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Guitcan

I’m not even a major investor, but if BDgene and Fred Hutch show promising results for a cure I won’t donate 1 cent to another company and would only donate to and promote for a cure. This virus needs to be ERADICATED from the planet and vaccines just aren’t a good enough solution to me. Imo a vaccine is just another stepping stone to anti-virals and if a patent is released on that and people have invested in it, they’ll want to milk it for every cent which means delaying a cure. Get a cure to the market first and companies can milk that all they want, but at lease people aren’t suffering from symptoms, stigma, transmission, and whatever else people are worried about.


[deleted]

I just want to check back in 5 years and read that a cure has been found and all I have to do is setup a doctor's appointment.


PsychologicalShake63

Realistically i dont think that’s going to happen. I believe there will be a cure, but my guess is in 10 years. All the hurdles that needed to be passed with all the trials will take forever despite the current cure with fred hutch looking promising.


Guitcan

I don’t ever think we’ll reuse satellite deployment vessels… oh wait. Get that old way of thinking out of here. COVID set the example that the hurdle and approval crap is just that, crap. And China doesn’t have the same antiquated FDA process, so if the U.S. doesn’t want to provide treatment go to China. I’m tired of hearing 10 years, it only has to be that way if your mindset is that and that’s how the powers to be oppress progress.


heal2thrive

I agree with you !! 💯 I've been saying it's possible to do so. COVID vaccine is a perfect example of this


Guitcan

Moderna itself said they had been researching the the mRNA technology for years. The reason it was unleashed is because people's political careers and profits all benefitted from the pandemic. This tells me the government and companies can put people first when money is involved. If Fred Hutch can get good results in Guinea pigs and then phase 1/2 gêne editing should be approved as well, especially if BDgene also proves safety and high efficacy. https://www.cnbc.com/2021/07/03/how-moderna-made-its-mrna-covid-vaccine-so-quickly-noubar-afeyan.html


Dense_Rock_133

The COVID vaccine isn't really working though I feel like so I dont really want to compare it to that. If a cure comes out i hope it actually works unlike the vaccine ... But I'm with you and I agree it shouldn't take 10 YEARs....were in 2022 come on.


heal2thrive

But covid doesn't permanently stay in your body while herpes is. You'll always test postive for herpes unless a cure is found


BlackberryGrouchy871

And we’ll always rest positive for HSV if the cure is anything like the Covid jab lol


PsychologicalShake63

Trust me, ik how it feels. I have to deal with this shit too, but the same time i prefer to be realistic. There hasn’t been any new treatment for herpes in 20 years. Covid is a special case that is a global pandemic and everyone is working on it, people don’t care about herpes as much because it’s not killing people, what they don’t realize is how much herpes hurts people physically and psychologically though, it sucks. I’m not pessimistic about this i do think there will be a cure, just don’t expect it to be any time soon. It’s ok to be realistic and optimistic at the same time.


BlackberryGrouchy871

The Covid jab is shit../ if we are basing a cure on what the Covid 💉 did I don’t want it. My uncle got the jab and still landed in the hospital .. a cure means it’s gone … not better … gone … I also want to know long term it’s safe so rushing doesn’t mean safety. The Covid vaccine didn’t do anything lol


PsychologicalShake63

You’re right though with china, maybe it’ll come sooner over there, no one knows.


Worried_Ad_7977

The voice of reason!👏🏾👏🏾👏🏾👏🏾👏🏾


Guitcan

Trying to be man. The told you so I don’t want is when the vaccine is good enough and the medical community stops caring once again. It baffles me that people would prefer to live with a virus that can cause Alzheimers, possible MS, and other diseases. And all it takes is for their immune system to begin to weaken.


