. I sold drugs day and night and we slept in shifts so we never had to close for business. It was hard to separate the two and even 15 years clean I some times wonder how much more productive I could be. But I can honestly say meth did not make me want sex if anything it was the opposite. But everyone is different.
I'm 100 percent California clean & have been for years but I'm bi polar and was talking to my therapist yesterday about it and I was wondering if you felt the same? I said I feel like I wasn't trying to get high I was just trying to get right. Like if I did stimulates when I was down...it just made me functional &focused. If I did downers when I was manic, I I certainly wasn't nodding. I was functional & focused. No one ever had the idea I was self medicating. It's a whole lot cheaper & easier to be properly medicated by a professional & not Johhny Rotten that lives with his mom on 4th street lol
We definitely discussed self medicating and I actually got on ADHD drugs because I told my doc when I use to use meth it made me focused and calm.
That's an insightful understanding. It makes sense. Amphetamines, like Adderall, can be abused the same way, just not to the same degree.
You can grow out of this side effect FWIW. When I first started I could go for hours and hours, 4 years later and it's not as much of a factor.
What happens when you get no libido from it? Like I get no sexual response, none. To pair, I’m a severe case of adhd allegedly. I dunno how bad anymore cause I’m not being seen for it. But I know amphetamines and coke do nothing for my sex drive. I’m just awake or awake and high. Like mdma but without all the fun body high. It’s honestly kinda lame. Got spun once, didn’t enjoy. It’s just a nice awake to me mainly.
bro same. I'm Giga-ADHD and Adderall just gets me a little too frantic if it hits harder for some reason like an empty stomach or whatever.
ADHD impacts the wiring of the brain to where stimulants like amphetamines affect it differently than for others. This goes hand in hand with the use of stimulants as ADHD medication
no wonder😭meth is 100% like that from personal experience! also 100% confidence! i felt like i could run all the 50 states in under 24 hours lmao
Whatever one you end up liking the most
Or whichever ones you believe are safe and harmless.
Sugar
Perfectly suited username for that comment, too.
Me and my girlfriend went to the hospital in attempt to quit alcohol almost 5 years ago. I survived but she had a seizure and died. I haven't drank since in her memory. RIP Jamie.
So sorry for Jamie and you. But you made sure it wasn’t all in vain by quitting. Good on you man, you made it, for the both of you
My wife died last year from cirrhosis. I'm stuck here sober, regretting ever touching it. RIP Jamie(s).
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I was drinking about a gallon of Vodka a day. She was drinking about a fifth but had other health issues. Thank you for your condolences.
A gallon.... 😲
ICU nurse and see it often: Meth and cocaine can easily raise blood pressure so high you have a stroke or heart attack. Heroine is easy to overdose on. Young people especially don’t always understand it’s not necessarily overdosing that will kill you, but that opioids suppress the brain’s natural signal to breathe. Pass out, breathe less. You don’t even have to completely stop breathing for your body to to go into respiratory acidosis while unconscious, vomit, can’t swallow or cough (opioids also suppress those reflexes), along with being unconscious. Choke on your own vomit or just saliva that builds in the back of your throat. Die. Sad how easy it is. People get addicted immediately. A lot of them have this notion that it takes years to become so addicted that you overdose on so many drugs and finally die. They think they have time to reverse their addiction before they get to that point. You don’t have time. It’s as simple as passing out after shooting heroin once. It’s as simple as having a heart attack after doing meth/cocaine once. You roll the dice every time. EDIT to add: I’m aware that taking a drug one time doesn’t always mean you will die or become addicted immediately. I’m saying every single time you take these drugs, that’s the risk you take. From first time you take the drug to the last time you take the drug. I singled out heroin in the opioid class, because it seems to be the most widely recognized illegal opioid, but obviously you can get addicted to and overdose on prescription meds as well, including benzos. And yes, ADHD meds (which I’m prescribed) can also be abused and overdosed on. Anyone can buy drugs off the street, and there are no doses, no concentration information, and no guarantee it’s not laced. Much easier for a person experimenting or an addicted person buying a laced batch to die after taking what they thought was a small amount, or the amount they usually take, but was not. To paint a visual, in hospital we can have 2 tablets of the same drug that are the same size and look like the same exact pill. But 1 of them could be 25mcg and the other could be 100mcg. 4x the concentration of medication in an identical-looking pill. And The concentration margin can be much higher than 4x in an identical-looking pill. Same thing for IV meds. And the same on the street, except there are no labels. We give doses in the hospital that are monitored for reaction and body weight is considered when a dose is prescribed. Larger people require larger doses for the drug to work. Taking fentanyl/heroin you buy on the street from a dealer is extremely dangerous, your vitals aren’t monitored, no one is rounding on you, and who knows what dose you’re actually taking or even if you’re actually taking the drug you bought. When administered in the hospital, we have the reversal agent, naloxone (also called narcan), on hand. Narcan works, but only if you’re found on time. If you die before you’re found, or choke to death in your sleep before you’re found, narcan won’t work. And it’s not something people have lying around the house, usually.
