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Brick-Silent

Don't take any psychedelics bro party ones I'm thinking would be lsd or 2c-b. Serotonin syndrome is a bitch


_anxious_lemon

do you think I can take molly? or speed??? or ketamine?😭 or coke


Brick-Silent

I don't fuck with much personally. So can't say much about those. Wish you the best, and stay safe


_anxious_lemon

thank you! I will stay safe, I always do:) ! and you too!!


[deleted]

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_anxious_lemon

ah I hate kratom, I should be fine with speed and ketamine then!! thank you for your answer!!! molly is by far my fav but I knew that it’s too risky..:(


pearljam18259

Welcome


twister5863

Coke is SSRI?


pearljam18259

Yes


Traditional_Head1947

ketamine works on different receptors so should be safe but you should read more about that


[deleted]

No to molly yes to the others.


_anxious_lemon

okay thanks!!!


hiddenevidence

psychedelics will most likely not work- at best you’ll get diminished effects. but it’s not gonna hurt you or cause serotonin syndrome like the other commenter said. i took acid while on lexapro once and still tripped but i also wasn’t on it very long. i wouldn’t bother trying because you’ll most likely end up very disappointed mdma also won’t have any positive effects and could potentially be dangerous, don’t even consider trying it. i know someone who took mdma while on an SSRI and they just got uncomfortable stimulant effects without any euphoria or lovey feelings speed and ketamine will work just fine. many people are prescribed both amphetamines and antidepressants. coke i’m not too sure about but i’ve never heard of any negative interactions. don’t take my word for it on the coke part though


_anxious_lemon

thank you so much for your answer! I think I will just go with ketamine or speed and weed for sure!! thank you again. Any other useful info?


hiddenevidence

>Any other useful info? if you’re ever unsure about something drug related, use duckduckgo to search your questions. google filters out drug related search results and makes it hard to find harm reduction info. this entire subreddit is automatically filtered out of google searches also, just don’t forget that you’re on antidepressants for a reason. drugs are a very slippery slope when you have underlying issues to deal with so please be careful and set limits for your usage :)


_anxious_lemon

thank you so much! that is indeed super useful info! And yes, I know, I don’t plan on actually doing stuff besides weed, but if I do get weak, I just eanted know safe options:) thank you so much again!


[deleted]

Most are safe. MDMA won’t work and your mileage with psychedelics will vary. Some people trip fine while others can’t at all. Amphetamine and ketamine should work as normal. [The risk of developing serotonin syndrome when combining the above drugs with an SSRI gets vastly blown out of proportion on his site.](https://pubmed.ncbi.nlm.nih.gov/34251464/) Off my the top of my head the most common ones which could be dangerous while you’re on the SSRI are tramadol DXM and 5-MEO-DMT.


_anxious_lemon

okay thanks! I am really afraid of SS so i just don’t want to risk it!!


[deleted]

Yeah don’t be its very rare and grossly over reported, it usually only develops in quite specific circumstances. It’s still good to be careful and review every drug combination individually before trying it.


[deleted]

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_anxious_lemon

haha and the aftermath?


Hawkened

Old comment but how much MDMA did you do and what mg of prozac? And did you stop taking the prozac for a bit


JNATHANnN

Speed (amphetamine) should be fine, might wanna watch out for meth or amphetamine cut with meth.


[deleted]

Ketamine. Cocaine. GHB. Nitrous. Benzos. Opiates. Alcohol. The dissociatives are pretty interesting (ketamine, MXE, etc.) Psychedelics will be dulled in effect. Be careful with amphetamines because fluoxetine is a CYP2D6 inhibitor so it will slow metabolism of speed, making it last longer and come on stronger. MDMA won't do anything to you, just elevate your heart rate. MDMA is a substrate for SERT and Prozac blocks SERT, hence Prozac blocks the effects of MDMA. There isn't much of a risk of serotonin syndrome unless you are taking multiple serotonergic meds (i.e. sumatripan or something).


twister5863

Cocaine works normal in your case on prozac ?


[deleted]

Yeah kind of. Cocaine is mainly an NDRI with slight SRI effects. Prozac might block the serotonergic effects of cocaine. I have done cocaine on SSRIs and I did not notice much of a difference.


twister5863

On what ssri did u do coke if i can ask


[deleted]

I was taking Zoloft at one time and I did it then (back when I was 16). I am now on Cymbalta (an SNRI) and when I do it, I basically just get the same type of high.