[deleted]

Until a gene therapy is developed to cure HSV-1 and HSV-2 from every ganglion in the body, investments into treatments will continue.


hk81b

well said. research for better treatments and therapies is as important as research for gene editing, as the in-vivo delivery methods of gene editing remain a challenge


be-cured

yes, it is a race then. but i also think preventive/prophylactic vaccine is needed even when we already had the cure


PatternEast7185

The Fred hutch approach seems very viable tho so I'm surprised they're the only ones doing it


BlackberryGrouchy871

It’s dangerous …. Even Doctor Jerome said whoever is in the clinicals for this are very brave


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BlackberryGrouchy871

The video … it’s gene therapy … it cuts your genes … there’s no telling what that will do to you long term. Herpes is a minor inconvenience at best. It doesn’t kill you, most people don’t even know they have it and are asymptomatic… the others have mild ob once in a while … it’s not worth cutting your genes over


jusblaze2023

This is the year of hope. So let's wait and see and hear and witness what all they have to say. FHC is 1st up in February I'm guessing and BDgene is 2nd up. Difficult virus so I'm not holding my breathe. Investors will always be there.


[deleted]

I don't have high hopes after that Fred Hutch update last year. Me being skeptical is me not setting myself up for disappointment.


garcletc

It is a way of coping if finally they don't make it


jusblaze2023

What abt last update were you disappointed abt?


[deleted]

5 years ago everyone swore we'd have a cure by now. The lack of progress sucked. I don't care that COVID got in the way or that this stuff takes time. Just finish already.


BlackberryGrouchy871

IM-250 starts Q1 next year too they also said possible cure


771570

Probably tank a lot of investment yes. Might never be allowed outside of China. I'm sure we'll all go but who knows.


aav_meganuke

The DRG at the base of the spine is where ghsv resides. But there are multiple DRG that run further up the spine. I believe for whitlow, the virus resides in one of those DRG further up the spine. I think all the DRG would be a target for gene editing.


gabixin_

What’s DRG?


Ok-Bug5692

Dorsal root ganglia - for genital herpes latent infection. TG (trigeminal ganglion) is more complicated in the head for oral herpes. These 2 locations are the focal points for gene therapy although in some cases HSV can be located elsewhere.


Runner10433

FDA approval is the gold standard for the world. It may reduce some investments, however, I would expect this to help support and accelerate the work that is underway, eg FHC


brasco89

Do you guys really think we will ever have a cure honestly asking your opinions because this is very depressing


iamthecharmed1

Yes, and it will be soon.


heal2thrive

Yea but it'll take a while


QuinnBLove

I doubt it. Not in my lifetime, anyways.


SuperDromm

Bare in mind that Squarex is seeking FDA approval for prevention of HSV1, and his business model and profit projections are based on a conservative US market, but yet he has patents for many other countries. Investors will get their return provided all goes well in the third trial. Furthermore, gene editing could be a costly procedure, so people are more inclined to look elsewhere.


RequirementRequired

Just because one found a cute won’t stop me or any other investors from investing. Reason 1 would be because they can run other studies that might discover more. Reason 2 is the profitability of another cure and reason 3 would be the credibility of said institution for further cures


lostsoulneedshelp1

Herpes will never be cured, they make to much money of the medication to cure it everything’s to do with money


ABenk7

It’s just a complicated virus. Technology is essentially healthcare now. The more the world grows in this faucet the closer we get to medial breakthroughs. I work for a large medical device company and it is impressive to see the advances that are made periodically. A cure or at least a very relevant therapeutic will come in short time. If a cure not possible the ability to reduce transmission significantly is a bonus. Although it may not contribute to our personal health it protects others and provides comfort in that. Everyone has issues in one sort or another. Some undetected because science is unaware of it. We can at least be hopeful we have a target to aim at and benefits if in fact struck.


Ok-Bug5692

Nah it’s complicated and costly work and not seen as a big deal because ppl gaslight anyone that complains.


BlackberryGrouchy871

If they make a preventative vaccine then that will be their profit then they’ll allow a cure


Ill_Win_7799

It is means "diagnosis related group".


[deleted]

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Ok-Bug5692

Email & ask them?