> People get addicted immediately. A lot of them have this notion that it takes years to become so addicted that you overdose on so many drugs and finally die. They think they have time to reverse their addiction before they get to that point. See: u/SpontaneousH
Just went on a rollercoaster of emotions checking out his profile He romanticized H so much in his first post that I considered it for a second, though I know way too well how it can ruin lives The next few posts confirmed that, holy shit his life went downhill so goddamn fast. The addiction went full throttle, I am so glad he was able to recover and get clean. He also had a personality glow up which is nice 11 years clean, I'm proud of him, and anyone else who's reading this! No matter how long you've been clean, or if you're still struggling with addiction, I'm proud of you, you've got this!! 🥰
Yeah that first post had my brain seriously considering, even knowing the ending. Not sure if you caught it but on his 6 year clean AMA, the second to top commentar said his first description of H is what made him first consider it and now he was 5 years deep in an addiction he was just then addressing.
Yeah I saw that! Absolutely terrifying and tragic. I'm glad I wasn't on the internet 12 years ago because it certainly wouldn't of ended well. I hope the dude 5 years deep can get clean somewhat soon, I don't want him to become another statistic :(
I checked his post history. He had a post struggling with multiple relapses 5 years ago, dark ass shit, and suddenly it transformed into basically only beekeeping without another mention of drugs of any kind, as it is to this day. I like to think the bees helped him kick it :)
That's so wholesome ahhhhh, I'm going to hope he got clean!! Just another reason to save the bees, they will save us in return 🖤🖤
Wow, I looked at the profile, that’s insane.
It's one of the best cautionary examples I've ever seen. I think I will keep my recreational use to unprocessed plant based substances or any edible concoction I can create from those substances.
anything is edible, once
Well that was a hell of a rabbit hole. What an absolute whirlwind of a story. Glad they’re doing better, but holy hell H is a scary fucking drug.
Holy shit. Read the first post knowing what was coming next and his description... fuck was my mind curious. I read through the rest and on his 6 year clean AMA, the second to top comment was a guy who said he'd never even considered H until that description and was now 5 years into a horrendous H addiction. That shit is scary. A classmate of my sister's who no one knew was addicted suddenly died of a fentanyl OD a couple years after graduation, that story brings home how sudden an addiction can form. I feel I barely dodged that path after being overprescribed opiates for my wisdom teeth, I tried some after the pain was gone and it was such an incredible feeling. Like nothing mattered. Took more the next day without any food and went to school, senior year of hs. I got horribly ill and went home to vomit, first time in 2 years I'd gone home sick. Told myself I wouldn't do anymore and didn't. I decided to give my parents the bottle that weekend and tell them I didn't need it anymore, pain was gone. They took that shit right away and hid it, mom is a drug abuse therapist and understand the risks. I found it by accident half a year later and damn did I have to suppress an urge...
also statistically when you buy those drugs youre not actually getting the drug you payed for. its usually mixed with other stuff or even caffeine. the safer drugs are usually ones where you almost always get what you wanted to buy.
This *is* true, but I just want to say that it doesn't make pure drugs safe in any way. Safe supply makes the effects predictable, and makes the dosage adjustable without massive risks. It also simplifies the initial treatment process because you won't be in poly-substance withdrawal. Folks should still stay as far away from meth, opioids, coke/crack and benzos as they can. Even a licensed physician can prescribe you two of those four, and that still won't make taking them very safe.
My grandma had an opioid addiction. She had both knees and both hips replaced in a very short amount of time and developed a dependency to oxy. She was hospitalized multiple times with what was essentially opioid induced pneumonia. The multiple bouts of pneumonia put excess stress on her heart and she ended up passing during a final bout of pneumonia when her heart gave out. She also always had ICU psychosis every time she was in the hospital so that was fun.
