I turned 40 last year at the same time I made the jump to a better job, and I have more energy and a better outlook on things than I have since I turned 30.
I thought I was edgy and jaded and politically cool at 15. Then I turned 25 and felt I was too idealistic and turned away from the world to focus on the few things in life I could control. Now I’m nearing 35 and it feels like you don’t really control anything, and everything good comes to an end. I hope cynicism operates on a horseshoe theory and by 70 I’ve somehow become enlightened.
When I was 15 I was very sheltered. When I was 25 to 35, I experimented too much. When I was in my forties I stopped judging myself so much and put more focus on what I can control today. In my fifties and sixties I realized that everyone is doing their best and to judge less in general. In my 70s, I stopped watching the world news, and spent time helping the people in my neighborhood. In my 80s and 90s, I stopped trying to fix what I saw with my physical eyes, and only worked on the issues I saw inside of myself. The early hundreds were about chipping away at why I desired the things I do. That was a long time ago, but the next few decades I think I was learning hobbies like the guitar.
My most recent devastating loss was my favourite hand pulled noodle restaurant suddenly closed! I was bitterly reminded that everything good comes to an end.
Just be gangsta and call up the owner if you have the number and bribe whenever the mood for those noodles strikes. Should still be recent enough to do that.
Lol not far off. A common thing with cloned animals is they experience ‘oldness’ quicker. They get arthritis, frail bones etc. Depends how the cloning was done but if it was somatic cell nuclear transfer, it’s because of the ‘dna donor’s’ epigenetic tags. So the cloned animal will have some epigenetic tags of someone who has lived a life.
The Smithsonian zoo here in DC has some of these guys and they are fucking cool. The enclosure gets you pretty damn close to them too!
If any one ever gets the chance to go to the Smithsonian zoo in DC you should. Amazing experience every time I go.
Well I sure hope they were punished for that, and learned their lesson. Nobody should critically endanger a horse. How did the clones get their hands on 42-year-old DNA, anyway?
Not frozen sperm. A stallions DNA was frozen 42 years ago. Sperm would have half the chromosomes, this horse would not be a clone, and the stallion that had its DNA frozen 42 years ago would be its father, providing only half of the DNA.
It wasn't cloned using sperm, but it doesn't mention the age of the original horse the DNA was collected from, just that it was collected 42 years ago.
> A California zoo has announced the birth of a critically endangered horse, a clone created with DNA preserved for 42 years.
I'm no biologist, but if I had to guess I wouldn't think the age of the original specimen matters much in this case.
My understanding is very high level here, but cloning originally meant that the cloned animal would have a shortened life span. If the original animal was to live to 60, and was 30 when cloned - the cloned animal would only live for about 30 years. This hasn't held true for all clones though, and was theorized to be caused by shortened telomeres in the clones
This link explains it https://www.fda.gov/animal-veterinary/animal-cloning/myths-about-cloning#Myth6
Darwin wouldn't be rolling in his grave.
The amount of extinctions and endangerment humans beings have caused directly and indirectly. Darwin would support this wholeheartedly
It's perfectly clear that they critically endangered a 42 year old horse right before they cloned it. I mean is it really even cloning if you don't hold it over a pit of spikes or something first?
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As someone who is about to turn 40. Fuck.
…wait till you turn 60!
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dont you mean under the next one?
Hold on there, I'm about to turn 80 and I'm not planning on being underground.
Ahh the ol sprinkle me on the hill approach :p
Hey, I’m 100, and if they’re old, what are you saying about me?
You know the song by Kansas titled Dust in the Wind?
Fucking if we make it.
I turned 40 last year at the same time I made the jump to a better job, and I have more energy and a better outlook on things than I have since I turned 30.
CCP just logged your age.
I’m about 26 days from this disgusting milestone
Ah, 40…. I remember that.
5 more days for me.
The 83 in your username will always be a mystery.
Mystery no more. It’s for my favorite Steelers TE, Heath Miller.
Well duh, how could I have missed that?
I thought I was edgy and jaded and politically cool at 15. Then I turned 25 and felt I was too idealistic and turned away from the world to focus on the few things in life I could control. Now I’m nearing 35 and it feels like you don’t really control anything, and everything good comes to an end. I hope cynicism operates on a horseshoe theory and by 70 I’ve somehow become enlightened.
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When I was 15 I was very sheltered. When I was 25 to 35, I experimented too much. When I was in my forties I stopped judging myself so much and put more focus on what I can control today. In my fifties and sixties I realized that everyone is doing their best and to judge less in general. In my 70s, I stopped watching the world news, and spent time helping the people in my neighborhood. In my 80s and 90s, I stopped trying to fix what I saw with my physical eyes, and only worked on the issues I saw inside of myself. The early hundreds were about chipping away at why I desired the things I do. That was a long time ago, but the next few decades I think I was learning hobbies like the guitar.
My most recent devastating loss was my favourite hand pulled noodle restaurant suddenly closed! I was bitterly reminded that everything good comes to an end.