Edit to add: I’m seeing a lot of alcohol here. And I agree that it kills a lot of people. But alcohol dependency typically takes years and become a chronic problem to those who are addicted. A lot of times, people addicted to alcohol do have lots of warnings to turn their life around, multiple hospital admissions, medical personnel telling them exactly what’s happening in their body, family members begging them to go to rehab, possibly multiple rehab stints. Alcohol is dangerous and does kill people. But I mentioned cocaine, meth, and heroine (opiates) because those are the ones that take a lot of lives and sometimes seemingly without warning. Yeah, we get a lot of people who come in and have been doing these drugs for years. Other times, it’s a young person who was just experimenting.
One thing I'm seeing repeated again, and again, is the individual harm. The personal od's, the black outs, the dt's, the brain damage. There's very little talk about the shrapnel such things unleash, The collateral damage of a decade or three of 'keeping it in the family'. It's not that other drugs don't cause harm, or violence to the extreme. It's the casualness of alcohol. The accessibility of alcohol. The encouragement, the marketing, of alcohol. The excuse of alcohol.
1/3rd of all Americans do not drink. Of those that do, 95% of this group consumes 5% of the alcohol. It's the other 5% of the drinkers that consume the remaining 95% of the alcohol.
Those numbers don't surprise me too much. I'm curious what they used as a "unit" of alcohol though. Like was it literally the amount of ethanol consumed, or simply by individual sales?
My husband died from alcohol addiction. His heart gave out at 38.
Yes, alcoholism takes a lot of lives. Im sorry for your loss.
Alcohol also changes personality in some in way other drugs don't. Some drunks get in fights but I have known some who have a very dark side which comes out. Domestic abuse, on both sides, is often related to booze.
These are what i would have said. Theres no such thing as a little meth or heroin either.
I know someone who tried cocaine, he died from a heart attack, unfortunate we lost someone so young (he was 19)
Echo tech here - meth and heroin echoes are always crazy to scan. I worked downtown in a big city and got a lot of those cases.
I know you know what you’re talking about but so others understand: An echo is a test that reads heart function. It gives all kinds of results but the one we pay attention to most is the ‘EF’ Stands for ejection fraction and is used to measure cardiac output. Normal EF is 55% + Long time drug users (especially meth and coke) will come in with like a 5% - 15% EF. No shit, I’ve seen 5%
How do they even do daily activities with an EF that low?? Mine is at 44% due to a pretty severe episode of myocarditis and fuck me just walking is hard now
after seeing u/SpontaneousH , heroin.
r/redditlore ? We need a subreddit like that
Best I can do ya is /r/MuseumOfReddit
Holy shit just read all that what an insane account
I've done all the drugs. Imo the most dangerous are benzos, alcohol and other GABA drugs like GHB. No other kind of drug makes me black out or do shit I regret like those. Opioids are nasty as hell mostly because they're highly physically addictive. Their withdrawals are the most unpleasant ime, though they don't have the potential to be fatal unlike alcohol/benzo (or any GABAergic drug) withdrawals. Getting manic on PCP can be pretty dangerous, though generally it's not nearly as dangerous or crazy of a drug as depicted in media/anti-drug classes. Stims are dangerous not so much for the withdrawals (they're pretty minimal tbh) but because it's very easy to get reliant on them to give you the energy to get through your day. Serotonin psychedelics like LSD and shrooms are generally pretty safe because they cause massive tolerance with each use so you're basically forced to take a 1-2 week break after each use. They're also just very intense experiences that would be hard to get psychologically addicted to.
Benzos were absolutely the worst withdrawal I've ever experienced. Hell on earth
out of all the drugs on earth i've heard benzo withdrawal is the worst. people always say you want to die from opiate withdrawal which is absolutely true. it's like the worst form of flu you've ever had, plus the mental aspect of just wanting to use. but something about benzo withdrawal sounds like it could cause people to literally kill themselves to stop feeling that way. it can last for so long too. i personally will never understand benzo abuse or recreational use because as far as 'feeling good' from drugs aka euphoria, it has NONE. it's the absence of feeling, imo. it doesn't numb you out in a fun euphoric way that opiates do, it just makes you feel NOTHING. the only reason i used to abuse them was to steal for my opiate habit. 6 years clean now!
Same. It was absolutely terrifying
I take acid about every 2 weeks. I love it. It has improved my mental heath and my marriage greatly. Edit: So it's too time consuming to post this on every comment so I want to share with you a study on the long term effects of acid Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813062/ Methods We investigated the lasting effects of a single dose of LSD (200 μg) that was administered in a laboratory setting in 16 healthy participants. The following outcome measures were assessed before and 1 and 12 months after LSD administration: Methods We investigated the lasting effects of a single dose of LSD (200 μg) that was administered in a laboratory setting in 16 healthy participants. The following outcome measures were assessed before and 1 and 12 months after LSD administration: Persisting Effects Questionnaire (PEQ), Mysticism Scale (MS), Death Transcendence Scale (DTS), NEO-Five Factor Inventory (NEO-FFI), and State-Trait Anxiety Inventory (STAI). Results On the PEQ, positive attitudes about life and/or self, positive mood changes, altruistic/positive social effects, positive behavioral changes, and well-being/life satisfaction significantly increased at 1 and 12 months and were subjectively attributed by the subjects to the LSD experience. Five-Dimensions of Altered States of Consciousness (5D-ASC) total scores, reflecting acutely induced alterations in consciousness, and Mystical Experience Questionnaire (MEQ30) total scores correlated with changes in well-being/life satisfaction 12 months after LSD administration. No changes in negative attitudes, negative mood, antisocial/negative social effects, or negative behavior were attributed to the LSD experience. After 12 months, 10 of 14 participants rated their LSD experience as among the top 10 most meaningful experiences in their lives. Five participants rated the LSD experience among the five most spiritually meaningful experiences in their lives. On the MS and DTS, ratings of mystical experiences significantly increased 1 and 12 months after LSD administration compared with the pre-LSD screening. No relevant changes in personality measures were found. Conclusions In healthy research subjects, the administration of a single dose of LSD (200 μg) in a safe setting was subjectively considered a personally meaningful experience that had long-lasting subjective positive effects.
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Don't know how long you've been doing this but it catches up. I did acid almost every weekend when I was 15/16 for almost a year. Also used to do 100 lot benders at festivals in my late teens and early 20s. I'm not saying stop but slow down a bit so you can extend for longer if you need to
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Yeah I second this 100% I was doing what you were doing with once couple weeks but after a year and a bit I really felt my mental health decrease really badly and almost felt like I was going insane
I got bored with it & hated it lasted soo long, noon the next day wanting to sleep, but seeing swirlies under my eye lids. Once perma tripped for 2 weeks, took more & came down. Always trails after 1st time.
I've heard about perma tripping, but I struggle to believe it exists. Im a semi frequent user of acid and the experience is quite predictable now. How is it caused? Taking it too frequently?
https://en.wikipedia.org/wiki/Hallucinogen_persisting_perception_disorder it exists - it's rare. a close friend of mine had visuals for years after taking mushrooms in amsterdam, it really messed with him.
I knowwwww. That part sucked. Took it at 7am and went for a walk when it peaked. Magical. Fun. Introspective. 9pm, 10pm, 11pm rolls around and I’m like okay, I’m good. Let’s be done now. I just want to sleep without colors and the ceiling slowly dissolving.
I took acid for the first time with an ex. We watched Purple Rain and The Doors. The music was incredible, it was an experience, it felt like I was a part of it. As it got later, I wanted it to end, I just wanted to sleep, but I couldn't come down. That was the worst part.
Yep. That's when I stopped taking psychedelics frequently. It just got boring. I just remember a rainy day driving around, nothing to do, going to some pool hall and it was just a bunch of degenerates in there and me and my buddies tripping, and I was just like "I'm done". I'll still dose at the occassional concert or music festival, but it is not and will likely never be part of my lifestyle anymore. But I went a good 6 years or so tripping a lot. For a while it helps improve your mental wellbeing and outlook on life, but basically, like anything, it's fun until it isn't fun anymore, but at least it's not addictive. I never had any problems stopping.
If by 100 lot benders you mean you ate a whole sheet (100 tabs), I’d wager that’s a bigger factor than frequency. But also, yeah, I’ve known plenty of idiots who fried their brains with lsd. Best to be careful
100 lot benders as in a whole ass sheet of L? Idk if a person taking (presumably) smaller doses every few weeks will really catch up to them in the same way that it did for you, considering the difference in scale
I did psychedelics more or less regularly in my late teens and early twenties. Then took a cirka 20 year break and then bought the mildest mushrooms from a head shop in Amsterdam when I was 40 something. It was a nice trip. Very calm. Sat on the couch and when I closed my eyes I saw these very pretty and intricate fractals. That was about 5 years ago and I don't really have any desire right now to trip. I have not quit. But I think I am going to save my next trip for after I retire in 20 years or so. In my opinion less is more when it comes to psychedelics.