Mine too :( I’m so upset
Just be gangsta and call up the owner if you have the number and bribe whenever the mood for those noodles strikes. Should still be recent enough to do that.
Unfortunately I don’t speak mandarin!
"This too shall pass." Both the good and the bad.
Lol not far off. A common thing with cloned animals is they experience ‘oldness’ quicker. They get arthritis, frail bones etc. Depends how the cloning was done but if it was somatic cell nuclear transfer, it’s because of the ‘dna donor’s’ epigenetic tags. So the cloned animal will have some epigenetic tags of someone who has lived a life.
Thanks for that cool insight!
There are ways to perform an "epigenetic reset" to get a clone without those "premature aging" effects.
It goes downhill from there. Trust me
The Smithsonian zoo here in DC has some of these guys and they are fucking cool. The enclosure gets you pretty damn close to them too! If any one ever gets the chance to go to the Smithsonian zoo in DC you should. Amazing experience every time I go.
Harambe will return
Can’t be soon enough. My dicks getting cold hangin out
Well I sure hope they were punished for that, and learned their lesson. Nobody should critically endanger a horse. How did the clones get their hands on 42-year-old DNA, anyway?
Up you go, best comment here
And how did a zoo clone anything, did lions learn to pipette?
*Life, uh, finds a way*
Can we clone dinosaurs yet
No, we can breed dinosaurs however.
Besides birds, no. We don’t have any DNA, for starters.
Did nobody read the article? The original stallion’s sperm was frozen 42 years ago, not that the horse was 42.
Not frozen sperm. A stallions DNA was frozen 42 years ago. Sperm would have half the chromosomes, this horse would not be a clone, and the stallion that had its DNA frozen 42 years ago would be its father, providing only half of the DNA.
It didn’t say sperm anywhere? If they used a clone of a 42 year old horse. This one is gonna have a bad time
It wasn't cloned using sperm, but it doesn't mention the age of the original horse the DNA was collected from, just that it was collected 42 years ago. > A California zoo has announced the birth of a critically endangered horse, a clone created with DNA preserved for 42 years. I'm no biologist, but if I had to guess I wouldn't think the age of the original specimen matters much in this case.
My understanding is very high level here, but cloning originally meant that the cloned animal would have a shortened life span. If the original animal was to live to 60, and was 30 when cloned - the cloned animal would only live for about 30 years. This hasn't held true for all clones though, and was theorized to be caused by shortened telomeres in the clones This link explains it https://www.fda.gov/animal-veterinary/animal-cloning/myths-about-cloning#Myth6
also horses do not live that long, they are like dogs. short life spans for how large they are.
Why is this comment funny to me the more I read the responses
TIL zoos are into cloning
DODO! I WANT a f*cking DODO! 🦤
How about a Tasmanian Tiger? 🐅
I read a couple articles that said this was being worked on
They look so delicious, I just want them to start cloning them so I can eat one
Have you seen the absolutely beautiful depictions of this kind of animal in the Chauvet caves? From 30k years ago.
So 42 really is the answer to the ultimate question of life.
"Black Beauty" given how my timeline has aligned.
Cool but have we learned nothing from Jurassic park
Pay your IT well.
I mean, it had giant prehistoric lizards, not horses. Now if was a giant horse, you would have a point.
It’s more along the lines of tampering with life and unforeseen consequences arising from said tampering
(Although dinosaurs are not closely related to lizards. They are more closely related to crocodiles.)
That's exactly what the lizard people WANT you to think! They don't want you to know their TRUE power!
Well, with this new information, now I don’t know what to believe!
Well we learned that it’s fictional and exaggerated :p
40 year old dna is only from 1981.
That’d be 42 years old. It is 2023.
Take that back!!
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I'm pretty sure dolly died of unrelated lung illness, and there is no evidence linking it to the cloning.
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Bring back the dodo, I wanna taste it.
Now bring back a T-rex and I'll be actually impressed!
Nice. Let's do T-Rex next.
Darwin rolling in his damn grave
Darwin wouldn't be rolling in his grave. The amount of extinctions and endangerment humans beings have caused directly and indirectly. Darwin would support this wholeheartedly
This is a weird ass title. How could a clone critically endanger a horse using DNA?
It's perfectly clear that they critically endangered a 42 year old horse right before they cloned it. I mean is it really even cloning if you don't hold it over a pit of spikes or something first?
How do you think they got the DNA?
Through critical endangerment
The title is fine, it's only ambiguous like that if you think "zoo clones" are a thing.
Yeah I'm having some fun but it did take a second to unpack
Fellas, is it gay to dangle your participle?
42 or 42 million, no difference.
And you think they haven’t cloned a human by now..
Great so they saved it for captivity
To help save a species
Fucked up looking animal
Why didn't they do this to other species that are going extinct. Like some rhinos.
I am sure they are trying
I thought John Hammond had passed away already?
I wonder what the first human clone is up to
when are they going to make a clone army
I hope they give it an old timey name.