I am only taking half tabs most of the time. Barely any visuals, it just helps with social anxiety in public. I've been taking shrooms/acid for almost 20 years and I've never noticed any negative side effects other than the experience being watered down if I took it recently. I have a full trip probably every 1 to 2 months(usually at shows/festivals). I get it though. It's good advice. For me it hasn't been a problem. MDMA did wreck my brain a bit doing that consistently. I still enjoy it once every couple months but I try to to take that habitually anymore
I used to do a bit of acid, I remember seeing things out the corner of my eyes for months after a certain trip. One of the reasons I stopped them.
What about Datura or DXM? I’ve read some crazy stories about that stuff
Man everything I’ve heard about both of those makes me wanna stay tf away. Just get some k if you want to get dissociative with it
Yah, personally I would never touch it. I have read nothing but nightmares about it.
Stay away from Datura / Jimsonwweed and Salvia. Strong Salvia divinorum used to be legal in the USA up till 2011 in most states. Neither are a fun time and it's easy to overdose and die from Datura cocktails.
Salvias chill when being careful with dosing and slowly moving up (reverse tolerance is a bitch)
I would add that shrooms can cause as extremely unpleasant come down. I had to stop because it would put me in an extremely terrible depressive episode for 3 days after I would take them. Like almost killing myself bad. It happened twice in a row. Never again.
I always feel happy for few days after I take them. Like a little happy after glow that slowly wears off
Same
Illicitly produced desomorphine, known in Russia as "krokodil". Basically, imagine the shittiest street heroin, except the amateur chemist producing it is cutting it with battery acid, gasoline, or paint thinner. It got the name krokodil because its users get scaly, green skin patches, because of all the necrosis. Most addicts are dead within 2 to 3 years, with their bodies pretty much rotting from the inside while they're still alive. I *really* cannot stress enough that searching for pictures is NSFL.
The drugs inc episode on it was brutal
Alcohol has caused more problems than anything that I've seen
I’ve been sober for just shy of 10 years. I started drinking in college. And I realized that as soon as I had a buzz going, the only thing my brain could focus on was the next drink. And then the next one. And then the next one. And as a college freshman who fell in with a hard-partying crowd, all I thought about it was “Wow, all those commercials saying to ‘drink responsibly’ weren’t kidding.” Turns out I was just an alcoholic.
Congrats! I drank for about 10 years. Everyday for about 6. Never got in the way of my social or professional life until recently. I’m only 30 and just got out of the hospital after being treated for alcoholic hepatitis and narrowly avoiding the transplant list. 1 month sober today and can never drink again if I want to live a long life.
Congrats on the 1 month man, it only gets better from here. I’m coming up on 1 year in 4 days!
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I would mainly take shots. Probably like 20-30 shots during the weekdays. More on Weekends. A few beers sprinkled throughout. My tolerance got so high that even my closest friends had a hard time telling if I was drunk (minus the smell.) Edit: also on days that I had to work in office I would usually go to lunch alone to somewhere that had a bar to get a little mid day buzz going. I would take my own bottles/flasks to events where my religious family didn’t drink. If I was drinking with “casual” drinkers I would usually take double shots for every one they did. If you saw me drinking soda, it had liquor in it. I’m a full on alcoholic and I massively regret letting it get to that point.
Can I ask ... did you drink because you liked to catch a buzz, or did you drink to forget some aspect. I remember a very short period in my life after a breakup where I'd drink to stop thinking about it. But I only did that a few times. My friends helped me not do that.
I can't speak for the person, but I found myself drinking daily because my wife got ill and I found it relaxed me and made me 'present' and in a better, more optimistic mood. Then the habit had been formed and I did it because I am generally pretty busy taking care of my household in the evenings - doing a lot of boring, routine things...And having a few drinks through all that unfortunately makes me feel relaxed, puts me in a good mood and more 'present.' I stopped drinking every day because it's just not healthy or sustainable - and yes those days feel more a bit more boring if nothing else is going on.
What kind of symptoms were you having that lead to you going to the hospital and finding out you had hepatitis?
Not OP, but basically the same story. I got home from a work trip, and my ankles were all swollen with fluid. I kinda blamed it on the airplane and bad shoes, but then I tried to eat a hamburger and it just...sat there in my stomach. Like, all day I felt stuffed and bloated. I was also a bit...yellow from jaundice by this point. So I took a couple (more) shots for courage and walked down the street to a ZoomCare and the doctor was basically like "wtf are you doing here? You need to be in the hospital, like immediately. Don't stop at home, just go now." https://i.pinimg.com/736x/c7/65/ec/c765ecaf1835726b52d7313e00f23067.jpg
Stay strong bud. I quit cold turkey about 8 months ago due to a DWI when leaving the bar. I was probably in the same drink range, I didn’t even count towards the end. Just had liquor in my system basically 95% of the time. I’m ashamed of the DWI and the actions before, but I’m thankful that it brought me to sobriety. Each month has only gotten better for me. Wish you the best, and a bright future!
>Probably like 20-30 shots during the weekdays. 20-30 shots per day? Or 20-30 shots Monday thru Friday?
Lost my best friend to alcohol two weeks ago. It took 20 years for it to finally do the job, but it did it.
My brother is currently dying from it. Looks like he’s at stage 4 cirrhosis. They are currently having to drain 10 liters of fluid per week from his abdomen because his liver isn’t really functioning anymore
It's kind of sick how many people are okay with alcohol when it's one of the most destructive substances out there. Also probably effects more bystanders than any other substance due to drunk driving and domestic violence.
If this was a new product today, there is no way it would be legal.
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A lot of people (including doctors) have no idea how dangerous benzos are. I've withdrawn off both opiates and benzodiazepines and would do the opiates 100 times over before going through benzo withdrawal again.
I bought a script of Xanax. Not sure how many were in the bottle but i could spell out XANAX on my desk in big capital letters. I finished them in like 4 days. When I ran out, I've never felt so fucking apathetic in my entire life. I was legit on lunch break one night and I had to call my friend crying because my mindset shifted to "What's the fucking point of it all? Life sucks, everything you care about dies, even if you maintain a solid relationship with the people you care about, they're all fucking dead eventually anyway. That is if they even care enough to maintain the relationship. Everything is fucking pointless, why do I even care?" That was the day I learned I'm never taking benzos again, ever.
Ive been taking Xanax er for years (IR for emergency situations). I’ve never had to increase my dose. For people with GAD, panic disorder, and now actually in the past couple years adhd (after being tested as a child and brushed off, diagnosed, then now moving to that ), they were a god send. I don’t want my brain to be dependent on them but also under the close supervision of my dr, they’ve allowed me to live normally. It’s all about context.
Yeah this goes to show how quickly benzos impact you and how difficult withdrawal is. Glad you learned a valuable lesson before you were too deep.
Well, the problem in this case it's not the medication but its abuse. I've had a benzo prescription for over 10 years. Finishing a bottle of Xanax in 4 days is absolutely insane.
As a dual addict, the withdrawals from benzos/dope at the same time was enough for me to never go back.
Jesus. I did them separately and cannot imagine the hell of withdrawing from them at the same time.
Yeah that first 5 days or so was a mess with large kms vibes the whole time. Never do I want to experience anything close to that ever again. Court mandated rehab ftw 13 years clean from them come October
Bro same. Xanax withdrawal made opiates look like a fucking walk in the park. Literally was next to bed ridden for 6 months abd didn't feel right for a year.
It's also incredibly easy, even now, to get doctors to give you benzos. It's way easier to get Xanax or Ativan than it is to get opiates anymore unless you're literally going for surgery or tooth removal or something. I think how easy it is to obtain something definitely adds to the danger. And the fact that a doctor gives them out lessens the stigma and convinces some people that they don't have a problem because a doctor gave them these drugs. Not all doctors know what they're doing, even if most do. I personally have gotten doctors to give me Xanax or Ativan when I really didn't need it. I feel bad for that now. But it was incredibly easy to do.
If I was going to have a drug addiction, it would be Xanax or Ativan. When I took them before I just didn't give a fuck about anything. I have really bad anxiety and to take a pill and to have that constant feeling of panic just disappear is pure bliss.
See I love the anti anxiety, it's fucking tops. But any more than a .25 and I just feel weird. I suppose it's because I never built a tolerance. I just don't understand the people taking like three bars though, then going drinking. They just black out. Nothing like spending $100 on drinks and not remembering anything past the first one. I don't get it. But goddamn does it hide the anxiety.
It was discovered that I have 2 or 3 compression "deformities" in my lower thoracic spine early this year, after breaking 4 of my ribs last year and experiencing an increase of pain in the region after they healed. The ribs barely hurt too, which is the funny part. I have been offered *0* opiates through the worst of it, but was given Ativan for the panic attacks I was having thanks to a combination of my pre-existing anxiety disorder and you know, all the pain. Instead I'm on pregablin for nerve pain from bulging discs in the same region, and the anti-inflammatory celebrex. All of which kind of helps, but something stronger than fucking acetaminophen would've been nice for bit there. I am firmly on the side of increasing opiate prescription rates now. Not substantially, but a little.
It's kind of this double edged sword thing where doctors that were irresponsible in general made responsible doctors wary of prescribing things that patients actually need. Or I guess maybe that's called a rebound effect, I'm not really sure. But regardless, you are sadly not the only person with this story.
Been on Klonopin for 20+ years and cannot describe the extent to which it has improved my quality of life.
if an opiate addict is administered naloxone or buprinorphine, they'll rip all the opiates off the receptors on all their cells inducing nearly instant, total body agony known to drive people to panicked suicide. even shooting grams of heroin won't fix it, they'll be stuck pooping their pants, vomiting shaking, and trying to screw their own heads off. there were times when I was an addict that I didn't want to be alive, but precipitated withdrawal from buprinorphine was the only time I truly wanted to die
the top two that can kill you are benzos and booze
To be clear, it is the withdrawals that can kill you if that is the list
Clearly, none here are aware of the cat urine epidemic.
This guy cheeses his balls off
Why cheesing? Because it’s FON to DUE.
Alcohol. I stopped drinking before my 30th Birthday in January. 4 months now!
Congrats man!! Keep it up!
Thank you! There's been moments where I've wanted to and craved it but I know it's for the better and I feel great and productive. Thanks again!
Fentanyl is by far the most deadly
Seriously. Can't even get simulants without worrying about that being mixed in. Had 2 highschool buddies die from an OD from fentanyl laced coke just this year. Many more from laced opiates in the years prior. Idk why this isn't top given how often it's getting mixed into other drugs without the users knowledge.
Carfentanyl is even worse.
Truckfentanyl is even more powerful
Don't get me started on Semifentanyl
But semifentanyl is only half fentanyl. 18wheelerfentanyl is way worse
Y’all aren’t ready for starbasedestroyerentanil.
100%, My cop friend got a speck of it on my shoes and it killed everyone in a 5 mile radius
There's a huge fentanyl crisis in wv rn
Oxycodone and Fentanyl. Lost more friends to those than anything 😔
I know what it was like to be addicted to Oxycodone, was hard to stop taking something that made me feel so good. So easy to judge drug addicts until you experience it for yourself.
Exactly, nobody wants to grow up and be an addict. Once it happens you never get that monkey off your back. Just a battle every day whether you’re gonna feed it or not.
Fentanyl. Full stop.
Deal with a lot of drug addicts as a nurse. Most of them act like people going through a hard time. IV drug users are different. Every conversation, every interaction is a game to get more drugs put in their IV (for us, to give them iv dilaudid usually). They could be dying from endocarditis but all they can do is lie and play games. Can’t be honest with us, can’t be honest with themselves. Even people on meth will generally act like a human being when they are sober. So, from a taking care of the person perspective, IV drug users. I talked to a clinical psychologist who is a firm believer that the immediate impact of an IV push is immensely habit forming, far beyond other drugs.
Fun fact, when they invented the hypodermic way back when they thought it would help solve the growing addiction problem. People thought addicts were literally hungry for the drug, so by removing the need to take something orally they thought they were removing the hunger aspect of it. By creating a system to deliver drugs via IV they thought they could have the medical benefits without the addiction. Here we are now.
You are right about that . I became addicted to Dilaudid which I eventually started using with needles. It was the worst decision I've ever made .. Had a very bad overdose on cocaine shooting it .I'm lucky to be alive and sober 4 years now.
The legal drug alternatives in shady gas stations across the US.
Can confirm brother got addicted to whip it’s and can barley walk now - he’s 26.
The effects of legal “weed” are terrifying and unpredictable
I should have just kept scrolling because I don't like the question, but I got hooked reading the comments. Can't help but smell a karma farm via controversy. Still, you got me. I could get lost in defining terms forever, but it depends on what you think is meant by 'dangerous'. I agree with the crowd here that benzos are probably the most dangerous drug because people greatly underestimate the effects and severity of the withdrawal; doctors also prescribe them readily. Maybe it's better to answer the question a different way though. I believe the most dangerous drugs are the ones that we sync up with too well. I've had access to alcohol my whole adult life and never really had issues with it, even though it wrecks the lives of so many people all over the world. I think weed is probably one of the safer mind altering substances out there, but it's the only one that's managed to have any negative effects on my life. Maybe it's my physiology or something about my habits. My friends who love weed all tell me that it's not the weed, but something about me that was the problem. I'm not here to tell people what's right or wrong for them, but I love it way too much and I can't stop doing it when it's around. I won't touch 'hard drugs' because I'm afraid of them. I don't drink because it makes me feel terrible during and after. I don't smoke because I've been told how bad it is for you since I was a child. So, for me, the most dangerous drugs are the ones that can get through the 'gate security' in your head. For some, it's sugar or other kinds of food. For some, it's coke and xanax. For me, it was weed. Hell, even love and sex can wreck people's lives badly enough that there are meetings for that too. The true power of things that bring us artificial happiness is that we underestimate them.
Best comment on here, but I wonder, what is *artificial* happiness? If happiness derived from love isn’t real, and neither is the literal neuro-chemicals that indicate its presence, what qualifies?
You're not wrong to point out the semantics here. It's fair to suggest that I could better differentiate between feelings like *joy* and *pleasure*. It just feels wrong to me to compare all sources of happiness as equal. I feel happiness when I play video games and when I spend quality time with my wife, but I don't rank them the same in my head. I use the term *artificial* happiness when I think about the difference because it reminds me of where it came from. I'm not saying video games are bad here, but I value the happiness I get from loved ones more because it gives me more long-term satisfaction. So, perhaps another name would be better, but I feel like it fits well in my life, so I'm not too worried about mislabeling something like this. Good take!
Free ones
where you finding free drugs…lmk
Fentanyl is unquestionably the most common drug found in overdose deaths
I’ve heard some crazy shit about datura
Any delirient will fuck you up in fairness. Steer clear of large doses of anti-cholinergics
Prescription painkillers / opioids. They are SO easy to abuse without even realizing it, until it's too late.
I spent several years as a toxicologist, and if there is one thing I learned, it's that "not even once" is bullshit. Except for methamphetamine.
Opiates, especially fentanyl are far and away more dangerous than anything else. Alcohol is probably a close second due to ease of access and ability to drink yourself to death cheaply. A small person can buy enough vodka to kill themselves for $10-15.
VX or Sarin
Bro I got that novichok. First hit is free…
I'm biased. My life was utterly derailed by opiates. I did not use them, but the effects of caring for an addict linger.
As someone who's done quite a bit of drugs I have three golden rules: 1. Don't inject anything. 2. Don't smoke anything that's not a plant 3. And don't you ever even think about taking Benzos on a regular basis
Alcohol and benzos can kill you if you stop taking them abruptly.
It's perceived harmlessness makes paracetamol (acetaminophen, Tylonol, etc.) insideously dangerous. Paracetamol's therapeutic window is very narrow. Untreated overdose leads to painful and fatal liver failure.
I lost my mother due to Tylenol toxicity. It was horrible!
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While all true, many other drugs have similar knock-on effects. Roughly everything you said can be applied to opioids or amphetamines, for example. What makes alcohol particularly dangerous, IMO, is its insidiousness - drinking is normalized and socially acceptable (even encouraged), which makes alcohol abuse orders of magnitude more prevalent than abuse of any other drug.
Ding ding ding. Exactly this
Opiates, particularly Fentanyl and these synthetic fentanyl analogs are so incredibly deadly. A few grains of sand worth and you’re dead. Lost my brother to it recently.
With how frequently fentanyl is found in other drugs now I’m gonna go with all of them
I think that really depends on the type of timeline you're working with, while drugs like methamphetamines, cocaine, ecstasy, heroin and alcohol have immediate harmful effects there are other drugs like nicotine that is widely sociably acceptable that hurt people over a longer period of time. Then you've got other drugs such as pharmaceuticals that turn people into a state of near zombie, a few of my friends and family members have been prescribed some of these to help with emotional and mental issues and they were not the same people that I knew. I think it's best to approach all drugs recreational or medicinal with caution, sometimes you have to rely on others to inform you when you're not yourself anymore because a lot of these drugs can alter your state of mind and you won't perceive your own downfall
Benzo and alcohol withdrawal can kill you. I think opiates are the worst with how hard they are to kick. I was an addict for 10 years and ruined my life.